Articles tagged "Liver failure"

2021 American Transplant Congress
Outcomes of Transjugular Intrahepatic Portosystemic Shunts (TIPS) in Dialysis-Dependent ESLD Patients: The ALTA Study
J. Ge¹, J. Boike², M. German³, G. J. Morelli⁴, E. Spengler³, A. Said³, A. S. Lee³, A. Hristov³, A. Desai⁵, T. Couri⁶, S. Paul⁶, C. Frenette⁷, N. Christian-Miller⁷, M. Laurito⁸, E. Verna⁸, U. Rahim⁹, A. Goel⁹, D. Gregory², L. VanWagner², K. P. Kolli¹, J. Lai¹
¹University of California, San Francisco, San Francisco, CA, ²Northwestern Memorial Hospital, Chicago, IL, ³University of Wisconsin, Madison, WI, ⁴University of Florida Health, Gainsville, FL, ⁵Indiana University School of Medicine, Indianapolis, IN, ⁶University of Chicago, Chicago, IL, ⁷The Scripps Clinic, La Jolla, CA, ⁸Columbia University, New York, NY, ⁹Stanford University, Stanford, CA
*Purpose: Data on the outcomes of patients with cirrhosis who require renal replacement therapy (RRT) at the time of transjugular intrahepatic portosystemic shunts (TIPS) is…
2021 American Transplant Congress
Improved Outcomes Over Time of Extended Criteria Donor Grafts for Acute-on-chronic Liver Failure
T. Kitajima, T. Ivanics, D. Moonka, T. Shamaa, A. Mohamed, K. Delvecchio, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai
Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI
*Purpose: Given the high waitlist mortality of patients with acute-on-chronic liver failure (ACLF), liver transplant (LT) with an extended criteria donor (ECD) can be considered.…
2021 American Transplant Congress
Neutrophil Extracellular Trap-induced Thrombotic Microangiopathy in Steatotic Mouse Recipients Impacts Liver Transplant Outcomes
H. Hirao, H. Kojima, K. Kadono, K. J. Dery, D. G. Farmer, F. M. Kaldas, J. W. Kupiec-Weglinski
UCLA Medical Center, Los Angeles, CA
*Purpose: Nonalcoholic steatohepatitis (NASH) is an emerging global epidemic projected to become the leading indication for liver transplantation (LT). Although recent studies focus on the…
2021 American Transplant Congress
Iatrogenic Sodium Exposure in Hospitalized Patients with Liver Disease
P. Klem¹, R. Mbangu Kot Mbau², B. Crowther¹, V. Lewis¹, S. Lin¹, E. Patrick³, A. Nadrash¹, K. Schoeppler¹, I. Kim¹
¹Pharmacy, University of Colorado Hospital, Aurora, CO, ²Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, ³Transplant Services, University of Colorado Hospital, Aurora, CO
*Purpose: Numerous medications administered in the hospital setting may contain hidden/additional amounts of sodium in the drug itself and via intravenous (IV) diluents or admixtures.…
2021 American Transplant Congress
Simultaneous Heart-Liver-Kidney Transplantation Survival: National and Single-Center Outcomes
U. A. Siddiqi¹, P. S. Combs¹, G. Kim², T. Baker³, Y. Becker¹, V. Jeevanandam¹
¹Section of Cardiac Surgery, University of Chicago Medicine, Chicago, IL, ²Section of Cardiology, University of Chicago Medicine, Chicago, IL, ³University of Chicago Medicine, Chicago, IL
*Purpose: Simultaneous Heart-Liver-Kidney transplantation (SHLKTx) is an incredibly rare, high-risk operation undergone by well-selected patients presenting with multi-organ failure. Our center has performed 10 of…
2021 American Transplant Congress
A Shift in Paradigm: Phosphatidylethanol Testing to Monitor for and Address Alcohol Recidivism Following Liver Transplantation
F. M. Nimri¹, S. Naffouj¹, F. Askar¹, A. Singh², H. Gonzalez², S. Jafri²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI, ²Gastroenterology, Henry Ford Hospital, Detroit, MI
*Purpose: Phosphatidylethanol (PEth) is a phospholipid that forms in the presence of ethanol with a long half-life compared to other alcohol detection tests. PEth testing…
2021 American Transplant Congress
SARS-CoV-2 Infection in Solid Organ Transplant Recipients: A Retrospective Cohort Study
A. Adeel
Infectious Diseases, University of Massachusetts, Worcester, MA
*Purpose: Initial studies of COVID-19 in solid organ transplant (SOT) recipients demonstrated high mortality rates, but more recent comparative data shows contradictory results.*Methods: We evaluated…
2020 American Transplant Congress
Karnofsky Performance Status Significantly Increases Waitlist Mortality among Different Grades of Acute on Chronic Liver Failure
A. Ashhab¹, R. Wong², V. Sundaram¹
¹Cedars Sinai Medical Center, Los Angeles, CA, ²Alameida Health System, Oakland, CA
*Purpose: Acute on chronic liver failure (ACLF) is a condition associated with high waitlist mortality and graded according to the number of organ system failures…
2020 American Transplant Congress
Improved Survival of Acute Liver Failure by “Off-the-Shelf” Bioartificial Liver Support System Using Immobilized Cryopreserved Hepatocyte Spheroids in Porcine Model
S. Lee¹, J. Lee², H. Park², Y. Kim², J. Noh³, J. Jung³, S. Lee³, H. Shin³, H. Yoon⁴, D. Lee³, S. Lee¹
¹Department of Surgery, Samsung Medical Center, Seoul, Korea, Republic of, ²Stem Cell and Regenerative Medicine Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, Korea, Republic of, ³Biomedical Research Center, Lifeliver, Co. Ltd., Yongin, Korea, Republic of, ⁴Biomedical Research Center, Lifeliver, Co. Ltd., Seoul, Korea, Republic of
*Purpose: Acute liver failure (ALF) has a rapid and unpredictable onset with high mortality. The only current treatment is to transplant a donor organ but…
2020 American Transplant Congress
Comparison of Clinical Outcomes of Induction Regimens in Patients Undergoing Liver Transplantation for Acute Liver Failure
C. M. Anugwom¹, J. Parekh², C. Hwang³, M. MacConmara³, W. M. Lee⁴, T. M. Leventhal¹
¹Gastroenterology, Hepatology and Nutrition, University of Minnesota Medical Center, Minneapolis, MN, ²Department of Surgery, University of California, San Diego, San Diego, CA, ³Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, ⁴Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX
*Purpose: Spontaneous survival rates in acute liver failure (ALF) are vastly improved by liver transplantation (LT). However, the value of induction agents beyond steroids continues…