Articles tagged "Liver transplantation"

2022 American Transplant Congress
Liver Transplant Outcomes with Persistent Post Transplant Alcohol Consumption
B. Evans¹, D. Patino², R. Sauls³, R. Shargo³, S. Mohammed³, M. Gosselin⁴, K. Robichaux³, A. Kumar⁵, J. Buggs¹
¹Transplant Surgery, Tampa General Hospital, Tampa, FL, ²Michigan State University College of Human Medicine, Lansing, MI, ³University of South Florida, Tampa, FL, ⁴University of Tampa, Tampa, FL, ⁵Morsani College of Medicine, University of South Florida, Tampa, FL
*Purpose: Although transplant centers educate patients on outcome risks from alcohol relapse, half of the alcoholic liver disease patients are thought to consume alcohol after…
2022 American Transplant Congress
Transplant Combined with Neoadjuvant Therapy Improves Survival for Patients with Liver-Limited, Locally Advanced Intrahepatic Cholangiocarcinoma: A SEER Database Analysis
G. G. Panayotova¹, M. Javle², S. Pentakota¹, F. Paterno¹, A. Amin¹, L. Brown¹, S. Simonishvili¹, Y. Qin¹, T. Ayorinde¹, G. Prakash¹, C. Conrad³, J. V. Guarrera¹, K. E. Lunsford¹
¹Rutgers New Jersey Medical School, Newark, NJ, ²University of Texas, MD Anderson Cancer Center, Houston, TX, ³St. Elizabeth's Medical Center, Boston, MA
*Purpose: Preliminary single-center data suggest multimodal therapy may improve outcomes for patients with intrahepatic cholangiocarcinoma (iCCA) undergoing liver transplant (LT), particularly in the setting of…
2022 American Transplant Congress
Impact of a Pharmacy-Led Post-Transplant Diabetes Mellitus Clinic in Solid Organ Transplant Recipients
H. Sweiss¹, R. Hall¹, M. Flores², S. Bhayana¹, R. Patel¹, C. Long²
¹University Health - University Hospital, San Antonio, TX, ²College of Pharmacy, University of Incarnate Word, San Antonio, TX
*Purpose: To evaluate the impact of a pharmacy-led post-transplant diabetes mellitus (DM) clinic.*Methods: This retrospective chart review from 08/01/20 to 6/30/21 evaluated adult kidney transplant…
2022 American Transplant Congress
Exploration of the Optimal pH in Hypothermic Machine Perfusion for Rat Liver Grafts Retrieved from Circulatory Death
S. Sakamoto¹, M. Fukai¹, K. Shibata¹, H. Bochimoto², N. Mohd Zin², N. Kawamura¹, T. Ishikawa¹, M. Fujiyoshi¹, T. Shimamura³, A. Taketomi¹
¹Department of Gastroenterological Surgery 1, Hokkaido University Graduate School, Sapporo, Japan, ²Department of Cell Physiology, The Jikei University School of Medicine, Tokyo, Japan, ³Division of Organ Transplantation, Hokkaido University Hospital, Sapporo, Japan
*Purpose: Although some investigators have reported favorable results of hypothermic machine perfusion (HMP) in liver transplantation, the efficacy to the hepatic graft retrieved from circulatory…
2022 American Transplant Congress
Higher Hepatocellular Carcinoma Tumor Burden Score is Associated with Grater Liver Transplant Survival Benefit
H. Liu¹, W. Zhang², M. Di³, H. Lee⁴, R. Cruz¹, X. Wang², C. Kaltenmeier¹, A. Thompson¹, D. Reddy¹, E. Ashwat¹, M. D'Alesio¹, S. Lebowitz¹, S. Tohme¹, D. Geller¹, A. Tevar¹, C. Hughes¹, A. Humar¹, J. Behari⁵, R. Bataller⁵, S. Hariharan⁵, M. Molinari¹
¹Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, ²Mathematics and Statistics, University of Arkansas at Little Rock, Little Rock, AR, ³Medicine, Medical Oncology, Yale University, New Haven, CT, ⁴Biostatistics, Massachusetts General Hospital, Boston, MA, ⁵Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Liver transplantation(LT) is the best treatment option for early-stage hepatocellular carcinoma(HCC) and cirrhosis. However, patients with various tumor burdens receive identical listing priority, despite…
2022 American Transplant Congress
Does Machine Perfusion of Heart for Donation After Cardiac Death (DCD) Transplantation Affect Other Organ Outcomes?
