ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2018 American Transplant Congress

    The Net State of Immunosuppression in Septuagenarian Liver Transplant Recipients: Balancing Rejection and Infection Risks

    J. Casale,1 J. Clark,1 B. Ravichandran,1 J. LaMattina.2

    1Pharmacy, University of Maryland Medical Center, Baltimore; 2University of Maryland School of Medicine, Baltimore.

    Purpose: Careful patient selection and perioperative management have allowed for successful liver transplantation in elderly patients. Elderly patients may be more susceptible to the infectious…
  • 2018 American Transplant Congress

    Poverty, End Stage Liver Disease, and Transplantation in Georgia

    R. Lynch,1 K. Ross,1 J. Magliocca,1 D. Goldberg,2 R. Patzer.1

    1Surgery, Emory University, Atlanta, GA; 2Medicine, University of Pennsylvania, Philadelphia, GA.

    Background: Though discussions of equity in liver transplantation remain focused primarily on relative availability of allografts as a measure of access, differences in disease burden…
  • 2018 American Transplant Congress

    Evaluation of Risk Factors for Vancomycin Resistant Enterococcus (VRE) Infection in Adult Liver Transplant Recipients

    E. Aldag, R. Pedersen, V. Gunabushanam, A. Sahajpal, L. Fehrenbacher, D. Kramer.

    Aurora St Luke's Medical Center, Milwaukee, WI.

    Background: VRE infections are associated with higher morbidity and mortality among patients undergoing liver transplantation.Objective: The primary outcome is to examine the association between Endoscopic…
  • 2018 American Transplant Congress

    Viability Outcomes for Donor Livers Discarded Due to Steatosis Following Extra-Corporeal Machine Perfusion of the Liver

    Y. Boteon,1,2 R. Laing,1,2 D. Neil,2 A. Schlegel,2 J. Attard,1,2 G. Reynold,1 P. Muiesan,2 D. Mirza,2 S. Afford,1 H. Mergental.2

    1National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; 2Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.

    Background: Steatosis is the main reason for discarding donor livers worldwide. Ex-vivo machine perfusion offers superior preservation for marginal organs and permits viability testing during…
  • 2018 American Transplant Congress

    Long-Term Outcomes after Living Liver Donation: Analysis of National Data Base

    S. Hong, N-.J. Yi, K. Yoon, J-.H. Cho, J-.M. Lee, H. Kim, K. Lee, K. Suh.

    Surgery, Seoul National University College of Medicine, Seoul, Korea.

    Background: Every year, more than 800 healthy people undergo hepatic resection for living liver donation in Korea. Although 27 years has passed since the first…
  • 2018 American Transplant Congress

    A Comparison of the Discard Rate in Hepatitis C Deceased Liver Donors between Two Eras, 2008-2013 and 2014-2017. A Single Organ Procurement Organization Experience

    M. Nazzal,1 G. Marklin,2 O. Okoye,1 Y. Kim,1 R. Ouseph.1

    1Abdominal Transplant, Saint Louis University, Saint Louis, MO; 2Mid America Transplant, Saint Louis, MO.

    With the introduction of new hepatitis C medications in 2014 , there is a growing concern for an increase in the discard rate of hepatitis…
  • 2018 American Transplant Congress

    Intestinal Microbiome Diversity is Associated with Liver Disease Etiology and Predicts Post-Liver Transplant Mortality

    E. Verna, M. Annavajhala, M. Nenad, R. Brown, S. Sullivan, G. Korakani, M. Gidins, S. Khan, A. Gomez-Simmonds, A-.C. Uhlemann.

    Medicine, Columbia University, New York, NY.

    Background: Dysbiosis of the intestinal microbiome is common among patients with decompensated liver disease and has been associated with disease progression as well as life-threatening…
  • 2018 American Transplant Congress

    Resuscitation and Viability Testing of Initially Declined Livers Using Sequential Hypo- and Normothermic Machine Perfusion with an Acellular Fluid

    Y. de Vries,1,2 A. Matton,1,2 S. Karangwa,1,2 M. Nijsten,3 R. de Kleine,2 A. van den Berg,4 V. de Meijer,2 P. Meyer,5 M. de Boer,2 R. Porte.2

    1Surgical Research Laboratory, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; 2Section of HPB Surgery and Liver Transplantation, University Medical Center Groningen, Groningen, Netherlands; 3Department of Critical Care, University Medical Center Groningen, Groningen, Netherlands; 4Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, Netherlands; 5Department of Anesthesiology, University Medical Center Groningen, Groningen, Netherlands.

    While end-ischemic dual hypothermic oxygenated machine perfusion (DHOPE) resuscitates mitochondria and reduces ischemia-reperfusion injury, normothermic machine perfusion (NMP) allows for ex-situ functional testing of donor…
  • 2018 American Transplant Congress

    Post Reperfusion Portal Flow Rate Impacts Liver Allograft and Patient Survival in Patients with Pre Transplant Portal Vein Thrombosis

    M. Rizzari, M. Safwan, M. Sobolic, S. Nagai, R. Schilke, K. Collins, A. Yoshida, M. Abouljoud.

    Henry Ford Transplant Institute, Henry Ford Health System, Detroit, MI.

    Background: Pre-transplant (pretx) portal vein thrombosis (PVT) not only makes the technical aspect of liver transplantation more challenging, it also is known to affect outcomes.…
  • 2018 American Transplant Congress

    Liver Transplant Survival Index for Recipients with High MELD Score: A Model for Post-Transplant Survival in Severely Ill Patients

    J. Steggerda,1 M. Bloom,1 C. Bresee,2 D. Malinoski,3 A. Klein,1 K. Kim.1

    1Surgery, Cedars-Sinai Medical Center, Los Angeles, CA; 2Biostatistics, Cedars-Sinai Medical Center, Los Angeles, CA; 3Surgery, Oregon Health Science University, Portland, OR.

    Background: SHARE-35 prioritizes patients with MELD scores ≥35 for regional sharing of liver allografts. Because this policy incentivizes transplantation of sicker patients, this study examines…
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