2015 American Transplant Congress
DSA MFI Does Not Predict Late Antibody-Mediated Rejection Lesions Or Gene Expression Changes in Kidney Transplants
BACKGROUND: It is unclear whether donor-specific HLA antibody (DSA) levels at the time of a clinically-indicated biopsy can be predictive of the degree of antibody-mediated…2015 American Transplant Congress
Lack of Utilization of Pre-Emptive Transplantation in Those With Living Donor Kidney Transplants
Introduction: Time spent on dialysis before kidney transplantation (KTx) has been associated with worse outcomes. Pre-emptive transplants are not always possible due shortage of deceased…2015 American Transplant Congress
Evolution of Urinary Albumin Excretion in a Large Cohort of Kidney Donors: No Evidence of Progression
We have previously shown that the prevalence of albuminuria in donors is similar to age, gender and ethnicity matched NHANES controls. This cohort of 259…2015 American Transplant Congress
Combination of Clinical and Genetic Factors for Delayed Kidney Graft Function Prediction
In this study we sought to determine the risk for delayed graft function (DGF) in kidney transplants (Tx) with deceased donors (DD) through the analysis…2015 American Transplant Congress
Trajectory of Measured GFR Decades After Kidney Donation: Hyperfiltration Never Seems to End!
While the effect of uninephrectomy on loss of GFR is a cardinal issue for potential kidney donors, current information relies on surrogates of unknown validity,…2015 American Transplant Congress
Quality of Life, Financial, and Mental Health Outcomes for Individuals Turned Down for Live Kidney Donation
1UPenn, Philadelphia, PA; 2Harvard, Cambridge, MA.
Introduction: Individuals considering live kidney donation should have a thorough understanding of the risks and benefits. Regulations focus exclusively on donation risks. However, no data…2015 American Transplant Congress
Living Kidney Donation in the Elderly: The United Kingdom Experience
Introduction: The increasing demand for organs has led many institutions to accept elderly patients onto their living donor programmes. However no large UK based datasets…2015 American Transplant Congress
Effect of Living Kidney Donation on Glucose Metabolism and Insulin Resistance
The kidney contributes to glucose hemostasis through processes of insulin metabolism, gluconeogenesis, and glucose filtration. Little is known on insulin sensitivity in living kidney donors…2015 American Transplant Congress
Renal Tubular Dysfunction Following Donor Nephrectomy and Its Impact On Residual Kidney Function
Background: Recent publications have described an increasing incidence of end stage renal disease amongst kidney donors. This highlights the paucity of knowledge which exists in…2015 American Transplant Congress
Distinct Role of Complement Receptors C5L2 and C5aR in Acute Kidney Injury and Renal Fibrosis
ObjectiveAcute kidney injury (AKI) is a relevant complication in solid organ transplantation with incidence rates of ∼50-75 % after lung- and heart transplantation. In addition,…