2022 American Transplant Congress
PACAP-Mediated Autophagy Prevents Liver Ischemia Reperfusion Injury in OLT
UCLA Medical Center, Los Angeles, CA
*Purpose: Pituitary adenylate cyclase-activating polypeptide (PACAP) is from vasoactive intestinal peptide-glucagon-secretin family. Our group was the first to demonstrate that neuropeptide PACAP, which innervates the…2022 American Transplant Congress
A Successful Expansion of Donor Liver Supply is Feasible with the Selective Use of Older DCD Livers
Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX
*Purpose: DCD are a key way to expand the donor pool, yet many centers are hesitant about using anything but the most favorable DCD allografts,…2022 American Transplant Congress
Race Inequity in Liver Transplant Waitlisting: Effect Modification by Psychosocial Factors and the Stanford Integrated Psychosocial Assessment for Transplant
*Purpose: Race inequity in liver transplantation (LT) has been a longstanding area of injustice within the field of hepatology. Information from psychosocial evaluations and The…2022 American Transplant Congress
Liver Transplantation Outcomes for Budd-Chiari Syndrome in the MELD Era
*Purpose: Budd Chiari syndrome (BCS) has a heterogeneous clinical presentations ranging from asymptomatic cases to fulminant liver failure with significant morbidly and mortality. Recent data…2022 American Transplant Congress
A Intention-to-Treat Analysis of 881 Consecutively Waitlisted Patients to Develop a Survival Benefit Model for Hepatocellular Carcinoma Liver Transplant Candidates
*Purpose: The current liver transplantation (LT) selection paradigm for hepatocellular carcinoma (HCC) patients ignores the variable risks of waitlist dropout and post-LT recurrence/death, with the…2022 American Transplant Congress
Telemedicine Implementation in Solid Organ Transplant (SOT) Clinics is Associated with Satisfaction Among Patients and Providers but Increased Burden on Staff
University of California, San Francisco, San Francisco, CA
*Purpose: Telemedicine is an essential part of healthcare delivery and has grown exponentially during the COVID-19 pandemic. Data on optimal utilization and implementation of telemedicine…2022 American Transplant Congress
Ikaros-SIRT1 Signaling Axis Regulates Macrophage Pyroptosis and Ischemia-Reperfusion Injury (IRI) in Mouse and Human Liver Transplantation
1UCLA Medical Center, Los Angeles, CA, 2NIEHS, Durham, NC
*Purpose: Although Ikaros is a well-established regulator of lymphopoiesis, its role in myeloid cells and organ IRI remains unclear. We recently reported that the SIRT1-mediated…2022 American Transplant Congress
Temporal Changes in the Peripheral Immune Profile of Acute Rejection Highlight New Mechanisms of Alloimmunity and Potential Non-Invasive Biomarkers of Rejection in Pediatric Liver Transplantation
*Purpose: Acute rejection (AR) is common in pediatric liver transplantation (LT) and can impact late graft loss. Immune subpopulations mediating AR in LT have not…2022 American Transplant Congress
Revisiting Late Graft Loss or Death in Pediatric Liver Transplantation Through Analysis of the SPLIT Database
*Purpose: With advances in surgical techniques, medical management, and more equitable allocation systems, children who receive a liver transplant today can expect remarkable outcomes early…2022 American Transplant Congress
Reality Capture Using Light Detection and Ranging 3D Photography of Liver Grafts for Volumetric Assessment: A Proof-of-Concept Preliminary Study
*Purpose: Reality capture uses various technical means to capture a digital 3D model representation of a subject from the real world. Whole liver graft volume…
American Transplant Congress abstracts