Articles tagged "Liver transplantation"

2022 American Transplant Congress
Factors Predicting Early Extubation After Liver Transplantation
V. Subramanian¹, O. Bishr², J. Buggs¹, N. Kemmer¹, K. Dhanireddy¹
¹Transplant Institute, Tampa General Hospital, Tampa, FL, ²University of South Florida, Tampa, FL
*Purpose: Early extubation (either intraoperative or within 6 hours post operatively) is an important component of enhanced recovery pathways. The goal of the study was…
2022 American Transplant Congress
Center-Level Variation in Transplantation Practice Following Acuity Circles Policy Change
A. Burton¹, D. Goldberg²
¹University of Miami Miller School of Medicine, Miami, FL, ²Department of Gastroenterology, University of Miami Miller School of Medicine, Miami, FL
*Purpose: Although early studies suggest that the Acuity Circles (AC) allocation policy has reduced disparities in access to deceased donor liver transplants (DDLTs), changes in…
2022 American Transplant Congress
Meld Score <31 Predicts Spontaneous Recovery in Patients Listed for Liver Transplantation for Alcohol-Associated Hepatitis: A UNOS Database Study
Y. Bekki, G. Im, T. Schiano, S. Florman
Icahn School of Medicine at Mount Sinai, RMTI, New York, NY
*Purpose: Alcohol-associated hepatitis (AH) is the fastest growing indication for liver transplantation (LT) in the U.S. While spontaneous recovery (SR) can occur in patients with…
2022 American Transplant Congress
Artificial Intelligence Based Dosing of Tacrolimus in Liver Transplantation: Prospective, Randomized Phase 2 Trial
A. Zarrinpar¹, C. Ho², C. Warren¹, J. Khong², M. Lee², S. Duarte¹, K. Andreoni¹, M. Johnson¹, N. Battula³, D. McKimmy¹, T. Beduschi¹
¹Surgery, University of Florida, Gainesville, FL, ²Mechanical and Aerospace Engineering, University of California, Los Angeles, CA, ³Surgery, University of Oklahoma, Oklahoma City, OK
*Purpose: Inter- and intra-individual variability in calcineurin dose requirements necessitates empirical clinician-titrated dosing that frequently results in deviation from target ranges, particularly during the critical…
2022 American Transplant Congress
Post-Operative Day 1 Galectin-3 is Predictive of Early Allograft Dysfunction in Liver Transplantation
D. Yoeli, T. Ferrell, I. Rodriguez, N. Limon De La Rosa, N. Nakra, Z. Wang, E. Cervantes-Alvarez, R. Choudhury, M. Adams, T. Nydam, E. Pomfret, C. Huang, N. Navarro Alvarez, H. Moore
University of Colorado Anschutz Medical, Aurora, CO
*Purpose: Early allograft dysfunction (EAD) is an important outcome measure in liver transplantation that is predictive of graft failure, but the mechanism behind it remains…
2022 American Transplant Congress
Detection of Early Graft Injury After Liver Transplantation with Blood-Bile Ratio of Tacrolimus: The TUBE Trial
M. M. Pascale¹, G. Bianco¹, L. Ferri¹, F. Giovinazzo¹, A. Liguori², G. Marrone², A. Grieco², S. Agnes¹
¹General Surgery and Liver Transplant Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy, ²Transplant Hepatology Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy
*Purpose: The aim of the“Tacrolimus in Bile”(TUBE)Trial is the creation of a laboratory parameter for the early detection of hepatic injury after liver transplant.*Methods: TUBE…
2021 American Transplant Congress
Mortality, Risk Factors, and Treatment of Covid-19 Infection in Solid Organ Transplants: A Systematic Review and Meta-analysis
S. Yin, T. Song, Q. Zhong, T. Lin
Urology Institute and Organ Transplantation Center, West China Hospital, Chengdu, China
*Purpose: Outcomes for solid organ transplants (SOT) with COVID-19 have not been summarized, and prognostic factors for COVID-19 in SOT patients are not well established…
2021 American Transplant Congress
Systematic Implementation of Alcohol Screening Program Using Urine Ethyl Glucuronide Can Identify Post-transplant Alcohol Use and Aid Return to Sobriety in Liver Transplant Recipients
N. Lim¹, T. Leventhal¹, M. Thomson¹, M. Hassan¹, J. Thompson¹, S. Chinnakotla², V. Kirchner², T. Pruett¹, R. Kandaswamy², V. Humphreville², A. Adams², J. Lake¹
¹Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, ²Division of Transplantation, University of Minnesota, Minneapolis, MN
*Purpose: Rates of liver transplantation (LT) for alcohol-related liver disease (ALD) are increasing, particularly in patients with acute alcoholic hepatitis. Post-LT alcohol (ETOH) use has…
2021 American Transplant Congress
Are All DSA’s the Same? Are We Ready for Precision Medicine in Pediatric LT?
S. E. Shin¹, M. Lee¹, N. Yazigi², K. Khan², S. Kaufman², J. Ahn³, O. Timofeeva⁴, U. Ekong²
¹Georgetown University School of Medicine, Washington, DC, ²Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC, ³Biostatistics, Bioinformatics, & Biomathematics, Georgetown University, Washington, DC, ⁴Histocompatibility Laboratory, Dept. of Pathology & Laboratory Medicine, Georgetown University, Washington, DC
*Purpose: Donor-specific antibodies (DSA) play an uncertain role in rejection after liver transplantation (LT). We hypothesized that evaluation of epitope differences in HLA-DR/DQ mismatching can…
2021 American Transplant Congress
Liver Transplantation for COVID-19-associated Cholangiopathy
J. Blondeel¹, P. Meersseman², N. Gilbo¹, I. Jochmans¹, M. Sainz-Barriga¹, J. Pirenne¹, D. Monbaliu¹
¹Abdominal Transplantation Surgery, University Hospitals Leuven, Leuven, Belgium, ²Medical Intensive Care Unit, University Hospitals Leuven, Leuven, Belgium
*Purpose: The hallmark viral pneumonia of coronavirus-19-disease (COVID-19) is often accompanied by important extra-pulmonary manifestations. Liver dysfunction occurs in up to 45% of COVID-19 patients,…