ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2015 American Transplant Congress

    Hospital Characteristics Mediate Variation in Cirrhosis Mortality in Transplant and Non-Transplant Facilities

    A. Mathur,1 A. Chakrabarti,2 K. Sheetz,2 J. Mellinger,3 M. Volk,3 N. Katariya,1 A. Singer,1 W. Hewitt,1 K. Reddy,1 A. Moss.1

    1Surgery, Mayo Clinic Arizona, Phoenix, AZ; 2Surgery, University of Michigan, Ann Arbor, MI; 3Medicine, University of Michigan, Ann Arbor, MI.

    Hospitals vary significantly in cirrhosis mortality. We aimed to determine whether hospital structural characteristics mediate this effect.Methods: We used 2009 data from the HCUP Nationwide…
  • 2015 American Transplant Congress

    Renal Function Difference Between Anti-Hepatitis B Immunoglobulin(HBIG) Monotherapy and HBIG Combined With Entecavir in Liver Recipients

    J. Lee,1,2 J. Lee,1,2 J. Lee,3 M. Kim,1,2 M. Ju,1,2 G. Choi,1,2 J. Choi,1,2 S. Kim,1,2 D. Joo.1,2

    1Department of Transplantation Surgery, Severance Hospital, Yonsei University Health System, Seroul, Korea; 2Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; 3Department of Surgery, CHA Bundang Medical Center, CHA University, Bundang, Korea.

    Background: To reduce the HBV reinfection after liver transplantation, anti-hepatitis B immunoglobulin (HBIG) alone or combination with antiviral nucleotide analogues are usually used regimen. However,…
  • 2015 American Transplant Congress

    National Outcomes of Donation After Cardiac Death (DCD) Liver Transplantation Are Equivalent to Donation After Brain Death (DBD) Liver Transplantation Using Older (DBD) Donor Livers

    R. Redfield, M. Rizzari, J. Scalea, L. Fernandez, A. D'Alessandro, J. Mezrich, D. Foley.

    University of Wisconsin, Madison, WI.

    Background: Multiple studies have demonstrated that outcomes of DCD liver transplantation (LTx) are inferior to DBD LTx. Thus DCD liver transplantation represents only 7% of…
  • 2015 American Transplant Congress

    Donor Hemodynamic Profile Presages Graft Survival in Donation After Cardiac Death Liver Transplantation

    M. Ertreo, C. Desai, R. Girlanda, T. Frias, T. Fishbein.

    Transplant Institute, Georgetown University Hospital, Washington, DC.

    IntroductionDonation after cardiac death (DCD) grafts are prone to periods of prolonged hypoxemia and hypotension prior to donor expiration, leading to an increased complication rate,…
  • 2015 American Transplant Congress

    The Utility of Non-Invasive Intra Abdominal Pressure Monitoring After Pediatric Abdominal Organ Transplantation

    E. Harkin,1 M. McLeod,1 K. Khan,2 A. Natarajan.3

    1Pediatrics, Georgetown University School of Medicine, Washington, DC; 2Georgetown Transplant Institute, MedStar-Georgetown University Hospital, Washington, DC; 3Pediatrics, Pharmacology and Physiology, MedStar-Georgetown University Hospital, Washington, DC.

    Intra abdominal pressure (IAP) is monitored in critically ill children because intra-abdominal hypertension (IAH) may be associated with renal dysfunction and adverse outcomes.We retrospectively examined…
  • 2015 American Transplant Congress

    Verification of OPTN Hepatocellular Carcinoma Recurrence Data

    J. George,1 K. Eddinger,1 D. Goldberg,2 M. Levine,3 P. Abt.3

    1Perelman School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA; 2Division of Gastroenterology, Hospital of the University of Pennsylvania, Philadelphia, PA; 3Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA.

    PURPOSE: OPTN data on HCC recurrence is increasingly utilized for a variety of studies; however, the accuracy of this data has not been examined. We…
  • 2015 American Transplant Congress

    Early Allograft Dysfunction Causes Inferior Patient and Allograft Survival in Liver Transplantation; an Experience of 1952 Consecutive Liver Transplants

    D. Lee, K. Croome, J. Burns, D. Perry, J. Nguyen, H. Crespo, C. Taner.

    Transplantation, Mayo Clinic, Jacksonville, FL.

    Background: Early allograft dysfunction (EAD) in liver transplantation (LT) is a useful intermediate outcome measure to predict graft loss or mortality. We sought to investigate…
  • 2015 American Transplant Congress

    The Impact of the New Antivirals Sofosfuvir/Ledipasvir on Liver Transplantation for Hepatitis C Cirrhosis

    S. Munoz,1 D. Reich,2 K. Rothstein.1

    1Div of Hepatology, Liver Failure Unit, Hanemann University Hospital, Philadelphia, PA; 2Liver, Kidney and Pancreas Transplant Program, Hahnemann University Hospital, Philadelphia, PA.

    The approval of potent antiviral therapy (AVT) with sofosfuvir/ledipasvir (sof/ldv) for hepatitis C (HCV) dramatically increased cure rates (SVR) to nearly 100%. A recent prospective…
  • 2015 American Transplant Congress

    The Impact of Acute Rejection on Liver Transplant Survival in the New Millennium

    J. Levitsky,1 S. Forney,2 B. Gillespie,3 R. Merion,2,3 A. Lok,3 G. Levy,4 L. Kulik,1 M. Abecassis,1 A. Shaked.5

    1Northwestern U, Chicago, IL; 2Arbor Research Collaborative for Health, Ann Arbor, MI; 3U Michigan, Ann Arbor, MI; 4U Toronto, Toronto, ON, Canada; 5U Pennsylvania, Philadelphia, PA.

    Background: Based on pre-2000 data, acute rejection (AR) has long been considered clinically less significant in liver transplant (LT) vs. other organ recipients (Charlton et…
  • 2015 American Transplant Congress

    Donor Organ Resident M2 Type Myeloid Cells Protect Murine Orthotropic Liver Transplants from Ischemia and Reperfusion Injury

    S. Yue, X. Shen, F. Gao, R. Busuttil, J. Kupiec-Weglinski, Y. Zhai.

    The Dumont-UCLA Transplant Ctr., UCLA, Los Angeles, CA.

    Liver ischemia reperfusion injury (lRI) is mediated by a pro-inflammatory immune response initiated by the activation of liver non-parenchymal innate immune cells, such as Kupffer…
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