ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2015 American Transplant Congress

    Epidemiology of Pneumonia in a Cohort of 5,000+ Abdominal Solid Organ Transplant Recipients

    A. Masica, S. Delcroix-Lopes, M. Kouznetsova, C. Spak.

    Baylor Scott & White Health, Dallas, TX.

    Study purposeWe evaluated the epidemiology of pneumonia (PNE) in a longitudinal cohort of patients with abdominal (kidney, liver, and/or pancreas) solid organ transplants (SOT).MethodsRetrospective study…
  • 2015 American Transplant Congress

    Refinement of Non-Invasive Diagnostic Criteria to Differentiate Tumor from Bland Portal Vein Thrombosis Before Liver Transplant in Patients With Hepatocellular Carcinoma

    C. Sherman, S. Behr, J. Dodge, J. Roberts, F. Yao, N. Mehta.

    University of California San Francisco, San Francisco, CA.

    Differentiating tumor vs bland portal vein thrombosis (PVT) is essential in determining liver transplant (LT) candidacy for patients with hepatocellular carcinoma (HCC). The primary aim…
  • 2015 American Transplant Congress

    Small RNA Sequencing-Enabled Discovery of Circulating Extracellular MicroRNAs as Noninvasive Biomarkers of Liver Allograft Status

    H. Yang,1 T. Muthukumar,1 K. Akat,2 D. Briskin,2 T. Tuschl,2 M. Suthanthiran.1

    1Weill Cornell Medical Center, New York; 2Rockefeller University, New York.

    MicroRNAs are ideal candidates as blood-based biomarkers. Comprehensive profiling of microRNAs is challenging. We overcame the existing challenges by developing robust protocols for isolation of…
  • 2015 American Transplant Congress

    Outcomes of Hepatitis C Virus (HCV) Treatment Following Liver Transplantation in the Era of Direct-Acting Antiviral Medications

    S. Baggett,1 D. Jones,1 M. Shoreibah.2

    1Department of Pharmacy, UAB Hospital, Birmingham, AL; 2Department of Gastroenterology, UAB Hospital, Birmingham, AL.

    BACKGROUND: The treatment of HCV is one of the most rapidly changing areas of medical practice. These agents have been shown to be safe and…
  • 2015 American Transplant Congress

    Everolimus-Based Immunosuppression Is Associated With a Reduced Risk of New-Onset Malignancies After Liver Transplantation

    P. De Simone,1 P. Carrai,1 L. Coletti,1 D. Ghinolfi,1 D. Campani,2 F. Filipponi.1

    1Hepatobiliary Surgery and Liver Transplantation, University of Pisa Medical School Hospital, Pisa, Italy; 2Pathology, University of Pisa Medical School Hospital, Pisa, Italy.

    Background and aim: The inhibitor of the mammalian target of rapamycin (mTOR) everolimus (EVR) has shown anti-proliferative effects in experimental and clinical models. We investigated…
  • 2015 American Transplant Congress

    Risk of End-Stage Renal Disease After Living Donor Liver Transplantation: Overall Incidence and Comparisons to Deceased Donor Recipients

    D. Goldberg,1 R. Ruebner,2 P. Abt.3

    1Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA; 2Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA; 3Department of Surgery, University of Pennsylvania, Philadelphia, PA.

    Introduction: Since initiation of MELD-based allocation for liver transplants, the risk of end-stage renal disease (ESRD) post-liver transplantation has increased. Recent US data demonstrated comparable,…
  • 2015 American Transplant Congress

    The Predictive Value of the Proliferation Marker Ki-67 in Patients With Fulminant Hepatic Failure

    A. Shah,1 U. Joneja,2 D. Walls,1 J. Farber.2

    1Surgery, Thomas Jefferson University, Philadelphia, PA; 2Pathology, Thomas Jefferson University, Philadelphia, PA.

    This study aimed to evaluate the prognostic significance of the cellular proliferation marker Ki-67 in the liver biopsies of patients with fulminant hepatic failure.Under IRB…
  • 2015 American Transplant Congress

    Use of MELD Exception Points in Patients With Hepatic Neuroendocrine Tumor Metastases: Variable Use and Proposed Criterion for Approval

    Y. Nobel,1 D. Goldberg.2,3,4

    1Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; 2Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, PA; 3Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; 4Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA.

    Purpose: Most patients with metastatic neuroendocrine tumors (NETs) have preserved hepatic synthetic function, and their providers may seek increased waitlist priority via MELD exception points.…
  • 2015 American Transplant Congress

    Cost-Effective, Simple PTC Tasting Could Be a Useful Adjunct to Selection Criteria of ARLD Patients

    K. Bortecen,1 D. Freitas,1 C. Teperman,2 M. Hamshow,1 B. Gelb,1 G. Morgan,1 L. Teperman.1

    1Transplant Surgery, NYU Langone Medical Center, The Mary Lea Johnson Richards Organ Transplant Center, New York, NY; 2Columbia Prep School, New York, NY.

    Purpose: Phenylthiocarbamide (PTC) tasting has been linked to alcohol use. The bitter taste for PTC is mediated by TAS2R38 gene. We have previously shown individuals…
  • 2015 American Transplant Congress

    Liver Transplantation for Primary Liver Malignancies Vs. Neuroendocrine Metastases: Analysis of the UNOS Dataset

    V. Vilchez,1 M. Shah,1 M. Daily,1 S. Krohmer,2 D. Davenport,1 E. Maynard,1 R. Gedaly.1

    1Department of Surgery - Transplant Section, University of Kentucky, Lexington, KY; 2Department of Radiology, University of Kentucky, Lexington, KY.

    Objective: To determine outcome in patients undergoing LT for NETs, and compared them with outcomes in patients with primary liver malignancies such as Hepatocellular Carcinoma…
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