The Influence of the Donor Kidney Weight to Recipient Body Weight Ratio on Long-Term Renal Graft Outcomes
1Department of Transplantation Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, 2Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, 3Department of Nephrology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of
Meeting: 2020 American Transplant Congress
Abstract number: 349
Keywords: Graft failure, Kidney, Survival, Weight
Session Information
Session Name: Kidney Complications: Non-Immune Mediated Late Graft Failure
Session Type: Oral Abstract Session
Date: Saturday, May 30, 2020
Session Time: 3:15pm-4:45pm
Presentation Time: 3:27pm-3:39pm
Location: Virtual
*Purpose: To study the impact of the relative donor kidney size on long-term graft function and survival, we investigated the living donor renal transplants outcomes.
*Methods: We retrospectively assessed 1255 adult living donor kidney transplantation cases from January 2000 to December 2013 in Severance hospital. The chronological relationship between renal parameters and the kidney weight-to-recipient body weight (KW/BW) were analyzed.
*Results: Based upon KW/BW, the patients were divided into 4 groups, 1st quartile (KW/BW < 2.9; n=313), 2nd quartile (2.9≤KW/BW<3.5; n=314), 3rd quartile (3.5≤KW/BW<4.2; n=315), 4th quartile (4.2≤KWBW; n=313). The overall and death-censored graft survival at 10 years after transplantation were lower in 1st quartile group than others (p<0.05). The 1st quartile group showed lowest eGFR (p<0.05) at postoperative 1,6 months but the renal function of this group improved steadily, and after a year after surgery, the statistical difference was diminished compared to other groups. From 5 years after transplantation, the eGFR of 1st quartile group declined significantly lower than other groups (p<0.05) and this phenomenon sustained up to 10 years after operation.
*Conclusions: The KW/BW ratio is the independent determinant for long-term renal graft function and graft survival.
To cite this abstract in AMA style:
Yang S, Lee J, Jung Y, Kim B, Kim M, Kim S, Kim Y, Huh K. The Influence of the Donor Kidney Weight to Recipient Body Weight Ratio on Long-Term Renal Graft Outcomes [abstract]. Am J Transplant. 2020; 20 (suppl 3). https://atcmeetingabstracts.com/abstract/the-influence-of-the-donor-kidney-weight-to-recipient-body-weight-ratio-on-long-term-renal-graft-outcomes/. Accessed December 2, 2024.« Back to 2020 American Transplant Congress