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Articles tagged "Liver cirrhosis"

  • 2022 American Transplant Congress

    Escalating Waitlist Mortality Above MELD 40: A Rationale to Uncap MELD 3.0?

    A. Kwong, A. Mannalithara, W. Kim

    Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA

    *Purpose: MELD 3.0 is a recently proposed model that improves upon MELD-Na, incorporating sex and albumin as additional variables, updating existing coefficients and adding relevant…
  • 2022 American Transplant Congress

    Identifying Predictors of Pediatric Heart Only versus Combined Heart-Liver Transplantation

    K. Zhang, S. Chen, A. Syed, A. Gallo, C. Esquivel, C. Bonham, S. Hollander, M. Ma, J. Han, N. Ebel

    Stanford University, Stanford, CA

    *Purpose: A standardized protocol to identify which patients with Fontan failure require combined heart liver transplant (cHLT) versus isolated heart transplant (HT) has not yet…
  • 2021 American Transplant Congress

    Transplant-free Survival in Alcohol-related Liver Disease (ALD) Patients Presenting with First Evidence of Ascites

    K. Fahoum1, N. T. Shen2, E. Basu1, J. Lee3, A. Kaplan2, A. Salajegheh4, R. Rosenblatt2, A. Jesudian2, C. Lucero2, B. Fortune2, M. M. Safford5, R. S. Brown2

    1Medical College, Weill Cornell Medicine, New York, NY, 2Gastroenterology and Hepatology, Weill Cornell Medicine, New York, NY, 3Population Health Sciences, Weill Cornell Medicine, New York, NY, 4Psychiatry, Weill Cornell Medicine, New York, NY, 5General Internal Medicine, Weill Cornell Medicine, New York, NY

    *Purpose: The development of ascites is a poor prognostic sign for patients with cirrhosis. The factors associated with transplant-free survival at initial presentation with ascites…
  • 2021 American Transplant Congress

    Identification of Molecular Markers for Liver Cirrhosis by Single-nucleus Rna Sequencing

    C. Kuscu1, C. Kuscu1, M. Akram2, A. Shetty3, D. G. Maluf4, J. Eason1, V. Mas5

    1Surgery, James D Eason Transplat Institute, Memphis, TN, 2Surgery, Center for Biomedical Informatics, Memphis, TN, 3Surgery, Institute for Genome Sciences, School of Medicine, Baltimore, MD, 4Surgery, Program in Transplantation University of Maryland, Baltimore, MD, 5Surgery, Division of Surgical Science University of Maryland, Baltimore, MD

    *Purpose: Non-alcoholic fatty liver disease (NAFLD) is characterized by metabolic syndrome and the accumulation of fat in the liver cells (hepatocytes) leading to inflammation and…
  • 2021 American Transplant Congress

    Algorithms to Identify Alcoholic Hepatitis Hospitalizations in Patients with Cirrhosis

    S. Panchal1, D. Kaplan2, D. Goldberg3, N. Mahmud2

    1Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 2Gastroenterology, Hospital of the University of Pennsylvania, Philadelphia, PA, 3Gastroenterology, University of Miami Miller School of Medicine, Miami, FL

    *Purpose: With the rising proportion of patients receiving liver transplantation for alcoholic hepatitis, it is important to identify methods of ascertaining hospitalizations with alcoholic hepatitis…
  • 2021 American Transplant Congress

    Longitudinal Quality of Life Assessment in Liver Transplant – Feasibility Study and Early Results

    O. M. Siddiqui, P. Polineni, A. J. Thuluvath, C. Loftus

    Northwestern University, Chicago, IL

    *Purpose: In addition to survival, quality of life (QoL) is critical to optimizing care in liver transplantation (LT). Although QoL is associated with clinical outcomes…
  • 2021 American Transplant Congress

    A Shift in Paradigm: Phosphatidylethanol Testing to Monitor for and Address Alcohol Recidivism Following Liver Transplantation

    F. M. Nimri1, S. Naffouj1, F. Askar1, A. Singh2, H. Gonzalez2, S. Jafri2

    1Internal Medicine, Henry Ford Hospital, Detroit, MI, 2Gastroenterology, Henry Ford Hospital, Detroit, MI

    *Purpose: Phosphatidylethanol (PEth) is a phospholipid that forms in the presence of ethanol with a long half-life compared to other alcohol detection tests. PEth testing…
  • 2021 American Transplant Congress

    The Rate of Hospitalization Among Patients with Cirrhosis is More Than Twice as High as Patients Over 85 Years

    N. R. Mazumder1, K. Guo2, L. Zhao3, A. Kho1, K. Walters4, T. S. Carey4, C. Loftus1, D. P. Ladner1

    1Northwestern Memorial Hospital, Chicago, IL, 2Biostatistics, Northwestern Memorial Hospital, Chicago, IL, 3Biostatistcs, Northwestern Memorial Hospital, Chicago, IL, 4University of North Carolina Chapel Hill, Chapel Hill, NC

    *Purpose: Cirrhosis is a common disease however it is understudied because population data on patients with cirrhosis is lacking. While the risk of hospitalization in…
  • 2021 American Transplant Congress

    The Role of Histone Acetylation/methylation Mediated Epigenetic Modifications in the Pathogenesis of Non-alcoholic Steatohepatitis-associated Liver Carcinogenesis

    P. K. Rajan1, U. Utibe-Abasi1, J. D. Sanabria1, M. Banerjee2, G. Smith1, M. S. Schade1, J. Sanabria1, K. Sodhi1, S. Pierre2, Z. Xie2, J. I. Shapiro2, J. Sanabria1

    1Department of Surgery, Marshall University, Huntington, WV, 2Marshall Institute for Interdisciplinary Research (MIIR), Marshall University, Huntington, WV

    *Purpose: Hepatocellular carcinoma (HCC) is one of the most aggressive human cancers and is characterized by an acquisition of multiple abnormal phenotypes driven by epigenetic…
  • 2021 American Transplant Congress

    Outcomes of Transjugular Intrahepatic Portosystemic Shunts (TIPS) in Dialysis-Dependent ESLD Patients: The ALTA Study

    J. Ge1, J. Boike2, M. German3, G. J. Morelli4, E. Spengler3, A. Said3, A. S. Lee3, A. Hristov3, A. Desai5, T. Couri6, S. Paul6, C. Frenette7, N. Christian-Miller7, M. Laurito8, E. Verna8, U. Rahim9, A. Goel9, D. Gregory2, L. VanWagner2, K. P. Kolli1, J. Lai1

    1University of California, San Francisco, San Francisco, CA, 2Northwestern Memorial Hospital, Chicago, IL, 3University of Wisconsin, Madison, WI, 4University of Florida Health, Gainsville, FL, 5Indiana University School of Medicine, Indianapolis, IN, 6University of Chicago, Chicago, IL, 7The Scripps Clinic, La Jolla, CA, 8Columbia University, New York, NY, 9Stanford University, Stanford, CA

    *Purpose: Data on the outcomes of patients with cirrhosis who require renal replacement therapy (RRT) at the time of transjugular intrahepatic portosystemic shunts (TIPS) is…
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