Articles tagged "Kidney"

2019 American Transplant Congress
One Study: A Consortium Model of Clinical Trials Optimized for Comparing New Immune Therapies via Centralized Immune Monitoring
B. Sawitzki¹, S. Schlickeiser¹, M. Streitz¹, K. Jürchott¹, J. Hutchinson², E. Geissler², P. Investigators³
¹Charite Universitätsmedizin, Berlin, Germany, ²University of Regensburg, Regensburg, Germany, ³ONE Study Consortium, EU, Germany
*Purpose: Immune regulatory cell subpopulations can potentially control immune responses to allow immunosuppression (IS) drug minimization. In the ONE Study, an EU FP7-funded research group…
2019 American Transplant Congress
Simulated Tier Variability
N. Salkowski, A. Wey, J. Snyder
SRTR, Minneapolis, MN
*Purpose: The Scientific Registry of Transplant Recipients semi-annually assigns transplant programs to one of five performance tiers for 1-year graft survival in its program-specific reports…
2019 American Transplant Congress
Infectious Complications in Tocilizumab-Treated Kidney Transplant Recipients
S. Sethi, A. Peng, R. Najjar, A. Vo, S. Jordan, E. Huang
Cedars Sinai Medical Center, Los Angeles, CA
*Purpose: Tocilizumab blocks IL-6 signaling, inhibiting maturation of B cells to plasma cells and antibody production. We have used tocilizumab since 2012 to treat kidney…
2019 American Transplant Congress
Dialysis Facility Provider Transplant Knowledge after a Randomized Multilevel Intervention to Increase Kidney Transplant Referral and Evaluation in the Southeast
K. Maroney¹, R. Hamoda¹, L. McPherson¹, A. Cruz², S. Pastan¹, L. Plantinga¹, S. Paul¹, M. Ellis³, D. DuBay⁴, A. Reeves-Daniel⁵, R. Detwiler⁶, E. Hartmann⁷, H. Jones⁸, B. Thrasher⁹, C. Zayas¹⁰, L. Mulloy¹⁰, S. Wright¹¹, R. Patzer¹
¹Emory University, Atlanta, GA, ²IPRO Network of the South Atlantic, Raleigh, NC, ³Duke University, Durham, NC, ⁴Medical University of South Carolina, Charleston, SC, ⁵Wake Forest Health Transplant Center, Winston-Salem, NC, ⁶UNC Center for Transplantation, Chapel Hill, NC, ⁷Piedmont Transplant Institute, Atlanta, GA, ⁸Vidant Medical Center Transplant Services, Greenville, NC, ⁹Carolinas Transplant Center, Charlotte, NC, ¹⁰Augusta University, Augusta, GA, ¹¹IPRO Network of the South Atlantic, Morrisville, NC
*Purpose: Dialysis facility provider kidney transplantation (KTx) knowledge influences patient transplant access. The Reducing Disparities in Access to kidNey Transplantation (RaDIANT) Regional Study is a…
2019 American Transplant Congress
Automated Histology Lesion Interpretation in Kidney Transplant Biopsies Shows That Pathologists Often Deviate from Banff Guidelines
K. S. Madill-Thomsen¹, J. Reeve², G. Bohmig³, F. A. Eskandary⁴, A. Perkowska-Ptasinska⁵, M. Myslak⁶, P. F. Halloran and the INTERCOMEX Study Group¹
¹University of Alberta, Edmonton AB, AB, Canada, ²Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ³Medical University of Vienna, Vienna, Austria, ⁴Medical University of Vienna, Edmonton AB, AB, Canada, ⁵Medical University of Warsaw, Warsaw, Poland, ⁶Pomeranian Medical University, Szczecin, Poland
*Purpose: Histologic diagnosis of kidney transplant biopsies requires an expert pathologist using Banff guidelines to interpret features. Some problematic guidelines require experts to use professional…
2019 American Transplant Congress
No Plan is a Bad Plan! Results of the American Society of Transplantation (AST) Living Donor Community of Practice Mortality Workgroup Survey on Disaster Planning Following a Living Donor Death
M. L. Henderson¹, S. E. Van Pilsum Rasmussen¹, M. M. Waldram¹, K. L. Lentine², D. A. Mandelbrot³, R. L. Hays³, D. G. Maluf⁴, M. Cooper⁵
¹Johns Hopkins, Baltimore, MD, ²Saint Louis University, St Louis, MO, ³University of Wisconsin, Madison, WI, ⁴University of Tennessee, Memphis, TN, ⁵Georgetown University, Washington, DC
*Purpose: The risk of perioperative mortality following living kidney and liver donation, although extremely low, must not be considered a ‘never event’. While the risks…
2019 American Transplant Congress
Kidney Volumes in Healthy Donors – Does Size Really Matter?
