ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2015 American Transplant Congress

    Tandem P-Selectin Glycoprotein Ligand-Immunoglobulin (TSGL-Ig) Protects Liver Endothelial Cells Against Prolonged Cold Preservation Injury in Mouse Liver Transplantation

    C. Zhang,1 H. Ji,1 Y. Liu,1 X. Shen,1 F. Gao,1 R. Busuttil,1 G. Shaw,2 J. Kupiec-Weglinski.1

    1Dept of Surgery, Dumont-UCLA Liver Transplant Center, Los Angeles, CA; 2Quell Pharma Inc., Half Moon Bay, CA.

    Background: Liver endothelial cell (LEC) damage is central in the pathogenesis of hepatic ischemia-reperfusion injury (IRI). LEC detachment/progressed denudation are typical during cold storage and…
  • 2015 American Transplant Congress

    Adoptive Immunotherapy With Liver Allograft-Derived NK Cells Improves Recurrence-Free Survival After Living-Donor Liver Transplantation in Patients With Hepatocellular Carcinoma

    N. Tanimine, Y. Tanaka, K. Ishiyama, M. Ohira, S. Shimizu, T. Yano, H. Ohdan.

    Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.

    Introduction: Previous studies revealed that the recurrence rate of hepatocellular carcinoma (HCC) was still 10–20%, even among liver transplantation (LT) recipients meeting the Milan criteria…
  • 2015 American Transplant Congress

    Regional Variations: Liver Transplant Tourism Within the US

    C. Frenette,1 A. Harper,2 R. Schaffer,1 J. Fisher,1 A. Baquerizo,1 C. Marsh.1

    1Department of Organ Transplantation, Scripps Clinic/Green Hospital, La Jolla, CA; 2United Network for Organ Sharing, Richmond, VA.

    Aim: Given the current geographic disparities in average MELD scores at liver transplantation (OLT), there is increasing interest in patients who travel for OLT and…
  • 2015 American Transplant Congress

    End of Treatment Liver Biopsy With Sofosbuvir: Histologic Changes Suggestive of Hepatitis C Activity in Liver Transplant Recipients With Achieved SVR

    B. Ismail,1 X. Zervos,1 P. Bejarano,2 M. Waton,1 D. Beltran,3 D. Sears,1 A. Tzakis.1

    1Liver Transplant, Cleveland Clinic Florida, Weston, FL; 2Pathology, Cleveland Clinic Florida, Weston, FL; 3Pharmacy, Cleveland Clinic Florida, Weston, FL.

    Background: Interferon (IFN) free HCV regimens are associated with better tolerability and efficacy. The majority of studies report biochemical and virological response; however limited information…
  • 2015 American Transplant Congress

    Improved Renal Function Post-Liver Transplant With Earlier Everolimus Conversion

    S. Lin,1 M. Zimmerman,2 V. Lewis,1 S. Biggins,3 C. Ruller,4 I. Kam,4 T. Nydam.4

    1Pharmacy Dept, University of Colorado Hospital, Aurora; 2Division of Transplant Surgery, Medical College of Wisconsin, Wisconsin; 3Division of Gastroenterology/Hepatology, University of Colorado, Aurora; 4Division of Transplant Surgery, University of Colorado, Aurora.

    Calcineurin inhibitors (CNI) play an important role in preventing acute rejection (AR) post-liver transplant. Its long-term use is limited by development of nephrotoxicity. Optimal timing…
  • 2015 American Transplant Congress

    Comparison of Renal Outcomes for Liver Transplant Recipients With Pretransplant Renal Dysfunction Receiving Sirolimus Or Tacrolimus With Rabbit Antithymocyte Globulin Induction

    B. Duhart,1 W. Ally,2 V. Rao,3 A. Krauss,4 J. Eason,3 J. Vanatta.3

    1University of Tennessee College of Pharmacy, Memphis, TN; 2Pharmacy, University of Virginia Medical Center, Charlottesville, VA; 3Surgery, Methodist University Hospital Transplant Institute/University of Tennessee Health Science Center, Memphis, TN; 4Pharmacy, Methodist University Hospital, Memphis, TN.

    Published data are limited describing renal outcomes in orthotopic liver transplant (OLT) recipients prescribed de novo sirolimus (SRL) maintenance immunosuppression and rabbit antithymocyte globulin (rATG).…
  • 2015 American Transplant Congress

    The Impact of CDC High Risk Donors on Patient and Graft Survival After Liver Transplantation

    D. Moonka, A. Yoshida, A. Taylor.

    Division of Gastroenterology, Henry Ford Health System, Detroit, MI; Transplant Institute, Henry Ford Health System, Detroit, MI; Department of Public Health Sciences, Henry Ford Health System, Detroit, MI.

    We hypothesized that CDC high risk donors (HRD) might be younger than non-HRD and have other characteristics associated with favorable outcomes after liver transplant (LT).…
  • 2015 American Transplant Congress

    Single-Center Analysis of Adult, Combined Heart-Liver Transplant (CHLT) Recipients

    H. Monsour Jr,1 M. Boktour,2 A. Abimbola,1 M. Elnemr,1 S. Gordon Burroughs,2 D. Victor III,1 A. Saharia,2 B. Trachtenberg,3 A. Bhimaraj,3 A. Gaber,2 J. Estep,3 R. Ghobrial.2

    1Department of Medicine, Houston Methodist Hospital, Houston, TX; 2Department of Surgery, Houston Methodist Hospital, Houston, TX; 3Cardiology Department, Houston Methodist Hospital, Houston, TX.

    Background: Combined heart-liver transplantation (CHLT) is life-saving for patients with end-stage heart-liver diseases. This is a review of patients who underwent CHLT at a single-center.Methods:…
  • 2015 American Transplant Congress

    Identification of miRNAs Associated With Induced Tolerance to Allografts

    M. Vitalone, L. Wei, C. Esquivel, S. Busque, O. Martinez, S. Krams.

    Surgery-Transplantation, Stanford University School of Medicine, Stanford, CA.

    Introduction: Although the liver is less immunogenic than other solid organs, most liver transplant recipients receive lifelong immunosuppression. Total lymphoid irradiation (TLI) is part of…
  • 2015 American Transplant Congress

    SBRT(Stereotactic Body Radiotherapy) to Bridge or Down-Size HCC for Liver Transplantation

    N. Thai,1 K. Tom,1 M. Szramowski,1 P. Abrams,1 J. Oliva,3 D. Monga,4 M. Raj,4 D. Parda,2 A. Kirichenko.2

    1Transplant Surgery, Allegheny Health Network, Pittsburgh, PA; 2Radiation Oncology, Allegheny Health Network, Pittsburgh, PA; 3Hepatology, Allegheny Health Network, Pittsburgh, PA; 4Medical Oncology, Allegheny Health Network, Pittsburgh, PA.

    Twenty seven (27) pts with HCC and cirrhosis have been treated with SBRT with intent for liver transplantation since 2010 at Allegheny Health Network. Nineteen…
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