Articles tagged "Liver grafts"

2019 American Transplant Congress
Effects of Omega-3 Fatty Acids on Outcome after Living Donor Right Hepatectomy
S. Lee, J. Kim, G. Choi, J. Joh, S. Lee
Department of Surgery, Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: Preclinical data suggest that supplementation of omega-3 fatty acids may be beneficial in liver resections, by ameliorating ischemic injury during the surgical procedure. In…
2019 American Transplant Congress
Independent Risk Factors for Discard of Pediatric Liver Allografts
T. H. Malik¹, J. Goss², N. T. Galvan², M. L. Kueht II², A. Rana³
¹Department of Student Affairs, Baylor College of Medicine, Houston, TX, ²Department of Abdominal Transplantation, Baylor College of Medicine, Houston, TX, ³Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: The aim of this study is to identify risk factors available at the time of initial DonorNet offer to predict discard of pediatric liver…
2019 American Transplant Congress
Damage-Associated Molecular Pattern Release and Toll-Like Receptor Activation during Cold Storage and Ex Vivo Reperfusion of Old Rat Livers
U. Scheuermann, E. R. Seyferth, M. Zhu, M. Song, J. Yerxa, R. P. Davis, W. Parker, M. Hartwig, J. Kwun, J. Lee, A. S. Barbas
Department of Surgery, Duke University Medical Center, Durham, NC
*Purpose: Donor age is one of the most important predictive factors of graft outcome in liver transplantation. The aim of this study was to investigate…
2019 American Transplant Congress
Discovery and Validation of Blood Genomic Signatures of Acute Rejection in Liver Transplant Recipients
J. Levitsky¹, N. Bridges², J. Odim², M. Brown², D. Ikle³, B. Armstrong³, A. Demetris⁴, S. Asrani⁵, G. Klintmalm⁵, T. Schiano⁶, A. Moss⁷, K. Chavin⁸, C. Miller⁹, M. Kandpal¹⁰, L. Zhao¹⁰, S. Kurian¹¹, M. Abecassis¹⁰
¹Div of Gastroenterology & Comprehensive Tx Cnt, Chicago, IL, ²NIAID, Bethesda, MD, ³Rho, Chapel Hill, NC, ⁴UPMC, Pittsburgh, PA, ⁵Baylor, Dallas, TX, ⁶Mount Sinai, New York, NY, ⁷Mayo Arizona, Phoenix, AZ, ⁸Case Western, Cleveland, OH, ⁹Cleveland Clinic, Cleveland, OH, ¹⁰Comprehensive Transplant Center, Chicago, IL, ¹¹Scripps, San Diego, CA
*Purpose: Biomarker profiles diagnostic of acute rejection (AR) could enhance the management of liver transplant (LT) recipients. Our aim was to discover and validate blood…
2019 American Transplant Congress
Evaluating Liver Regeneration during Normothermic Machine Perfusion in Hepatectomized Rat Liver Model
M. Aburawi¹, S. Mert¹, E. Hafiz², P. Mahboub¹, H. Yeh¹, K. Uygun¹, J. Markmann¹
¹Surgery, Massachusetts General Hospital, Boston, MA, ²Pathology and Electron Microscopy, Theodor Bilharz Research Institute, Cairo, Egypt
*Purpose: Realizing the liver’s unique ability to regenerate, this ongoing study examines Normothermic Machine Perfusion (NMP) as a promising platform for evaluating & potentially simulating…
2019 American Transplant Congress
Liver Allograft Provides Protection Against Cardiac Allograft Rejection In Combined Heart And Liver Transplantation
K. Zhao¹, R. Wang², M. Kamoun³, K. Olthoff¹, M. Hoteit⁴, E. Rame⁵, M. Levine¹, R. Mclean⁵, P. Abt¹
¹Surgery, University of Pennsylvania, Philadelphia, PA, ²Jefferson University, Philadelphia, PA, ³Pathology, University of Pennsylvania, Philadelphia, PA, ⁴Gastroenterology, University of Pennsylvania, Philadelphia, PA, ⁵Cardiology, University of Pennsylvania, Philadelphia, PA
*Purpose: Combined heart-liver transplant (CHLT) is indicated for patients with combination of heart and liver disease or amyloid heart disease for whom liver transplant can…
2019 American Transplant Congress
The Centennial Allograft? Observation Of Greater Than 100-year Allograft Survival Is More Common Among Liver Allograft Recipients Than Renal Allograft Recipients.
J. F. Renz, A. C. Gruessner, R. C. Misawa, A. Masi, R. W. Gruessner
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: We investigated the occurrence of deceased-donor liver (DDOLT), deceased-donor renal (DDRT), and living-donor renal allografts (LDRT) that have achieved 100 years or more of…
2019 American Transplant Congress
Histologic Ischemia Reperfusion Injury in Liver Transplantation: A Large Single Center Experience
F. M. Kaldas, T. Ito, S. Younan, J. Aziz, M. Lu, V. G. Agopian, J. DiNorcia III, H. Yersiz, D. G. Farmer, R. W. Busuttil
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Ischemia Reperfusion Injury (IRI) is known to adversely affect graft outcomes in Liver Transplantation (LT). Large series examining the significance of IRI found on…
2019 American Transplant Congress
Clinical Impact of Spontaenous Portosystemic Shunts on the Short Term Outcome of Liver Transplantation
E. A. Rodriguez¹, R. M. Perez², N. Zhang³, E. S. Lim³, C. R. Miller⁴, M. A. Schwartz², A. J. McGirr⁴, A. Srinivasan⁵, W. R. Hewitt⁵, A. C. Silva⁴, J. Rakela¹, H. E. Vargas¹
¹Transplant Hepatology, Mayo Clinic Arizona, Phoenix, AZ, ²Mayo Clinic School of Medicine, Mayo Clinic Arizona, Phoenix, AZ, ³Division of Health Sciences Research, Mayo Clinic Arizona, Phoenix, AZ, ⁴Radiology, Mayo Clinic Arizona, Phoenix, AZ, ⁵Transplant Surgery, Mayo Clinic Arizona, Phoenix, AZ
*Purpose: The aim of our study was to compare Liver Transplant (LT) candidates with and without spontaneous portosystemic shunts (SPSS) and assess their impact on…
2019 American Transplant Congress
Notch1 Signaling Protects Liver Grafts from Ischemia Reperfusion Injury: From Mouse to Human
K. Kadono, S. Kageyama, H. Hirao, K. Nakamura, T. Ito, K. J. Dery, D. Oncel, B. Ke, F. M. Kaldas, R. W. Busuttil, J. W. Kupiec‐Weglinski
Surgery, Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: The clinical relevance and tissue-specific role of Notch1 activation, a highly conserved transmembrane receptor involved in cell fate decision, proliferation and regeneration, in orthotopic…

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