F. R. Schwartz¹, B. I. Shaw², F. Vernuccio¹, F. Rigiroli¹, F. Gonzalez¹, R. Lerebours³, K. Ravindra², D. Marin¹
¹Radiology, Duke University, Durham, NC, ²General Surgery, Duke University, Durham, NC, ³Biostatistics and Bioinformatics, Duke University, Durham, NC
*Purpose: To assess the relationship between craniocaudal renal diameters and renal volumes, as well as the frequency of appropriate renal selection for transplant using conventional…
2019 American Transplant Congress
Beneficial Association between Renin-Angiotensin-Aldosterone-System Blockade Usage and Graft Prognosis in Allograft Immunoglobulin A Nephropathy
S. Park¹, C. Baek², M. Yu³, Y. Kim¹, J. Moon¹, H. Go², Y. Kim², J. Lee⁴, S. Min¹, J. Ha¹, K. Moon¹, Y. Kim¹, C. Ahn¹, S. Park², H. Lee¹
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²Asan Medical Center, Seoul, Korea, Republic of, ³Hanyang University Hospital, Seoul, Korea, Republic of, ⁴Seoul National University Hospital, Boramae Medical Center, Seoul, Korea, Republic of
*Purpose: Although immunoglobulin A nephropathy (IgAN) is associated with a high risk of renal allograft failure, evidences for its treatment, including renin-angiotensin-aldosterone system blockade (RAASB)…
2019 American Transplant Congress
Near-Infrared Fluorescence Imaging with ZW800-1 Dye to Assess Donor Kidneys While on Ex-Vivo Normothermic Machine Perfusion
A. S. Arykbaeva¹, K. M. Rozenberg², M. L. Lo Faro², J. Hunter², J. B. Doppenberg¹, A. R. Valentijn³, A. G. Terwisscha van Scheltinga³, H. Putter⁴, I. P. Alwayn¹, J. V. Frangioni⁵, J. Burggraaf⁶, A. L. Vahrmeijer¹, R. J. Ploeg², V. A. Huurman¹
¹Department of Surgery, Leiden University Medical Center, Leiden, Netherlands, ²Nuffield Department of Surgical Sciences, Oxford, United Kingdom, ³Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, Netherlands, ⁴Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands, ⁵Curadel, LCC, Marlborough, MA, ⁶Centre for Human Drug Research, Leiden, Netherlands
*Purpose: At present, more older and higher risk donor kidneys are accepted resulting in increased uncertainty about quality. This may result in unjustified discard of…
2019 American Transplant Congress
Quantitative Epstein-Barr Virus Viral Load Monitoring in Pediatric Kidney Transplantation
C. Metran¹, M. E. Araujo¹, R. Cardoso¹, G. Araujo¹, T. De Paula¹, L. Cristofani², F. Penteado³, M. F. Pereira³, A. Watanabe¹
¹Pediatric Nephrology, ICr HC FMUSP, São Paulo, Brazil, ²Pediatric Oncology, ICr HC FMUSP, São Paulo, Brazil, ³Pediatric Infectology, ICr HC FMUSP, São Paulo, Brazil
*Purpose: Epstein Barr virus (EBV) belongs to the family of herpesvirus and is associated with a wide range of malignancies, including post-transplant lymphoproliferative disorder (PTLD).…