Articles tagged "Liver transplantation"

2016 American Transplant Congress
The Heterogenous Genomic Landscape of Unresectable Hepatoblastoma Requiring Liver Transplantation: Prognostic Implications.
M. Ningappa, B. Higgs, S. Ranganathan, C. Ashokkumar, R. Sindhi.
Surgery, Children's Hospital of Pittsburgh of UPMC and University of Pittsburgh, Pittsburgh, PA.
Background: Hepatoblastoma, the most common pediatric liver malignancy, is cured by chemotherapy and surgical resection. Locally invasive/multifocal tumors require liver transplantation (LTx). A unique tumor…
2016 American Transplant Congress
Outcomes of Ribavirin Free Treatment of Recurrent Genotype 1 , Hepatitis C Infection Post Liver Transplant.
D. Jones,¹ S. Baggett,¹ M. Shoreibah,² O. Massoud.²
¹Department of Pharmacy, UAB Hospital, Birmingham, AL; ²Department of Gastroenterology, UAB Hospital, Birmingham, AL.
Background. With the development of direct-acting antivirals, the treatment of Hepatitis C Virus (HCV) has become a rapidly changing area of medical practice. Data on…
2016 American Transplant Congress
Live Donor Liver Transplantation for NASH: The Toronto Experience.
A. Barbas, N. Goldaracena, M. Dib, M. Marquez, G. Sapisochin, D. Al-Adra, I. McGilvray, M. Cattral, P. Greig, D. Grant.
General Surgery, Multi-Organ Transplant, University of Toronto, Toronto, ON, Canada.
Background:Non-alcoholic steatohepatitis (NASH) is an increasingly common indication for liver transplantation in North America. In the context of organ scarcity and significant waitlist mortality, our…
2016 American Transplant Congress
Hepatocellular Carcinoma Decreases Chance of Successful HCV Therapy in the Current Era.
S. Prenner, L. VanWagner, L. Kulik.
Gastroenterology and Hepatology, Northwestern University, Chicago, IL.
Background: The efficacy of direct acting antiviral agents (DAA) for hepatitis C (HCV) in patients with hepatocellular carcinoma (HCC) is limited. We hypothesized that virology…
2016 American Transplant Congress
Experience Using a Discharge Calculator for Discharge Planning Post Liver Transplantation (OLT).
K. Kerepesi, A. Waby, K. Eid, J. Plescia, K. Zinn, K. Vass, B. Eghtesad, C. Miller, D. Kelly.
Cleveland Clinic, Cleveland, OH.
We previously developed and validated a nomogram to predict discharge disposition post OLT. The current study analyzes our experience using the discharge calculator.Patients &Methods:We retrospectively…
2016 American Transplant Congress
Subnormothermic Machine Perfusion (SNMP) of Liver Allografts with a Novel Hemoglobin-Based Oxygen Carrier (HBOC) Increases β-Oxidation of Fatty Acids and Decreases Lipid Peroxidation (LP).
B. Banan, R. Lopez, C. Hughes, G. Michalopoulos, P. Fontes.
University of Pittsburgh, Pittsburgh.
Introduction: There is limited information about the lipid metabolic profile during liver allograft preservation. LP remains a major component of ischemia-reperfusion injuries (IRIs). The aim…
2016 American Transplant Congress
Opioid-Sparing Pain Management Improves Outcomes and Safety in Living Liver Donors.
D. Ladner,¹ E. Pomfret,² M. Simpson,² J. Guarrera,³ R. Fisher,⁴ A. Skaro,¹ T. Baker,¹ T. Curtis,¹ A. Daud,¹ B. Platt,¹ R. Kang,¹ N. Salehitezangi,¹ J. Holl,¹ M. Abecassis,¹ D. Woods.¹
¹Northwestern University, Chicago, IL; ²Lahey Clinic, Burlington, MA; ³Columbia University, New York, NY; ⁴Virginia Commonwealth Univeristy, Richmond, VA.
BACKGROUND: As part of the ancillary four center study, to the Adult-to-Adult Living Donor Liver Transplant Cohort Study (A2ALL), over 75% of living liver donors…
2016 American Transplant Congress
A Multi-Modular Approach for Training in Liver Procurement Accelerates Proficiency Gain.
I. Al Hasan,^1,2 H. Sharma,^1,2 M. Tun-Abraham,¹ D. Quan.^1,2
¹Department of Surgery, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON, Canada; ²Multi-Organ Transplant Program, London Health Sciences Centre, London, ON, Canada.
BACKGROUND: Modular training has been established as an educational tool in colorectal and urology surgery for the last 5 years. This modular operative approach is…
2016 American Transplant Congress
Liver Transplantation in Patients Actively Drinking Less Than 6 Months Before Transplant Presenting with Acute Decompensation: A Single-Center Experience.
H. Monsour, D. Victor, M. Boktour, J. Galati, J. Ontiveros, L. Theriot, R. McFadden, C. Mobley, A. Saharia, S. Gordon-Burroughs, A. Gaber, R. Ghobrial.
Sherrie and Alan Conover Center for Liver Disease and Transplantation, Houston Methodist Hospital, Houston, TX.
Background: Alcohol is amongst the leading causes of liver disease worldwide. Most centers have a 6-month abstinence requirement before transplantation candidacy. Mortality rates for acute…
2016 American Transplant Congress
Recombinant TSGL-Ig Protects Liver Endothelial Cells Against Prolonged Cold Preservation Injury in Mouse Liver Transplantation.
C. Zhang,^1,2 H. Ji,¹ Y. Liu,^1,2 Y. Zhang,^1,2 X.-D. Shen,¹ F. Gao,¹ R. Busuttil, G. Shaw, J. Kupiec-Weglinski.
¹Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at University of California-Los Angeles, Los Angeles, CA; ²Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Background: Liver endothelial cells (LEC) suffer from ROS-mediated stress in the pathogenesis of liver ischemia-reperfusion injury (IRI). We used a novel recombinant form of soluble…