Articles tagged "Liver cirrhosis"

2022 American Transplant Congress
Liver Transplantation is Beneficial Regardless of Cirrhosis Stage or Acute-on-Chronic Liver Failure Grade: A Single-Center Experience
E. Cervantes-Alvarez, O. Mendez-Guerrero, D. Kershenobich, A. Torre, M. Vilatobá, N. Navarro-Alvarez
Gastroenterology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
*Purpose: Liver transplantation for the most critically ill remains controversial; however, it is currently the only curative treatment option. The aim of this study was…
2022 American Transplant Congress
Molecular Characterization of Progressive Fibrosis in the Liver by Single-Nuclei RNA Sequencing
T. Rousselle¹, J. McDaniels¹, A. Shetty¹, E. Bardhi¹, D. Polsky¹, E. Williams¹, D. Maluf², V. Mas¹
¹Surgical Sciences, University of Maryland Baltimore, Baltimore, MD, ²Transplantation Program, University of Maryland Medical Center, Baltimore, MD
*Purpose: The prevalence of obesity is negatively affecting the availability of livers for transplantation. Non-alcoholic fatty liver disease (NAFLD) is associated with an increase in…
2021 American Transplant Congress
A Shift in Paradigm: Phosphatidylethanol Testing to Monitor for and Address Alcohol Recidivism Following Liver Transplantation
F. M. Nimri¹, S. Naffouj¹, F. Askar¹, A. Singh², H. Gonzalez², S. Jafri²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI, ²Gastroenterology, Henry Ford Hospital, Detroit, MI
*Purpose: Phosphatidylethanol (PEth) is a phospholipid that forms in the presence of ethanol with a long half-life compared to other alcohol detection tests. PEth testing…
2021 American Transplant Congress
The Rate of Hospitalization Among Patients with Cirrhosis is More Than Twice as High as Patients Over 85 Years
N. R. Mazumder¹, K. Guo², L. Zhao³, A. Kho¹, K. Walters⁴, T. S. Carey⁴, C. Loftus¹, D. P. Ladner¹
¹Northwestern Memorial Hospital, Chicago, IL, ²Biostatistics, Northwestern Memorial Hospital, Chicago, IL, ³Biostatistcs, Northwestern Memorial Hospital, Chicago, IL, ⁴University of North Carolina Chapel Hill, Chapel Hill, NC
*Purpose: Cirrhosis is a common disease however it is understudied because population data on patients with cirrhosis is lacking. While the risk of hospitalization in…
2021 American Transplant Congress
The Role of Histone Acetylation/methylation Mediated Epigenetic Modifications in the Pathogenesis of Non-alcoholic Steatohepatitis-associated Liver Carcinogenesis
P. K. Rajan¹, U. Utibe-Abasi¹, J. D. Sanabria¹, M. Banerjee², G. Smith¹, M. S. Schade¹, J. Sanabria¹, K. Sodhi¹, S. Pierre², Z. Xie², J. I. Shapiro², J. Sanabria¹
¹Department of Surgery, Marshall University, Huntington, WV, ²Marshall Institute for Interdisciplinary Research (MIIR), Marshall University, Huntington, WV
*Purpose: Hepatocellular carcinoma (HCC) is one of the most aggressive human cancers and is characterized by an acquisition of multiple abnormal phenotypes driven by epigenetic…
2021 American Transplant Congress
Outcomes of Transjugular Intrahepatic Portosystemic Shunts (TIPS) in Dialysis-Dependent ESLD Patients: The ALTA Study
J. Ge¹, J. Boike², M. German³, G. J. Morelli⁴, E. Spengler³, A. Said³, A. S. Lee³, A. Hristov³, A. Desai⁵, T. Couri⁶, S. Paul⁶, C. Frenette⁷, N. Christian-Miller⁷, M. Laurito⁸, E. Verna⁸, U. Rahim⁹, A. Goel⁹, D. Gregory², L. VanWagner², K. P. Kolli¹, J. Lai¹
¹University of California, San Francisco, San Francisco, CA, ²Northwestern Memorial Hospital, Chicago, IL, ³University of Wisconsin, Madison, WI, ⁴University of Florida Health, Gainsville, FL, ⁵Indiana University School of Medicine, Indianapolis, IN, ⁶University of Chicago, Chicago, IL, ⁷The Scripps Clinic, La Jolla, CA, ⁸Columbia University, New York, NY, ⁹Stanford University, Stanford, CA
*Purpose: Data on the outcomes of patients with cirrhosis who require renal replacement therapy (RRT) at the time of transjugular intrahepatic portosystemic shunts (TIPS) is…
2021 American Transplant Congress
Home-based Liver Frailty Intervention (lift) in Liver Transplant Candidates: A Pilot Study
A. J. Thuluvath¹, K. Belfanti¹, S. Morrissey¹, O. Siddiqui¹, J. Peipert¹, A. Daud¹, J. Levitsky¹, T. Bogg², A. Flores¹, D. P. Ladner¹
¹Northwestern University Transplant Research Collaborative, Chicago, IL, ²Department of Psychology, Wayne State University, Detroit, MI
*Purpose: Frailty is highly prevalent in patients awaiting LT and is associated with increased waitlist and post-transplant mortality, hospitalizations and LOS. While reduction of frailty…
2021 American Transplant Congress
Kidney Transplantation Alone in Patients with Compensated Cirrhosis: A Multicenter Study
A. Kassem¹, S. Asrani¹, S. W. Biggins², Y. Darwish¹, M. Nadim³, B. Fischbach¹, T. Fong³
¹Baylor University Medical Center at Dallas, Dallas, TX, ²University of Washington, Seattle, WA, ³USC - Keck, Los Angeles, CA
*Purpose: Patients undergoing kidney transplant (KTA) often have risk factors for liver disease including viral hepatitis and non-alcoholic fatty liver disease (NAFLD). Recent European Association…
2021 American Transplant Congress
Severe Hypoxemia After Liver Transplantation in the Hepatopulmonary Syndrome
J. Doi, M. Fujiki, G. DAmico, K. Sasaki, T. Diago, F. Aucejo, C. Kwon, B. Eghtesad, K. Hashimoto, C. Miller, Q. Cristiano
Cleveland Clinic, Cleveland, OH
*Purpose: Hepato-pulmonary syndrome (HPS) is a complication of liver disease with liver transplantation as the only curative treatment. However these patients can develop severe hypoxemia…
2021 American Transplant Congress
Assessing the Prevalence of Risk Factors for Osteoporosis and Rate of Screening by Dexa Scan in Patients Referred for Liver Transplant Evaluation
A. France¹, J. Kirk², M. Dokus², B. Al-Judaibi², M. Laryea²
¹Department of Internal Medicine, University of Rochester Medical Center, Rochester, NY, ²Division of Gastroenterology and Hepatology, University of Rochester Medical Center, Rochester, NY
*Purpose: Osteoporosis (OP) and fragility fractures are well-known complications of both chronic liver disease (CLD) and transplant, with a significant increase in the prevalence of…