2019 American Transplant Congress
Evaluating Liver Regeneration during Normothermic Machine Perfusion in Hepatectomized Rat Liver Model
*Purpose: Realizing the liver’s unique ability to regenerate, this ongoing study examines Normothermic Machine Perfusion (NMP) as a promising platform for evaluating & potentially simulating…2019 American Transplant Congress
Liver Allograft Provides Protection Against Cardiac Allograft Rejection In Combined Heart And Liver Transplantation
*Purpose: Combined heart-liver transplant (CHLT) is indicated for patients with combination of heart and liver disease or amyloid heart disease for whom liver transplant can…2019 American Transplant Congress
The Centennial Allograft? Observation Of Greater Than 100-year Allograft Survival Is More Common Among Liver Allograft Recipients Than Renal Allograft Recipients.
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: We investigated the occurrence of deceased-donor liver (DDOLT), deceased-donor renal (DDRT), and living-donor renal allografts (LDRT) that have achieved 100 years or more of…2019 American Transplant Congress
Histologic Ischemia Reperfusion Injury in Liver Transplantation: A Large Single Center Experience
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Ischemia Reperfusion Injury (IRI) is known to adversely affect graft outcomes in Liver Transplantation (LT). Large series examining the significance of IRI found on…2019 American Transplant Congress
Clinical Impact of Spontaenous Portosystemic Shunts on the Short Term Outcome of Liver Transplantation
*Purpose: The aim of our study was to compare Liver Transplant (LT) candidates with and without spontaneous portosystemic shunts (SPSS) and assess their impact on…2019 American Transplant Congress
Notch1 Signaling Protects Liver Grafts from Ischemia Reperfusion Injury: From Mouse to Human
Surgery, Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: The clinical relevance and tissue-specific role of Notch1 activation, a highly conserved transmembrane receptor involved in cell fate decision, proliferation and regeneration, in orthotopic…2019 American Transplant Congress
Utilization of DCD Donors >50 Years Old for Liver Transplantation
Arizona Transplant Associates, PC, Phoenix, AZ
*Purpose: End stage liver disease is becoming more prevalent in the United States with approximately 4.9 million adults carrying the diagnosis. It is estimated that…2019 American Transplant Congress
Incidence and Risks for Non-alcoholic Fatty Liver Disease and Steatohepatitis Post Liver Transplant: Systematic Reveiw and Meta-Analysis
1Beaumont Hospital, Ann Arbor, MI, 2University of Michigan, Ann Arbor, MI
*Purpose: Recurrent and denovo non-alcoholic fatty liver (NAFLD) and non-alcoholic steatohepatitis (NASH) are important post-liver transplant (LT) outcomes given risk to graft viability. The true…2019 American Transplant Congress
Early Allograft Dysfunction in the Setting of Histologic Ischemia Reperfusion Injury Following Liver Transplantation: Analysis of Predictors and Outcomes
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Hepatic ischemia-reperfusion injury (IRI) in Liver Transplantation (LT) is believed to contribute to Early Allograft Dysfunction (EAD). However, the relationship between IRI and EAD…2019 American Transplant Congress
CEACAM1 – p38 Signaling Axis Alleviates Peri-Transplant Liver Injury: From Mouse-to-Human
1UCLA, Los Angeles, CA, 2City of Hope, Duarte, CA
*Purpose: Although CEACAM1 (CM1; carcinoembryonic antigen-related cell adhesion molecule 1; CD66a) regulates hepatic metabolism, its role in orthotopic liver transplantation (OLT) is unknown. A recent…
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