2021 American Transplant Congress
CEACAM1 Signaling is Essential to Elicit Tim-3 Inhibitory Regulation in Liver Transplantation
The Dumont-UCLA Transplantation Center, Los Angeles, CA
*Purpose: T cell immunoglobulin domain and mucin domain-3 (TIM-3) has been reported to induce T cell exhaustion. By alleviating hepatic ischemia-reperfusion injury, we have explored…2021 American Transplant Congress
Transplanting Hepatitis C Infected Organs Into Uninfected Recipients: A Pharmacy Perspective
University of Alabama at Birmingham Hospital, Birmingham, AL
*Purpose: Due to direct acting antivirals (DAAs), hepatitis C virus (HCV) positive patients are now resources for organ transplantation in HCV negative recipients. Our institution…2021 American Transplant Congress
Tubastatin-a Mediated Protection from Liver Injury is Preserved in a Lymphocyte Deficient Model
1University of Pennsylvania, Philadelphia, PA, 2University of Illinois at Chicago, Chicago, IL
*Purpose: Liver Ischemia reperfusion injury (IRI) and Acetaminophen (APAP) toxicity are important causes of acute liver failure in the United States, that lack effective therapy.…2021 American Transplant Congress
Evaluation of High-versus Low-Dose Valganciclovir for Cytomegalovirus Prevention in Adult Liver Transplant Recipients: A Single Center Experience
*Purpose: Cytomegalovirus (CMV) is the most common infection after solid organ transplantation and is associated with increased morbidity and mortality. CMV prophylaxis is widely considered…2021 American Transplant Congress
Longitudinal Quality of Life Assessment in Liver Transplant – Feasibility Study and Early Results
Northwestern University, Chicago, IL
*Purpose: In addition to survival, quality of life (QoL) is critical to optimizing care in liver transplantation (LT). Although QoL is associated with clinical outcomes…2021 American Transplant Congress
Immunotherapy of Dc-cik Cells in Patient with Hepatocellular Carcinoma Recurrence Following Liver Transplantation
China Medical University Hospital, Taichung, Taiwan
*Purpose: Dendritic cells (DCs) and cytokine-induced killer (CIK) cells, components of anti-cancer therapy, have shown clinical benefits and potential to overcome chemotherapeutic resistance in some…2021 American Transplant Congress
Geographic Divergence in Waitlist Registration and Trends in Waitlist Removal for Liver Transplantation in Patients with Nonalcoholic Steatohepatitis (NASH)
*Purpose: This study aims to evaluate regional trends of waitlist (WL) registrations and removal for liver transplantation (LT) among United States (US) adults listed for…2021 American Transplant Congress
Adults Undergoing First Time Liver Transplantation with Biliary Atresia: An Analysis of the United Network for Organ Sharing Database
*Purpose: Although biliary atresia (BA) is the most common indication for liver transplantation in children, there is no published data on outcomes for individuals who…2021 American Transplant Congress
Validation of a Novel Gene Expression Biomarker of Rejection Following Liver Transplantation
*Purpose: Non-invasive biomarkers distinguishing early signs of immune activation vs. quiescence could more objectively guide immunosuppression management after liver transplantation (LT). Our aim was to…2021 American Transplant Congress
Clinical Correlation of Frailty Measures and Evaluation of Complementary Molecular Frailty Biomarker Candidates in a Prospective National Cohort of Liver Transplant Candidates
*Purpose: Frailty is a clinical condition characterized by a loss of physiologic reserve and increased susceptibility to stressors. Molecular frailty biomarkers may reflect the dysregulation…
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