ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Lipids"

  • 2016 American Transplant Congress

    CMV-Accelerated Cardiac Allograft Rejection Is Associated with Dysregulation of Sphingolipid Metabolomics.

    J. Burg,1 T. Andoh,2 N. Haese,2 C. Kreklywich,2 K. Watters,3 T. Metz,3 S. Orloff,1 D. Streblow.2

    1Abdominal Organ Transplantation, OHSU, Portland, OR; 2VGTI, OHSU, Portland, OR; 3Biological Sciences Division, PNNL, Richland, WA.

    PurposeCytomegalovirus (CMV) infection accelerates transplant vascular sclerosis (TVS) and chronic rejection (CR) in solid organ transplants. Sphingolipid metabolism plays an immunomodulatory role in transplant rejection,…
  • 2016 American Transplant Congress

    Higher Pre-Transplant HDL Levels Are Associated with Decreased Acute Rejection Following Kidney Transplant.

    J. Hagopian,1 D. Brennan,2 K. Lentine,3 T. Horwedel.1

    1Barnes Jewish Hospital, St. Louis; 2Washington University, St. Louis; 3Saint Louis University Center for Transplant Research, St. Louis.

    Purpose: Dyslipidemia is a common comorbidity in patients on the transplant waitlist and post-transplant, and hyperlipidemia has been associated with more robust immune response, possibly…
  • 2016 American Transplant Congress

    Ex-Vivo Normothermic Perfusion (EVNP) Attenuation of Kidney Ischemia-Reperfusion Injury (IRI): A Proposed Mechanism.

    I. Palma,1 S. Kabagambe,1 Y. Smolin,1 T. Boyer,1 I. Palma,1 O. Fiehn,2 Y.-J. Chen,1 J. Sageshima,1 C. Santhanakrishnan,1 C. Troppmann,1 R. Perez.1

    1Department of Surgery, University of California, Davis Medical Center, Sacramento, CA; 2Department of Molecular and Cellular Biology & Genome Center, University of California-Davis, Davis, CA.

    Introduction: EVNP has the potential to repair deceased donor renal IRI. We hypothesize that EVNP may attenuate renal IRI via alteration of lipid metabolism.Methods: Eight…
  • 2015 American Transplant Congress

    ABCB1 Haplotypes, Sex, Calcineurin Inhibitors and Lipid Profiles Post-Renal Transplant

    C. Meaney,1,2 R. Venuto,3 D. Brazeau,4 J. Consiglio,5 L. Cooper,1 G. Wilding,5 K. Tornatore.1,2,3

    1NYS Center of Excellence in Bioinformatics and Life Sciences, Buffalo, NY; 2School of Pharmacy, Buffalo, NY; 3Medicine, School of Medicine, Buffalo, NY; 4University of New England College of Pharmacy, Portland, ME; 5Biostatistics, School of Public Health, University at Buffalo, Buffalo, NY.

    Purpose: Hyperlipidemia is common in renal transplant recipients (RTR) during calcineurin inhibitor (CNI) immunosuppression. P-glycoprotein (P-gp) is an efflux transporter encoded by ABCB1 that modulates…
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