Articles tagged "Kidney"

2020 American Transplant Congress
The Role of CXCL16/CXCR6 in Mediating Macrophage Chemotaxis and M1 Macrophage Polarization in Murine Renal Ischemia Reperfusion Injury
W. Zhang¹, X. Zhang², G. Tu², C. Yang¹, G. Qi¹, M. Xu¹, T. Zhu¹
¹Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China, ²Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China
*Purpose: The objective of this study is to investigate the role of Chemokine (C-X-C motif) ligand 16 (CXCL16) and its unique receptor C-X-C chemokine receptor…
2020 American Transplant Congress
Conversion to a Belatacept Based Immunosuppression Regimen in Renal Transplant Recipients
K. Paplaczyk, K. Cunningham, C. D'Agostino, D. Pinelli, J. Schulte, A. Shetty
Northwestern Memorial Hospital, Chicago, IL
*Purpose: Belatacept, a co-stimulation blocker, is an alternative anti-rejection agent that may avoid nephrotoxic or intolerable adverse effects of calcineurin inhibitor (CNI) or mammalian target…
2020 American Transplant Congress
Genetic Testing of Living Related Donors for Inherited Renal Disease Improves Evaluation and Promotes Informed Choice of At-Risk Living Donors
C. P. Thomas¹, M. E. Freese¹, D. A. Katz²
¹Internal Medicine, University of Iowa, Iowa City, IA, ²Surgery, University of Iowa, Iowa City, IA
*Purpose: Living kidney donors (LKDs) with a family history of kidney disease are at higher risk of end-stage renal disease (ESRD) compared to LKDs without…
2020 American Transplant Congress
Mental Health of Unspecified Anonymous Living Kidney Donors after Donation
W. Zuidema¹, S. Ismail², J. Wetering van de¹, L. Raalten van², W. Weimar¹, E. Massey¹
¹Internal Medicine, Erasmus MC, Rotterdam, Netherlands, ²Psychiatry, Erasmus MC, Rotterdam, Netherlands
*Purpose: Aim: Anonymous living kidney donors donates to an unknown stranger. These donors undergo psychosocial assessment to minimize likelihood of psychological harm from donation. The…
2020 American Transplant Congress
Predicting Renal Graft Function Post Transplantation Using Clinical and Biological Features Supported by Machine Learning Algorithms
Y. Gao¹, Y. Cui¹, C. Kuscu², C. Kuscu², L. Gallon³, A. Bajwa², E. Akalin⁴, J. D. Eason², D. Maluf², V. Mas²
¹Department of Genetics, University of Tennessee Health Science Center, Memphis, TN, ²Dept of Surgery, Transplant Research Institute, James D. Eason Transplant Institute, University of Tennessee Health Science Center, Memphis, TN, ³Northwestern University, Chicago, IL, ⁴Albert Einstein Medical College, New York, NY
*Purpose: Predicting renal function post transplantation is a frequent challenge impacting physician decisions and patient quality of life. We aimed to develop a composite score…
2020 American Transplant Congress
Utilization of Kidneys with Microthrombi and Acute Kidney Injury
W. De Faria, E. Shipman, G. Ciancio, G. Guerra
Miami Transplant Institute, Miami, FL
*Purpose: Kidneys continue to be discarded for reasons such as surgical damage, high kidney donor profile index (KDPI), prolonged cold ischemia time, and acute kidney…
2020 American Transplant Congress
Ethical and Financial Consequences of Incidental Radiological Findings During Living Kidney Donor Evaluation
R. Mao, R. Kulkarni, C. Duran, H. Stevenson-Lerner, M. Mujtaba, J. Fair, M. Kueht
University of Texas Medical Branch, Galveston, TX
*Purpose: Living kidney donation (LKD) provides a unique situation in that diagnostic studies are ordered on a presumably healthy individual. Literature has shown that preoperative…
2020 American Transplant Congress
Use of Donor-Derived Cell-Free DNA Assay to Monitor Treatment Response to Allograft Rejection in Pediatric Renal Transplant Recipients
J. Steggerda¹, H. Phan Pizzo², J. Garrison², X. Zhang³, M. Haas⁴, I. Kim¹, S. Jordan¹, D. Puliyanda²
¹Comprehensive Transplant Center, Cedars Sinai Medical Center, West Hollywood, CA, ²Pediatric Nephrology, Cedars Sinai Medical Center, West Hollywood, CA, ³HLA Laboratory, Cedars-Sinai Med Center, West Hollywood, CA, ⁴Pathology, Cedars Sinai Medical Center, West Hollywood, CA
*Purpose: Acute rejection (AR) accounts for 13%-21% of graft failure in pediatrics (peds), with the number, severity, and response to treatment being a major determinant…
2020 American Transplant Congress
Clinicopathologic Features and Risk Factors of Proteinuria in Transplant Glomerulopathy: A Cross-Sectional Study
Q. Zhang¹, K. Budde¹, D. Schmidt¹, F. Halleck¹, M. Dürr¹, M. Naik¹, M. Mayrdorfer¹, W. Düttmann-Rehnolt¹, F. Klauschen², B. Rudolph², K. Wu²
¹Department of Nephrology, Charité – Universitätsmedizin Berlin, Berlin, Germany, ²Department of Pathology, Charité – Universitätsmedizin Berlin, Berlin, Germany
*Purpose: Proteinuria is common after transplantation. Transplant Glomerulopathy (TG), one of the main causes of post-transplant proteinuria, is also a major contributor to graft loss.…
2020 American Transplant Congress
Impact of Sarcopenia on Simultaneous Pancreas and Kidney Transplantation Outcomes: A Retrospective Observational Cohort Study
R. P. Meier, H. Noguchi, Y. Kelly, M. Sarwal, G. Conti, R. Halleluyan, M. Tavakol, P. Stock, C. Freise
Transplant Surgery, University of California San Francisco, San Francisco, CA
*Purpose: Sarcopenia has been identified as a recognized predictive variable for surgical outcomes. We hypothesized that sarcopenia could be a key measure to identify frail…