2019 American Transplant Congress
CD38 Inhibition: A Novel Target for Hepatic Ischemia Reperfusion Injury
*Purpose: Ischemia/reperfusion injury (IRI) is a major source of injury during many surgical procedures on the liver, and severe IRI can lead to post-hepatectomy liver…2019 American Transplant Congress
Contribution of CD38 to Methionine Choline Deficient (MCD) Diet-Induced Liver Injury in Rats
Department of Cardiac Surgery, The Ohio State Univ. Medical Center, Columbus, OH
*Purpose: Nonalcoholic fatty liver disease (NAFLD) and associated non-alcoholic steatohepatitis (NASH) is a rising cause of end stage liver disease, increasing the need for liver…2019 American Transplant Congress
Drug Metabolizing Capacity Of The Liver In Liver Donors Recovers Fully By One Month Post Donation
*Purpose: In liver donors, hepatic volume recovers to pre donation values in 2-6 months after surgery. However, there is limited information on the recovery of…2019 American Transplant Congress
The lncRNA-mRNA Co-Expression Analysis in Acetaminophen-Induced Liver Injury
*Purpose: Acetaminophen (APAP) could cause liver injury, or even acute liver failure, accounting for approximately one-half of all cases in developed countries. Once acute liver…2018 American Transplant Congress
Hypothermic Machine Perfusion Protects DCD Liver Graft through Metabolism of Xenobiotics by Cytochrome P450 Pathway
Background: Donation after cardiac death (DCD) is the mainly resource to relieve organ-transplantation shortage. Our previous research have confirmed that the function of DCD liver…2017 American Transplant Congress
Clearance of Transaminases During Normothermic Ex Vivo Liver Perfusion.
One of the most promising applications of normothermic ex vivo liver perfusion is the possibility of real-time graft viability assessment. Many liver biomarkers are considered…2017 American Transplant Congress
Porcine Albumin Elaboration During Perfusion of Transgenic Porcine Livers with Human Blood.
PurposeIn addition to immune barriers, molecular incompatibilities between species are predicted to limit pig liver survival in primate xenotransplantation models. How perfusion with human blood…2016 American Transplant Congress
Metabolomic Profiles of Hepatocellular Carcinoma and Cirrhotic Patients Before and After Transplantation.
Metabolomics offers the opportunity to characterize complex diseases like hepatocellular carcinoma (HCC) through a systematic evaluation of thousands of metabolites in human liver tissues and…2016 American Transplant Congress
The Correlation of Hepatic and Systemic Hemodynamics During Liver Transplantation: Quantification of Hepatic Resistance as an Actual Value.
Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
PurposeThe correlation between portal vein pressure (PVP) and flow (PVF) has not been established, and there is still lack of consensus about the optimal hemodynamics…2016 American Transplant Congress
Metabolic Recovery and Ex Vivo Simulation of Early Liver Reperfusion.
Purpose. An urgent need for more liver grafts for transplantation has prompted the use of more suboptimal organs. Particularly in these more marginal livers adequate…