Articles tagged "Liver transplantation"

2022 American Transplant Congress
Locoregional Therapy for Hepatocellular Carcinoma Decreases Liver Transplant Waitlist Dropout and Mortality
S. Weeks, T. Ishaque, A. Massie, D. Segev, E. King
Johns Hopkins, Baltimore, MD
*Purpose: Liver transplant candidates with hepatocellular carcinoma (HCC) risk tumor progression that may disqualify them from transplant eligibility while awaiting HCC exception points on the…
2022 American Transplant Congress
Immune Checkpoints, Immune Cells, and MHC Expression in the Tumor Microenvironment of Resected Hepatocellular Carcinomas
A. Baquerizo¹, V. Vavinskaya², S. Bagsic¹, A. Rojas³, A. Mhoyan⁴, C. Frenette¹, L. Sher⁵, M. Romero³, J. Fisher¹, C. Marsch¹, R. Schaffer¹
¹Scripps, La Jolla, CA, ²UCSD, San Diego, CA, ³University, Seville, Spain, ⁴Kaiser, San Diego, CA, ⁵USC, Los Angeles, CA
*Purpose: Advances in tumor biology has shown the important role of the tumor microenvironment (TME) in tumor growth and metastasis. A better understanding of the…
2022 American Transplant Congress
Sars-cov2 Antibody Kinetics and Durability Three and Six Months After Two-Doses of MRNA Vaccination in Liver Transplant Recipients
A. Chang¹, A. T. Strauss¹, T. P. Chiang¹, A. Jennifer¹, H. Nicole¹, L. Zeiser¹, B. Boyarsky¹, R. Avery¹, A. Tobian¹, M. Levan¹, D. Warren¹, A. Massie¹, J. Garonzik-Wang², D. Segev¹, W. Werbel¹
¹Johns Hopkins University School of Medicine, Baltimore, MD, ²University of Wisconsin School of Medicine, Madison, WI
*Purpose: nti-spike antibody response to SARS-CoV-2 vaccination is diminished in LT recipients compared to the general population so understanding durability for those that do respond…
2022 American Transplant Congress
Real-Time Application of Deep Learning in Diagnosis of Graft Fibrosis After Liver Transplantation Using Longitudinal Data
A. Azhie¹, D. Sharma², P. Sheth¹, W. Xu³, M. Bhat¹
¹Ajmera Transplant Program, University Health Network, Toronto, ON, Canada, ²Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada, ³Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
*Purpose: Graft fibrosis develops insidiously in liver transplant recipients and is associated with worse survival. Early detection of fibrosis is essential to avoid further progression…
2022 American Transplant Congress
Vitamin D Deficiency in Liver Transplant Recipients
V. Subramanian¹, T. Lippert², J. Buggs¹, N. Kemmer¹, K. Dhanireddy¹
¹Transplant Institute, Tampa General Hospital, Tampa, FL, ²University of South Florida, Tampa, FL
*Purpose: Patients with chronic liver disease are at risk of nutritional deficiency. The goal of this study was to determine the prevalence of vitamin D…
2022 American Transplant Congress
Utilizing Microsurgeon Expertise in the Salvage of Hepatic Artery Dissection
R. Sitta¹, N. Ascher², J. Roberts², M. Piper³
¹General Surgery, UCSF, San Francisco, CA, ²Abdominal Transplant Surgery, UCSF, San Francisco, CA, ³Plastic and Reconstructive Surgery, UCSF, San Francisco, CA
*Purpose: Living donor hepatic artery intimal dissection is a rare but devastating complication often resulting in inability to utilize the graft. We detail the salvage…
2022 American Transplant Congress
Internal Validation of a Pre-Transplant Biomarker Panel to Predict Post-Transplant Mortality: The Liver Immune Frailty Index
G. G. Panayotova¹, D. T. Nguyen², E. A. Graviss², L. J. Minze², S. Simonishvili¹, Y. Qin¹, T. Ayorinde¹, G. Prakash¹, F. Paterno¹, L. Brown¹, A. Amin¹, X. C. Li², R. M. Ghobrial², J. V. Guarrera¹, K. E. Lunsford¹
¹Rutgers New Jersey Medical School, Newark, NJ, ²Houston Methodist Hospital, Houston, TX
*Purpose: Infection and sepsis are the greatest contributors to early post-liver transplant (LT) mortality. These often result from ongoing immune dysfunction, or “Immune Frailty”. We…
2022 American Transplant Congress
Evolution of Pretransplant Cardiac Risk Factor Burden and Major Adverse Cardiovascular Events in Liver Transplant Recipients Over Time
C. Harrington, P. Levy, E. Cabrera, J. Gao, D. Gregory, C. Padilla, G. Crespo, L. VanWagner
Northwestern Medicine, Chicago, IL
*Purpose: The aim of this study is to evaluate the evolution of MACE and pre-LT cardiac risk factors in LTRs over time.*Methods: This is a…
2022 American Transplant Congress
Pre-Transplant Self-Report of Length of Sobriety is Not Significantly Related to Early Return to Alcohol Use Post Transplant
J. Esswein¹, A. Powell¹, H. Bruschwein², S. Weinland¹
¹Psychiatry, VCU School of Medicine, Richmond, VA, ²The University of Virginia, Charlottesville, VA
*Purpose: Many transplant centers in the United States require six months of abstinence from alcohol prior to liver transplant. Recently, there has been an increased…
2022 American Transplant Congress
Utility of Donor Derived Cell-Free DNA in Liver Transplantation
A. Zarrinpar, D. Lewis, C. Warren, S. Duarte
Surgery, University of Florida, Gainesville, FL
*Purpose: As a non-invasive measure of allograft injury, quantifying the fraction of donor-derived cell-free DNA (dd-cfDNA) has proven to be useful technique in kidney transplantation.…