2020 American Transplant Congress
Transplant Center Effect on Acute Liver Failure Outcomes in a National Cohort
University of Pennsylvania, Philadelphia, PA
*Purpose: Transplant centers coordinate complex care for patients with acute liver failure (ALF), in whom liver transplantation (LT) can be lifesaving. This study examines associations…2020 American Transplant Congress
Acute on Chronic Liver Failure (ACLF) Patients Have a Dynamic and Progressive Clinical Course Until Receiving a Liver Transplant: A 5-Year Study at the National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico
*Purpose: To characterize the clinical course of patients diagnosed with acute on chronic liver failure (ACLF) before undergoing liver transplantation. ACLF is characterized by an…2020 American Transplant Congress
Galectin-3 as a Biomarker of Disease Severity in Acute-on-Chronic Liver Failure
*Purpose: A matter of great importance is the discovery of alternative diagnostic measures that can detect liver disease at an early stage, especially when at…2020 American Transplant Congress
Rare Genetic Mutation Triggering Acute Liver Failure in a Toddler Needing a Liver Transplant
1Cleveland Clinic, Cleveland, OH, 2Akron Children's Hospital, Akron, OH
*Purpose: The AIRE gene plays an important role in immune tolerance by driving negative selection of self-recognizing T-cells. Mutations in this gene are responsible for…2020 American Transplant Congress
In a Murine Model of Acetaminophen-Mediated Liver Injury, Tubastatin-a, An Hdac6-Specific Inhibitor, Improves Survival and Decreases Hepatocellular Injury
*Purpose: Tylenol (APAP) toxicity, due to its narrow therapeutic window, is the leading cause of acute liver failure in the United States, resulting in approximately…2020 American Transplant Congress
Ex-Vivo Perfusion with UW Cold Storage Solution Improves DCD Rat Liver Preservation
Surgery, Virginia Commonwealth University, Richmond, VA
*Purpose: The donor pool of livers can be expanded by the successful use of donor livers recovered under DCD conditions. It is assumed that perfusion…2020 American Transplant Congress
Karnofsky Performance Status Significantly Increases Waitlist Mortality among Different Grades of Acute on Chronic Liver Failure
1Cedars Sinai Medical Center, Los Angeles, CA, 2Alameida Health System, Oakland, CA
*Purpose: Acute on chronic liver failure (ACLF) is a condition associated with high waitlist mortality and graded according to the number of organ system failures…2020 American Transplant Congress
Improved Survival of Acute Liver Failure by “Off-the-Shelf” Bioartificial Liver Support System Using Immobilized Cryopreserved Hepatocyte Spheroids in Porcine Model
*Purpose: Acute liver failure (ALF) has a rapid and unpredictable onset with high mortality. The only current treatment is to transplant a donor organ but…2020 American Transplant Congress
Comparison of Clinical Outcomes of Induction Regimens in Patients Undergoing Liver Transplantation for Acute Liver Failure
*Purpose: Spontaneous survival rates in acute liver failure (ALF) are vastly improved by liver transplantation (LT). However, the value of induction agents beyond steroids continues…2020 American Transplant Congress
Rare Case of Donor Transmission of Hepatitis a Virus in Two Kidney Transplant Recipients
University of Virginia, Charlottesville, VA
*Purpose: Infectious transmission via solid organ transplant (SOT) remains an inherent risk of transplantation despite measures to mitigate the risk. We report a rare case…
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