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Articles tagged "Kidney"

  • 2015 American Transplant Congress

    Medication Non-Adherence in Those Waiting for a Transplant

    M. Wakefield,1 D. Murillo,2 C. Russell,3 C. Ashbaugh,1 S. Potts,2 L. Blakley,2 A. Deere.1

    1Department of Surgery, University of Missouri, Columbia, MO; 2Transplant Institute, Research Hospital, Kansas City, MO; 3School of Nursing and Health Studies, University of Missouri-Kansas City, Kansas City, MO.

    Purpose: Though poor medication adherence among adult kidney transplant patients is alarmingly high with distressing consequences, no one has systematically examined medication non-adherence in those…
  • 2015 American Transplant Congress

    Concerted T-Cell Activity Against Early and Late BKV-Antigens Is Necessary for Viral Clearance

    B. Weist,1,2 M. Schmueck,2 M. Dziubianau,2 P. Reinke,1,2 N. Babel.1,2

    1Department of Nephrology, Charite Universitaetsmedizin, Berlin, Germany; 2BCRT, Charite Universitaetsmedizin, Berlin, Germany.

    Polyomavirus-BK (BKV) associated nephropathy is a known cause of graft failure. No specific therapy is established so far and viral load monitoring accompanied by adjustment…
  • 2015 American Transplant Congress

    Pre-Liver Transplant Urinary Proteome Analysis Does Not Predict Development of Chronic Kidney Disease After Transplantation

    D. Milongo,1,3 J. Bascands,2,3,4 L. Esposito,1,3 L. Lavayssière,1,3 A. Del Bello,1,3 L. Rostaing,1,3,5 J. Schanstra,2,3,4 N. Kamar.1,3,5

    1Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France; 2Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France; 3Université Toulouse III Paul-Sabatier, Toulouse, France; 4Plateau de Protéomique des Liquides Biologiques, Institut of Cardiovascular and Metabolic Disease, Toulouse, France; 5INSERM U1043, IFR–BMT, Toulouse, France.

    Background and aims: Chronic kidney disease (CKD) is a common complication after liver transplantation. Kidney biopsies cannot be easily performed before liver transplantation to predict…
  • 2015 American Transplant Congress

    Recreational Marijuana Use Is Not Associated With Worse Kidney Allograft Outcomes

    G. Greenan, M. Anders, A. Leeser, J. Bromberg, S. Niederhaus.

    Department of Surgery, University of Maryland, Baltimore, MD; Department of Anesthesiology, University of Maryland, Baltimore, MD; Department of Surgery, University of Maryland, Baltimore, MD; Department of Surgery, University of Maryland, Baltimore, MD; Department of Surgery, University of Maryland, Baltimore, MD.

    Background: As marijuana (MJ) legalization is ongoing, kidney transplant programs need to develop listing criteria for MJ users. No data exist on whether recreational MJ…
  • 2015 American Transplant Congress

    Is Electron Microscopy Adding a Diagnostic Advantage in the Evaluation of Renal Allograft Biopsies for Antibody Mediated Rejection (AMR)?

    J. Papadimitriou, M. Chaudhry, C. Drachenberg, R. Ugarte, D. Klassen, E. Ramos, C. Cangro, B. Thomas, M. Mavanur, A. Haririan.

    Pathology and Medicine, University of Maryland School of Medicine, Baltimore, MD.

    Some electron microscopy (EM) findings have been consistently associated with antibody mediated microvascular injury; however, no large studies have been performed examining the concrete advantage…
  • 2015 American Transplant Congress

    APOL1 Risk Alleles in Live and Deceased Kidney Donors Are Associated With Shorter Renal Allograft Survival

    M. Doshi,1 M. Goggins,2 S. Norman,3 S. Ho,4 C. Winkler,5 J. Kopp.6

    1Medicine, Wayne State University, Detroit, MI; 2Medicine, Henry Ford Transplant Institute, Detroit, MI; 3Medicine, University of Michigan, Ann Arbor, MI; 4Gift of Life, Ann Arbor, MI; 5NCI, NIH, Bethesda, MD; 6NIDDK, NIH, Bethesda, MD.

    Kidneys from African American (AA) donors with two Apolipoprotein L1 (APOL1) risk alleles may be at higher risk of allograft loss after transplant. We sought…
  • 2015 American Transplant Congress

    Down-Regulation of Autophagy Correlates With Increased Apoptosis in the Kidney, But Not in the Liver, of Brain Dead Rats

    A. van Erp,1 R. Rebolledo,3 P. Ottens,1 J. Pirenne,2 H. Leuvenink,1 J.-P. Decuypere.2

    1Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; 2Department of Microbiology and Immunology, Catholic University Leuven, Leuven, Belgium; 3Department of Surgery, University of Chile, Santiago, Chile.

    Organs from brain dead donors have inferior quality and show higher rejection rates after transplantation compared to living donors. Brain death (BD) in the donor…
  • 2015 American Transplant Congress

    Infectious Complications With Plasmapheresis in Combination With Antithymocyte Globulin Compared to Antithymocyte Globulin Alone in the Treatment of Acute Rejection

    A. Leino, A. Hulbert, A. Delahunty, A. Rajab, J. Von Visger, H. Winters.

    The Comprehensive Transplant Center, The Ohio State University Wexner Medical Center, Columbus, OH.

    Background: Due to the complex nature of acute rejection (AR), multiple therapeutic modalities are necessary to prevent graft loss. The combination of prolonged cell depletion…
  • 2015 American Transplant Congress

    Characteristics and Outcomes of Kidneys Procured from Donors With KDPI > 80%

    M. Doshi, I. Hall, F. Weng, B. Schroppel, J. Ficek, R. Hasz, H. Thiessen-Philbrook, R. Formica, P. Reese, C. Parikh.

    TRIBE Consortium, New Haven, CT.

    Kidneys procured from donors with KDPI>80% are often biopsied and pumped, yet frequently discarded. The accuracy of these quality assessment tools remain controversial but contribute…
  • 2015 American Transplant Congress

    Outcomes of Kidney Transplantation of ABO- and Crossmatch-Incompatible Recipient-Donor Pairs Entered in Kidney Paired Donation Program

    D. Dadhania, M. Charlton, M. Aull, R. Friedlander, T. Muthukumar, J. Lee, M. Goris, D. Serur, S. Kapur, V. Sharma.

    Transplantation Medicine, Weill Cornell Medical Center, New York, NY.

    Kidney Paired Donation (KPD) enables ABO-incompatible (ABOI) and crossmatch-incompatible (XMI) patients to undergo transplantation using a 'more compatible' donor. Identification of factors that predict early…
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