Articles tagged "Liver transplantation"

2021 American Transplant Congress
Incidence of Pancreatic Exocrine Insufficiency in Patients Undergoing Liver Transplantation
J. Klein¹, M. Rangel¹, I. Ifearulundu¹, Y. Gely¹, Z. Spigel², S. Janardhan³, M. Hertl¹, E. Chan¹
¹Surgery, Rush University Medical Center, Chicago, IL, ²Surgery, Allegheny Health Network, Pittsburgh, PA, ³Hepatology, Rush University Medical Center, Chicago, IL
*Purpose: The purpose of this study was to determine the incidence of Pancreatic Exocrine Insufficiency (PEI) in patients undergoing liver transplantation. Furthermore, patient-specific risk factors…
2021 American Transplant Congress
Impact of Social Support, Social Circumstances and Distance from Transplant Center on Post Liver Transplant Outcomes: An Analysis from a Predominantly Rural U.S. Cohort
R. Kaur¹, C. Lavender¹, E. Askew¹, S. Jafri², R. Thandassery¹, M. Deneke¹
¹University of Arkansas for Medical Sciences, Little Rock, AR, ²Henry Ford Hospital, Detroit, MI
*Purpose: Social support and social circumstances (SSSC) are critical yet less described entities in post-orthotopic liver transplant (OLT). We aimed to describe SSSC and correlate…
2021 American Transplant Congress
Quantifying the Interaction Between Posaconazole and Tacrolimus in Liver Transplant Recipients: A Practical Approach
B. Lane¹, U. Kaszubski¹, A. Freeman¹, B. Wise¹, L. Hutchinson¹, M. Janusek¹, G. Therapondos², H. Bohorquez³, S. Anders¹
¹Pharmacy, Ochsner Medical Center, New Orleans, LA, ²Hepatology, Ochsner Medical Center, New Orleans, LA, ³Transplant Surgery, Ochsner Medical Center, New Orleans, LA
*Purpose: The interaction between tacrolimus (FK) and posaconazole (POSA) is well documented, however the extent of this interaction and the practical management has yet to…
2021 American Transplant Congress
Excellent Pathological Response with Gemcitabine-based Protocol in Patient with Hilar Cholangiocarcinoma
A. Saharia¹, R. McMillan¹, S. Kodali¹, M. Javley², C. M. Mobley¹, M. J. Hobeika¹, A. Shetty¹, D. W. Victor¹, R. McFadden¹, M. Abdelrahim¹, K. Heyne¹, A. O. Gaber¹, R. M. Ghobrial¹
¹Houston Methodist Hospital, Houston, TX, ²MD Anderson Cancer Center, Houston, TX
*Purpose: The standard treatment for hilar cholangiocarcinoma is using 5FU along with brachytherapy and external beam radiation. The downside of this regimen is the uncertain…
2021 American Transplant Congress
Pre-transplant Prognostic  Nutritional  Index  Predicts  Short-term  Outcomes  After  Liver Transplantation
E. Lisznyai, T. Kitajima, K. Delvecchio, A. Mohamed, S. Yeddula, T. Shamaa, T. Ivanics, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai
Transplant Institute, Henry Ford Hospital, Detroit, MI
*Purpose: To understand the importance of pre-transplant nutritional status in optimizing liver transplant outcomes.*Methods: The prognostic nutritional index (PNI) is a  serum  marker of nutrition…
2021 American Transplant Congress
Paired Surveillance Biopsies Over >4 Years from a Multi-Center Cohort of 78 Long-Term Pediatric Liver Transplant Recipients
E. R. Perito¹, E. Persyn², J. Bucuvalas³, J. E. Squires⁴, M. Martinez⁵, S. Mohammad⁶, A. J. Demetris⁴, S. Feng¹
¹UCSF, San Francisco, CA, ²King's College, London, United Kingdom, ³Mt. Sinai School of Medicine, NY, NY, ⁴U of Pittsburgh, Pittsburgh, PA, ⁵Columbia U, NY, NY, ⁶Northwestern U, Chicago, IL
*Purpose: Progressive liver fibrosis threatens graft and patient longevity for children after liver transplantation (LT). Previous studies are limited to single-center, cross-sectional analyses. To address…
2021 American Transplant Congress
Effects of Timing of Everolimus Transition on Renal Outcomes in Liver Transplant Recipients
M. Leick¹, H. Belleau², T. McCashland³
¹Nebraska Medicine, Omaha, NE, ²Bryan Health, Lincoln, NE, ³University of Nebraska Medical Center, Omaha, NE
*Purpose: The purpose of this study is to evaluate the effects of the timing of everolimus transition on renal outcomes in liver transplant recipients.*Methods: This…
2021 American Transplant Congress
Cytomegalovirus (CMV) D+/R- Serostatus is Independently Associated with Mortality and Graft Loss After Liver Transplantation (LTx)
P. Vutien, J. Perkins, S. Biggins, J. Reyes, A. Limaye
Internal Medicine, University of Washington Medical Center, Seattle, WA
*Purpose: It is unknown if donor or recipient (D/R) CMV serostatus, in the era of CMV prophylactic and pre-emptive strategies, remains associated with clinical outcomes…
2021 American Transplant Congress
Role of Ferroptosis Inhibitors in Mitigating Ischemia-Reperfusion Injury in Marginal Livers Using a Novel Protect Model
M. D. Nazzal, J. Van Nispen, A. Armstrong, V. Murali, E. Song, M. Voigt, A. Samaddar, E. Madsen, C. Manithody, J. Krebs, D. Blackall, D. Carpenter, C. Varma, J. Teckman, A. Jain
Saint Louis University, Saint Louis, MO
*Purpose: The discard rate of deceased donor livers (DDL) remains high at nearly 9% and incudes livers that are steatotic, old in age, and from…
2021 American Transplant Congress
Long Term Survival After Liver Transplantation for Advanced, Unresectable Intrahepatic Cholangiocarcinoma
R. R. McMillan¹, S. Kodali¹, M. Javle², A. Saharia¹, C. M. Mobley¹, M. J. Hobeika¹, A. Shetty¹, D. W. Victor¹, R. McFadden¹, M. Abdelrahim¹, K. Heyne¹, A. O. Gaber¹, R. M. Ghobrial¹
¹Houston Methodist Hospital, Houston, TX, ²MD Anderson Cancer Center, Houston, TX
*Purpose: Intrahepatic cholangiocarcinoma (ICCA) has traditionally been considered a contraindication to liver transplantation (LT). We previously reported a case series of six patients with large,…