2017 American Transplant Congress
Rapamycin Maintenance Therapy in Pediatric Liver Transplant Recipients Associated with Trend Toward Decreasing Th2 Cytokine Levels Compared to Tacrolimus Therapy.
1Children's Mercy Hospital, Kansas City, MO; 2University of Kansas Medical Center, Kansas City, KS
Background: Maintenance immunosuppression after liver transplantation with tacrolimus (TAC) may have progressive fibrosis on serial allograft biopsies. mTOR inhibitors such as rapamycin (RAPA) may abrogate…2017 American Transplant Congress
Disease Progression on Neoadjuvant Chemotherapy Is a Strong Predictor of Recurrence for Pediatric Hepatoblastoma.
1Surgery, Baylor College of Medicine, Houston; 2Surgery, Texas Children's Hospital, Houston
Purpose. In addition to peri-operative chemotherapy, proper triage between orthotopic liver transplantation (OLT) and partial hepatectomy (PH) is critical to limiting disease recurrence in pediatric…2017 American Transplant Congress
Tolerant Pediatric Liver Transplant (LT) Recipients (TOL) from WISP-R (NCT00320606) Split into Two Phenotypically Distinct Groups by PD1 Expression on CD4+ T Cells at Baseline, Prior to Immunosuppression Withdrawal (ISW).
Background: Combinations of cell surface markers such as PD1, CD57, and/or KLRG1 identify T cells that may fail to respond to cognate antigen challenge –…2017 American Transplant Congress
HOPE Act – The First Year.
United Network for Organ Sharing, Richmond, VA
Background: The HIV Organ Policy Equity (HOPE) Act, enacted on 11/21/13, allows for research on transplants of kidneys (KI) or livers (LI) from HIV+ donors…2017 American Transplant Congress
The Effect of the Procurement Surgeon on Transplanted Abdominal Organ Outcomes: An OPTN/SRTR Analysis to Evaluate Regional Organ Procurement Collaboration.
OBJECTIVE: A number of single center studies have demonstrated utility of regional organ procurement collaboration to reduce travel redundancy by procuring surgical teams with no…2017 American Transplant Congress
Different Prognostic Factors for Early and Late Recurrence After Adult Living Donor Liver Transplantation for Hepatocellular Carcinoma.
Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea
Recurrence after liver transplantation (LT) for hepatocellular carcinoma (HCC) remains unsatisfactory. However, some patients with HCC recurrence after LT show good long-term survival results. The…2017 American Transplant Congress
Identification of Novel Diagnostic Biomarkers in Liver Transplantation Tolerance.
1Cleveland Clinic, Cleveland; 2University of Chicago, Chicago
Current success in liver transplantation (LTX) relies on life-time administration of non-specific immunosuppressive drugs, leaving patients prone to infection and cancer. Previous reports indicated about…2017 American Transplant Congress
Myeloid HO-1 Regulates M2 Macrophage Activation in Liver Ischemia-Reperfusion Injury (IRI).
Background/Aim: Although anti-inflammatory macrophage differentiation (M2) from pro-inflammatory (M1) phenotype is critical for heme oxygenase-1 (HO-1) cytoprotection, the role of cell type-specific HO-1 induction remains…2017 American Transplant Congress
A Novel Method for Detecting and Monitoring Chimerism in Patients with Graft versus Host Disease After Liver Transplantation.
Background Graft versus host disease (GVHD) after orthotopic liver transplantation (OLT) is a rare but lethal complication. Early diagnosis and treatment is critical for a…2017 American Transplant Congress
Liver Transplantation for Adolescents with Biliary Atresia in the PELD/MELD Era: An Analysis of the UNOS Database.
While poor bile drainage after a Kasai hepatoportoenterostomy (KPE) is the primary driver for liver transplantation (LT) for Biliary Atresia (BA) in infancy, the data…
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