R. Misawa¹, K. Okumura², H. Sogawa¹, G. Veillette¹, A. Dhand³, R. Bodin⁴, D. C. Wolf⁴, B. Partiula⁴, D. John¹, T. Diflo⁵, S. Nishida¹
¹Department of Surgery, Transplant, Westchester Medical Center/New York Medical College, Valhalla, NY, ²Surgery, Westchester Medical Center/New York Medical College, Valhalla, NY, ³Department of Medicine, Westchester Medical Center/New York Medical College, Valhalla, NY, ⁴Medicine, Westchester Medical Center/New York Medical College, Valhalla, NY, ⁵Westchester Medical Center/New York Medical College, Valhalla, NY
*Purpose: Machine perfusion of heart for donation after cardiac death (DCD) transplants is being increasingly utilized. Initial protocol of the heart machine perfusion for the…
2022 American Transplant Congress
Role for Club Cell Secretory Protein in Inducing Exosomes and Activation of Immune Responses in Lung Transplanted Recipients for Cystic Fibrosis
R. Ravichandran¹, V. Kaza², R. Bremner¹, M. Smith¹, T. Mohanakumar¹
¹St. Joseph’s Hospital and Medical Center, Phoenix, AZ, ²University of Texas Southwestern, Dallas, TX
*Purpose: Our lab has demonstrated that lower club cell secretory protein leads to immune responses to donor HLA and lung self-antigens (Collagen V, Kα1 Tubulin),…
2022 American Transplant Congress
End-to-Side Splenic to Hepatic Artery Reconstruction in Liver Transplant: A Case Series
N. Baker, L. Aviles-Ovalle, T. Baker, J. Campsen, R. Kim, G. Rofaiel
Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT
*Purpose: Optimal hepatic artery (HA) blood flow post-liver transplantation (LT) is necessary for long-term allograft success. HA thrombosis (HAT) contributes to significant morbidity and mortality…
2022 American Transplant Congress
Adoptive Transfer OfMesenchymal Stem Cells Activates Hedgehog/SMO/Gli1 Signaling And Inhibits STING-mediated Innate Immune Response In Liver Transplant Inflammatory Injury
D. Xu¹, X. Qu¹, Y. Tian¹, M. Sheng¹, Y. Lin¹, Y. Zhan¹, F. M. Kaldas¹, R. W. Busuttil¹, D. G. Farmer¹, J. W. Kupiec-Weglinski¹, Q. Xia², B. Ke¹
¹Surgery, Dumont - UCLA Transplant Ctr, Los Angeles, CA, ²Liver Surgery, Shanghai Jiaotong University School of Medicine, Shanghai, China
*Purpose: The stimulator of interferon genes (STING) pathway has been recognized as a crucial signaling cascade of the innate immune system. Activation of the Hedgehog…
2022 American Transplant Congress
Measurement of Physical Activity and Frailty in the Early Post-Operative Period After Liver Transplant Surgery: Single-Center Pilot Study Using Fitbit Watch
T. Shamaa, L. Allenspach, O. Shamaa, S. Shimada, C. Crombez, O. Hage-Hassan, T. Kitajima, S. Yeddula, I. Bajjoka, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai
Henry Ford Transplant Institute, Detroit, MI
*Purpose: Robust physical activity after liver transplant (LT) is an important determinant of long-term health. Patient and providers assessments of perioperative physical activity do not…