Articles tagged "Liver transplantation"

2018 American Transplant Congress
Factors Impacting Return to Employment after Liver Transplantation
M. Hassan, M. Abouljoud, N. Sadik, A. Mazur, A. Elbanna, A. Yoshida, M. Jesse.
Henry Ford Health System, Detroit.
Liver transplantation (LT) prolongs the lives of patients with end-stage liver disease (ESLD). Post-LT, 22-55% of patients return to some form of active employment. Age…
2018 American Transplant Congress
Biliary pH, Bicarbonate and Glucose Are Suitable Biomarkers of Bile Duct Viability during Normothermic Machine Perfusion of Human Donor Livers
A. Matton,^1,2 Y. de Vries,^1,2 L. Burlage,^1,2 R. van Rijn,^1,2 A. Gouw,³ V. de Meijer,¹ T. Lisman,² R. Porte.¹
¹Department of Surgery, Section Hepatopancreatobiliary Surgery & Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; ²Surgical Research Laboratory, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; ³Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Background: Normothermic machine perfusion (NMP) is rapidly making its way into the clinic and can be used for viability assessment of human donor livers prior…
2018 American Transplant Congress
Predicting Acute Kidney Injury after Orthotopic Liver Transplantation Using a Recurrent Neural Network
A. Bishara, R. Kothari, M. Bokoch, C. Niemann, D. Adelmann.
UCSF, San Francisco.
In patients undergoing orthotopic liver transplantation (OLT), the incidence of acute kidney injury (AKI) is up to 60%. Prediction of the individual patient's risk of…
2018 American Transplant Congress
Small-for-Size Grafts Increase Recurrence of Hepatocellular Carcinoma in Liver Transplantation beyond Milan Criteria
E. Lee, S. Kim, J. Shim, J. Park, B. Na, S-.J. Park.
Center for Liver Cancer, National Cancer Center, Goyang, Korea.
BACKGROUND: Living donor liver transplantation (LDLT) has been reported to have high rates of hepatocellular carcinoma (HCC) recurrence compared to deceased donor liver transplant (DDLT).…
2018 American Transplant Congress
Technical Aspects of Orthotopic Liver Transplantation – A Survey-Based Study within the Eurotransplant, Swisstransplant, Scandiatransplant and British Transplantation Society Networks
Z. Czigany,¹ J. Bednarsch,¹ J. Böcker,¹ F. Meister,¹ I. Amygdalos,¹ W. Schöning,¹ T. Ulmer,¹ X. Rogiers,² P. Dutkowski,³ P-.D. Line,⁴ M. Malagó,⁵ U. Neumann,¹ G. Lurje.¹
¹Department of Surgery and Transplantation, University Hospital RWTH, Aachen, Germany; ²Department of Solid Organ Transplantation, University Hospital Gent, Gent, Belgium; ³Department of Surgery and Transplantation, University Hospital Zurich, Zurich, Switzerland; ⁴Department of Solid Organ Transplantation, University Hospital Oslo, Oslo, Norway; ⁵Department of Hepatobiliary Surgery and Transplantation, University College London, London, United Kingdom.
Background: Surgical aspects of ortoptopic liver transplantation (OLT) are widely based on low-level evidence as well as on local institutional protocols. Aim of this study…
2018 American Transplant Congress
Two Years of the HOPE Act
A. Wilk,¹ C. Durand,² D. Segev,² D. Klassen.¹
¹United Network for Organ Sharing, Richmond, VA; ²Johns Hopkins University, Baltimore, MD.
The HOPE Act allows research on transplantation of organs from HIV+ donors into patients infected with HIV prior to transplantation. There are 42 kidney and…
2018 American Transplant Congress
Race, Income, and Insurance Status Predict Migration for Liver Transplantation in the United States
A. Kwong, A. Mannalithara, W. Kim.
Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA.
Background: Ongoing organ shortage and regional differences in organ availability have encouraged patients in need of liver transplantation (LT) to travel in order to increase…
2018 American Transplant Congress
Impact of Direct Acting Antivirals of Hepatitis C Virus Therapy on Tacrolimus Dosing Post-Liver Transplant
A. Bixby, L. Fitzgerald, R. Leek, J. Mellinger, S. Tischer.
Michigan Medicine, Ann Arbor, MI.
Background: Direct acting antivirals (DAA) have transformed hepatitis C virus (HCV) management post-liver transplant (LT). As HCV clears, hepatic metabolism improves, resulting in decreased tacrolimus…
2018 American Transplant Congress
Demographic and Geographic Differences in the Proportion of Liver Disease Deaths Captured by the Transplant Waitlist in the United States, 2011 – 2015
K. Ross,¹ R. Lynch,² D. Goldberg,³ R. Patzer.^1,2
¹Department of Epidemiology, Rollins School of Public Health, Atlanta, GA; ²Emory Transplant Center, Atlanta, GA; ³Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Background: There are no population-based estimates of the prevalence of end-stage liver disease in the United States, creating challenges in measuring disease burden to inform…
2018 American Transplant Congress
HLA-DR4 Matching and Hepatocellular Carcinoma Recurrence after Liver Transplantation
M. Xu, S. Garcia-Aroz, N. Vachharajani, Y. Lin, W. Chapman.
Department of Surgery, Section of Abdominal Transplantation, Washington University School of Medicine, St. Louis, MO.
PURPOSE: The phenomenon of graft versus host disease after orthotopic liver transplantation (OLT) is estimated at approximately 1-2%, suggesting that under some circumstances, the graft…