2016 American Transplant Congress
Role of Donor Hemodynamic Trajectory in Determining Graft Survival in Liver Transplantation from Donation After Circulatory Death Donors.
This retrospective study of 87 donation after circulatory death (DCD) liver transplants from 2007-2015 tested the hypothesis that donor hemodynamic trajectory following withdrawal effects graft…2016 American Transplant Congress
Thorough Pre-Transplant Evaluation and Appropriate Case Selection Is the Mainstay for Better Survival in Recipients with Malignancy.
IntroductionMalignancy has become one of the three major causes of death after transplantation in the past decade and is thus increasingly important in all organ…2016 American Transplant Congress
Predicting and Reducing 30-Day Readmission After Liver Transplant (OLT).
Transplant Surgery, Cleveland Clinic Foundation, Cleveland, OH.
Background:Reducing early readmissions is a challenge. This study aimed to identify predictors of 30-day readmissions and interventions to minimize readmissions.Methods: Records of 523 adult OLT…2016 American Transplant Congress
Resveratrol Attenuates Liver IRI by Regulating Macrophage Activation Through SIRT1/p19/p53 Pathway.
Background/Aim: Sirtuin1 (SIRT1), a NAD+-dependent type III histone/protein deacetylase, plays a key role in inflammation responses and stress resistance. Although SIRT1 may regulate innate activation…2016 American Transplant Congress
Ideal Outcome After Liver Transplantation: An Exploratory Study Using Machine Learning Analyses to Leverage Long-Term Registry Data from Studies in Pediatric Liver Transplantation (SPLIT).
We analyzed the Studies in Pediatric Liver Transplantation (SPLIT) registry dataset using heat map and random forests analyses (RFA) to determine if ideal outcome (IO)…2016 American Transplant Congress
Biopsy-Proven Rejection in Children After Liver Transplantation Is Associated by an IL-12p40-Mediated Innate Immune Response Followed by Th1 T Cell Activation.
Sustained by adaptive immune cells and their soluble mediators is well established for infection but it has not been demonstrated for solid organ transplantation in…2016 American Transplant Congress
The Finances of Broader Sharing of Livers Following Share 35.
Background. After implementation of the “Share 35” policy in 2013, many centers and OPOs reported increased costs associated with broader sharing. The OPTN Liver and…2016 American Transplant Congress
Pre-Transplant Loco-Regional Therapy for Hepatocellular Carcinoma and Post-Transplant Outcomes: A National Study.
1Saint Louis Univ, Saint Louis; 2East Carolina Univ, Greenville.
Currently most transplant centers use loco-regional therapy to bridge liver transplant (LT) candidates with hepatocellular carcinoma (HCC). However, limited data are available to support the…2016 American Transplant Congress
Hospitalizations for Cardiovascular Disease After Liver Transplantation in the United States: Epidemiology, Outcomes, and Costs.
Transplant Center, Mayo Clinic, Phoenix.
Background: Cardiovascular disease (CVD) is a leading cause of post-liver transplant death, and variable care patterns may affect outcomes. We aimed to describe epidemiology, outcomes,…2016 American Transplant Congress
Serelaxin Decreases the Severity of Cold Ischemia-Reperfusion Injury After Liver Transplantation in Mice.
The Dumont-UCLA Transplantation Center, UCLA, Los Angeles, CA.
Background. Extended cold preservation contributes to ischemia-reperfusion injury (IRI), which impairs graft function and leads to poor clinical outcomes. Serelaxin (SER), a recombinant form of…
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