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Articles tagged "Liver transplantation"

  • 2016 American Transplant Congress

    Results from 100 Consecutive Donation-After-Circulatory Death (DCD) Liver Transplants Using a Thrombolytic Protocol.

    J. Seal, H. Bohorquez, N. Battula, E. Ahmed, D. Bruce, I. Carmody, R. Trevor, G. Tyson, S. Joshi, N. Bzowej, G. Therapondas, N. Girgrah, A. Cohen, G. Loss.

    Multi-Organ Transplant Institute, Ochsner Clinic Foundation, New Orleans, LA.

    Background: In early 2010, our center implemented a thrombolytic protocol for DCD liver transplantation in an effort to reduce biliary complications and improve graft survival.…
  • 2016 American Transplant Congress

    Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) Protects Against Loss of Hepatic Integrity After Ischemia-Reperfusion Injury.

    T. Fujii, S. Duarte, R. Busuttil, A. Coito.

    Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA.

    Liver ischemia-reperfusion injury (IRI) remains a challenging problem in clinical orthotopic liver transplantation (OLT). Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix (ECM)-associated protein…
  • 2016 American Transplant Congress

    Cardiovascular Prognosis and Adverse Cardiac Events After Orthotopic Liver Transplantation.

    L. Potena, V. Manfredini, P. Prestinenzi, R. Alabrese, V. Bertuzzo, L. Borgese, M. Masetti, C. Morelli, F. Grigioni, A. Pinna.

    University of Bologna, Bologna, Italy.

    Cardiovascular (CV) disease is a major cause of morbidity and mortality among transplant candidate and recipients of noncardiac organs. Aiming to analyze the impact of…
  • 2016 American Transplant Congress

    Epidemiology of Surgical Site Infections After Liver Transplantation: 4 Year Prospective Study.

    Y. Natori, R. Kassar, A. Iaboni, S. Hosseini-Moghaddam, D. Vu, S. Husain, E. Renner, C. Rotstein.

    Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada.

    IntroductionDeceased and living donor liver transplantation (LT) is a lifesaving procedure for individuals with liver failure. However, despite the use of perioperative antibiotic prophylaxis at…
  • 2016 American Transplant Congress

    Long-Term Outcomes in Pediatric Live-Donor Liver Transplantation.

    N. Celik,1 A. Ganoza,2 F. Vyas,1 J. Squires,3 V. Venkat,3 G. Bond,1 K. Soltys,1 R. Sindhi,1 R. Squires,3 A. Humar,2 G. Mazariegos.1

    1Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Thomas E. Starzl Transplantation Institute, Department of Surgery at UPMC, Pittsburgh, PA; 3Division of Pediatric Gastroenterology, CHP of UPMC, Pittsburgh, PA.

    Aim: To determine the incidence of allograft and medical factors characterizing optimal patient outcomes 3 year or more after pediatric live-donor liver transplantation (LDLT). Methods:…
  • 2016 American Transplant Congress

    Tacrolimus Levels in Patients Treated with Direct Acting Antivirals Post-Transplant.

    J. Wiegel, T. Egbuka.

    Pharmacy, Oregon Health & Science University, Portland, OR.

    Purpose: To determine if treatment of recurrent hepatitis C virus (HCV) post-liver transplant with the direct-acting antivirals (DAAs) sofosbuvir, simeprevir, and ledipasvir (in combination and/or…
  • 2016 American Transplant Congress

    Hepatic Hemodynamics (HD) and Portal Flow Modulation (PM): Tactical Use in Small for Size (SFS) Live Donor Liver Transplantation (LDLT).

    T. Mansour,1 J. Pisa,1 E. Przybyszewski,1 J. Guarrera,1 K. Tomoaki,1 B. Samstein,1 K. Halazun,2 A. Griesemer,1 J. Emond.1

    1Surgery, Columbia University Medical Center, New York; 2Surgery, Weill Cornell Medical Center, New York.

    Objectives:Efforts to reduce the risk of donor hepatectomy have resulted in smaller grafts for transplantation. Grafts below 0.8% of recipient body weight (GW/RW), have been…
  • 2016 American Transplant Congress

    Early Post-Transplant Immunosuppression (IS) Withdrawal – Final Outcomes of the ITN030ST AWISH Study.

    A. Shaked,1 S. Feng,2 J. Punch,3 J. Reyes,4 J. Levitsky,5 G. Klintmalm,6 H. Kopetskie,7 M. DesMarais,2 A. Priore,8 N. Bridges,8 P. Sayre.2

    1UPenn, Philadelphia; 2UCSF, San Francisco; 3U Michigan, Ann Arbor; 4U Washington, Seattle; 5Northwestern, Chicago; 6Baylor, Dallas; 7RhoFed, Chapel Hill; 8NIAID, Bethesda.

    ITN030ST is a prospective randomized trial designed to determine the clinical benefit of early IS withdrawal in adult liver transplant (LT) recipients. Recipients did not…
  • 2016 American Transplant Congress

    Functional Status and Comorbidity Are Associated with High Costs After Liver Transplantation.

    M. Serper, M. Rossi, T. Bitterman, A. Shaked, K. Olthoff.

    University of Pennsylvania, Philadelphia.

    Purpose: The purpose of this study was to identify the clinical characteristics associated with high costs of liver transplantation (LT) at a large transplant center…
  • 2016 American Transplant Congress

    3D-FLM (First, Last, Max): A Novel Summative Measure of Hepatocellular Carcinoma (HCC) Tumor Burden Predicts HCC Recurrence After Liver Transplantation (LT).

    E. Nordstrom,1 J. Dodge,2 J. Gralla,1 K. Campbell,1 C. Palmer,1 S. Biggins.1

    1Univ. Colorado, Aurora; 2UCSF, San Francisco.

    Risk of recurrent HCC post-LT depends on tumor aggressiveness, pre-LT HCC burden and treatment response while waiting for LT. Standard measures of pre-LT HCC burden…
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