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American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2016 American Transplant Congress

    Strategies to Prevent Ischemic Cholangiopathy After Donation After Circulatory Death Donor Liver Transplantation.

    C. Kubal,1 R. Mangus,1 J. Fridell,1 B. Ekser,1 N. Rush,2 R. Saxena,2 J. Tector.1

    1Department of Surgery, Indiana University School of Medicine, Indianapolis, IN; 2Department of Pathology, Indiana University School of Medicine, Indianapolis, IN.

    Background: Donation after circulatory death (DCD) donor pool remains underutilized for liver transplantation (LT). We describe optimizing the “modifiable risk factors”, such as CIT, recipient…
  • 2016 American Transplant Congress

    Amino Acid (AA) Metabolism During Liver Allograft Preservation Comparing Subnormothermic Machine Perfusion (MP) Against Cold Storage (CS).

    B. Banan, R. Lopez, C. Hughes, G. Michalopoulos, P. Fontes.

    University of Pittsburgh, Pittsburgh.

    Introduction: Liver is the major site for nitrogen metabolism. Most hepatic transcriptional activity is related to protein-specific synthesis. Liver preservation has a direct impact in…
  • 2016 American Transplant Congress

    Outcomes of Anticoagulation Use for Portal Vein Thrombosis in University of Wisconsin Liver Transplant Patients.

    M. Falls,1 A. Said,2 L. Fernandez,2 D. Foley,2 K. Frith,1 D. Hager,2 H. Hoy,1 G. Leverson,2 J. Mezrich,2 T. Prickette,2 M. Wakefield,2 A. D'Alessandro.2

    1School of Nursing, University of Alabama, Huntsville, AL; 2Transplant Surgery, University of Wisconsin, Madison, WI.

    Background: The prevalence of Portal Vein Thrombosis (PVT) in cirrhotic liver transplant patients increases the risk of morbidity and mortality post-liver transplantation. Current research suggests…
  • 2016 American Transplant Congress

    Influence of Donor and Recipient CYP3A4, CYP3A5 and ABCB1 Genotypes on Outcomes in Liver Transplants.

    M. Debette-Gratien,1 J. Woillard,2 N. Picard,2 M. Sebbagh,4 D. Sautereau,5 V. Loustaud-Ratti,1 D. Samuel,3 P. Marquet.2

    1Hepatology, INSERM UMR 850, Univ Limoges, CHU Limoges, Limoges, France; 2Pharmacology and Toxicology, INSERM UMR 850, Univ Limoges, CHU Limoges, Limoges, France; 3Hepatology, INSERM U785, Centre hépatobiliaire, Villejuif, France; 4Hepatology, Centre Hépatobiliaire, Villejuif, France; 5Hepatology, CHU Limoges, Limoges, France.

    Liver transplantation is a life-saving technique for patients with end-stage liver disease. Pharmacogenetics is promising to explain a part of variability of calcineurin inhibitors efficacy…
  • 2016 American Transplant Congress

    Use of En-Bloc Vascularized Rectus Sheath Allograft to Achieve Abdominal Closure in Pediatric Liver and Multivisceral Transplantation.

    J. Reddy, A. Rege, D. Vikraman, B. Collins, T. Brennan, S. Knechtle, D. Sudan, K. Ravindra.

    Surgery, Duke University, Durham, NC.

    Background: Abdominal wall closure is often challenging in pediatric liver (LT) and multivisceral transplantation (MVT) due to size discrepancy of donor & recipient and abdominal…
  • 2016 American Transplant Congress

    Sofosbuvir-Based Regimen in Treatment Experienced-Post Liver Transplant Patients with Hepatitis C Recurrence.

    A. Ajlan,1 A. Aljedai,1 H. Elsiesy,2 D. Alkortas,1 R. Alarieh,2 W. Alhumodi,2 D. Broring,2 M. Alsebayel,2 F. Aba Alkhail.2

    1Pharmaceutical Care, KFSHRC, Riyadh, Saudi Arabia; 2Liver and Small Bowel Transplant, KFSHRC, Riaydh, Saudi Arabia.

    This is an open label, prospective, interventional cohort study conducted at a tertiary referral center. The primary end point is SVR12 in patients treated with…
  • 2016 American Transplant Congress

    Share35 Liver Allocation Is Associated with Increased Early Graft Failure Rate.

    T. Wong,1 N. Koizumi,2 J. Ortiz.3

    1Maricopa Medical Center, Phoenix, AZ; 2George Mason University, Arlington, VA; 3University of Toledo, Toledo, OH.

    Background: The implementation of Share35 liver allocation policy in June 2013 facilitated the increase in number of transplanted livers with less organ discards. Early analysis…
  • 2016 American Transplant Congress

    Impact of Early Allograft Dysfunction (EAD) and Its Components on Patient Survival Following Liver Transplantation (LT): Long-Term Outcomes Up to 10 Years.

    B. Ekser, R. Mangus, J. Fridell, C. Kubal, J. Davis, J. Salisbury, T. Salisbury, S. Nagaraju, P. Mihaylov, A. Tector.

    Transplant Division, Department of Surgery, Indiana University, Indianapolis, IN.

    Background: It has been shown that EAD in LT is a useful tool to predict intermediate (5-year) mortality. The purpose of this study is to…
  • 2016 American Transplant Congress

    Mothers Are Often Sensitized and Sensitive: Antibody Mediated Rejection in Child to Mother Living Donor Liver Transplantation.

    B. Movahedi,1 N. Yu,2 P. Martins,1 A. Ahearn,1 J. Stoff,1 A. Bozorgzadeh.1

    1Division of Organ Transplantation, UMass Memorial Medical Center, Worcester, MA; 2Clinical Pathology, Histocompatibility Laboratory, UMass Memorial Medical Center, Worcester, MA.

    Background: Partial graft is especially more vulnerable to deleterious effects of donor specific HLA antibodies (DSA). Living liver donors and recipients are often family members.…
  • 2016 American Transplant Congress

    Comparative Analysis of Patients with Mixed Hepatocellular-Cholangiocarcinoma (HCC-CCA) Undergoing Liver Transplantation: A Single Center Matched Cohort Analysis.

    K. Lunsford, M. Harlander-Locke, J. Gornbein, A. Zarrinpar, F. Kaldas, H. Yersiz, D. Farmer, R. Busuttil, V. Agopian.

    Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA.

    Liver transplant (LT) is the gold standard for hepatocellular carcinoma (HCC) but is contraindicated in known HCC-CCA due to poor prognosis. We compared posttransplant oncologic…
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