Articles tagged "Liver transplantation"

2022 American Transplant Congress
Temporal Changes in the Peripheral Immune Profile of Acute Rejection Highlight New Mechanisms of Alloimmunity and Potential Non-Invasive Biomarkers of Rejection in Pediatric Liver Transplantation
D. N. Sarode¹, B. Rocque¹, A. Barbetta¹, P. Singh¹, C. Goldbeck¹, C. Weaver², O. Akbari¹, R. Kohli², J. Emamaullee¹
¹University of Southern California Keck School of Medicine, Los Angeles, CA, ²Children's Hospital Los Angeles, Los Angeles, CA
*Purpose: Acute rejection (AR) is common in pediatric liver transplantation (LT) and can impact late graft loss. Immune subpopulations mediating AR in LT have not…
2022 American Transplant Congress
Revisiting Late Graft Loss or Death in Pediatric Liver Transplantation Through Analysis of the SPLIT Database
J. E. Squires¹, J. Bilhartz², K. Soltys¹, E. Hafberg³, G. V. Mazariegos¹, N. Gupta⁴, R. Anand⁵, S. G. Anderson⁵, T. Miloh⁶
¹UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, ²C. S. Mott Children's Hospital, Ann Arbor, MI, ³Vanderbilt University School of Medicine, Nashville, TN, ⁴Children's Healthcare of Atlanta and Emory University School of Medicine, Attlanta, GA, ⁵The Emmes Company, Rockville, MD, ⁶University of Miami, Miami, FL
*Purpose: With advances in surgical techniques, medical management, and more equitable allocation systems, children who receive a liver transplant today can expect remarkable outcomes early…
2022 American Transplant Congress
Reality Capture Using Light Detection and Ranging 3D Photography of Liver Grafts for Volumetric Assessment: A Proof-of-Concept Preliminary Study
K. E. Karakasi¹, G. Katsanos², I. Karolos³, V. Tsioukas³, G. Tsoulfas⁴
¹University Transplantation Surgical Clinic, Heppocrateion General Hospital, Thessaloniki, Greece, ²Transplantation, Aristitle University of Thessaloniki, Thessaloniki, Greece, ³School of Runal and Surveying Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece, ⁴University Transplantation Surgical Clinic, Hippocrateion’ General Hospital of Thessaloniki, Thessaloniki, Greece
*Purpose: Reality capture uses various technical means to capture a digital 3D model representation of a subject from the real world. Whole liver graft volume…
2022 American Transplant Congress
Proteomic Profiling of Bile from Human Livers Undergoing Viability Assessment via Normothermic Machine Perfusion Prior to Transplantation
A. M. Thorne¹, J. C. Wolters², F. Kuipers¹, R. J. Porte¹, V. E. de Meijer¹
¹University Medical Center Groningen, Groningen, Netherlands, ²University of Groningen, Groningen, Netherlands
*Purpose: Normothermic machine perfusion (NMP) has gained increasing traction as a method to assess the viability of high-risk donor livers. To avoid post-transplant biliary complications,…
2022 American Transplant Congress
The Financial Burden Of Transplant – A Commercial Claims Analysis
G. Katz-Greenberg¹, O. Osazuwa-Peters¹, J. Gonzalez¹, S. Sanoff¹, O. Oloruntoba¹, N. Chan¹, E. J. Gordon², C. Scales¹, A. Brookhart¹, L. McElroy¹
¹Duke University, Durham, NC, ²Surgery, Northwestern University Feinberg School of Medicine, OAK PARK, IL
*Purpose: Despite access to health insurance, financial concerns are among the most prevalent patient-reported barriers to kidney and liver transplantation (KT and LT, respectively). We…
2022 American Transplant Congress
Living Donor Liver Transplantation: A Better Option for Patients 70 Years or Older
A. Ganoza, A. Duarte-Rojo, V. Gunabushanam, M. Molinari, S. Ganesh, D. Reddy, A. M. Thompson, A. Tevar, C. Hughes, A. Humar
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: The burden of liver diseases in patients of advanced age has risen. Irrespective of its possible causes, older recipients have a higher waitlist mortality…
2022 American Transplant Congress
DCD Liver Grafts Can Safely be Used for Recipients with Grade 1-2 Portal Vein Thrombosis
L. A. Mercado¹, H. K. Bhangu¹, K. R. Musto², K. D. Watt³, B. Taner⁴, C. B. Rosen⁵, T. Taner⁵, L. Yang¹, D. M. Harnois¹, J. D. LeGout⁶, K. P. Croome⁴
¹Liver Transplant, Mayo Clinic, Jacksonville, FL, ²Transplant, Mayo Clinic, Jacksonville, FL, ³Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, ⁴Transplant Surgery, Mayo Clinic, Jacksonville, FL, ⁵Transplant Surgery, Mayo Clinic, Rochester, MN, ⁶Radiology, Mayo Clinic, Jacksonville, FL
*Purpose: Limited data is available in the literature regarding patients with portal vein thrombosis (PVT) receiving a liver transplant (LT) from a donation after circulatory…
2022 American Transplant Congress
Unique Treatment of Duodenal Perforation in Middle Aged Female Patient with Liver Transplant
H. Elshebiny¹, J. Syed-Mohammed²
¹Wayne State University School of Medicine, Detroit, MI, ²Henry Ford Health System, Detroit, MI
*Purpose: We describe a unique method of treatment of duodenal perforation due to biliary stent using an over the scope clip-OTSC.*Methods: A 68 year old…
2022 American Transplant Congress
National Attitudes Towards Early Liver Transplantation for Alcoholic Liver Disease
J. Mitchell¹, K. Nijhar¹, K. Herrick-Reynolds², H. Sung¹, P. Chen¹, D. L. Segev¹, E. King¹, A. Cameron¹
¹Department Of Surgery, Johns Hopkins University, Baltimore, MD, ²Department Of Surgery, Walter Reed National Military Medical Center, Bethesda, MD
*Purpose: Pre-transplant abstinence requirements, notably the 6-month sobriety guideline, limit access to liver transplant for patients with severe alcoholic hepatitis (SAH). This study examines the…
2022 American Transplant Congress
Phase I/ii Car-Treg Cell Therapy Clinical Trial To Induce Long-term Tolerance In Liver Transplant Patients
A. Sanchez-Fueyo¹, A. Taylor¹, D. Collin², C. Nathalie², S. Chris², M. Martinez-Llordella², N. Belmonte², I. McGill², D. Hartl²
¹King's College London, London, United Kingdom, ²Quell Therapeutics Ltd, London, United Kingdom
*Purpose: Life-long pharmacological immunosuppression (IS) is considered essential to prevent rejection following liver transplantation (LT), but is associated with significant side effects such as infections,…