Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Iguratimod Prevents Antibody-mediated Rejection by Regulating Germinal Center Formation and Antibody Production
H. Zhang, A. Chandraker, P. Sage, N. Murakami
Transplantation Research Center, Brigham and Women's Hospital, Boston, MA
*Purpose: Antibody-mediated rejection (ABMR) is a major cause of chronic renal allograft failure without effective treatment, and developing a novel therapy is an urgent need.…
2021 American Transplant Congress
Biomarkers of Kidney Injury and Repair in Expanded-Criteria Deceased Donor Kidney Transplant Recipients: A Prospective Study
A. Al Jurdi¹, O. Efe¹, B. Aoyama², M. Lima², H. Silva², I. Schmidt³, S. Waikar³, V. Sabbisetti⁴, L. V. Riella¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Charlestown, MA, ²Escola Paulista de Medicina, UNIFESP, São Paulo, Brazil, ³Boston Medical Center, Boston, MA, ⁴Brigham and Women’s Hospital, Boston, MA
*Purpose: Expanded-criteria donor (ECD) kidney transplants are at higher risk of kidney injury. Biomarkers that better predict short and long-term outcomes in ECD kidney transplant…
2021 American Transplant Congress
Does the Timing of Subclinical Acute Rejection After Kidney Transplant Matter?
P. Portocarrero¹, S. Park², K. Guo³, L. Zhao³, J. Friedewald²
¹Nephrology, Northwestern University, Chicago, IL, ²Transplant Nephrology, Northwestern University, Chicago, IL, ³Feinberg School of Medicine, Northwestern University, Chicago, IL
*Purpose: We hypothesized that the timing of subclinical acute rejection (subAR) diagnosed with biopsy, gene expression profile or donor-derived cell-free DNA is associated with poor…
2021 American Transplant Congress
Impact of Rejection in Pediatric and Young Adult Kidney Transplant Recipients on the Use of Mental Health Resources
E. Ruzicka¹, E. Lyons², C. Naclerio², A. Sikora², K. McKinnon², E. Blanchette², M. Chandran², M. Bock², E. Christofferson²
¹Children's Hospital Colorado, Aurora, CO, ²University of Colorado, Aurora, CO
*Purpose: Allograft rejection often results in increased hospital and medical resource utilization. Pediatric kidney transplant recipients (KTR) are at risk for psychosocial stressors, nonadherence to…
2021 American Transplant Congress
Seroprevalence of SARS-CoV-2 Antibodies in Transplant Recipients in a Croatian Transplant Center
A. Mrzljak¹, Z. Jurekovic¹, J. Pavicic Saric², L. Antolasic³, L. Milasincic³, I. Tabain³, T. Vilibic Cavlek³
¹Department of Internal Medicine, Merkur University Hospital, Zagreb, Croatia, ²Department of Anesthesiology, Merkur University Hospital, Zagreb, Croatia, ³Department of Microbiology, Croatian Institute of Public Health, Zagreb, Croatia
*Purpose: In Croatia, the first case of coronavirus disease (COVID-19) has been reported on 25 February 2020; however, the COVID-19 seroprevalence in the liver (LTR)…
2021 American Transplant Congress
Covid 19 Re-infection versus Re-activation in Two Renal Transplant Patients
L. Liriano-Ward, Y. Al Azzi, R. Bartash, C. Pynadath, M. Ajaimy, P. Loarte, J. Graham, S. Greenstein, M. Kinkhabwala, J. Rocca, E. Akalin
Montefiore Medical Center, New York, NY
*Purpose: Rare cases of potential COVID 19 re-infection have been reported throughout the world.*Methods: We describe two renal transplant recipients with possible SARS-COV-2 re-infection.*Results: Patient…
2021 American Transplant Congress
BKV-Associated Urothelial Carcinoma in Patients After Renal and Extrarenal Carcinoma
A. Schwarz¹, J. Schmitz², J. Gottlieb³, C. Bara⁴, H. Haller¹, J. Braesen²
¹Nephrology Department, Hannover Medical School, Hannover, Germany, ²Institute of Pathology, Hannover Medical School, Hannover, Germany, ³Department of Pneumology, Hannover Medical School, Hannover, Germany, ⁴Department of Thoracic Surgery, Hannover Medical School, Hannover, Germany
*Purpose: Polyomavirus BK (BKV) reactivation or transmission is a wellknown problem in renal transplant (TX) patients with BKV nephropathy and interstitial cystitis. The role of…
2021 American Transplant Congress
Long-Term Outcomes in Older Kidney Transplant Recipients from Older Donors
E. Cuadrado-Payán, E. Montagud-Marrahi, J. Casals-Urquiza, J. del Risco-Zevallos, D. Cucchiari, P. Ventura-Aguiar, I. Revuelta, G. Piñeiro, N. Esforzado, F. Cofan, J. Ugalde, J. Campistol, F. Oppenheimer, J. Torregrosa, F. Diekmann
Nephrology and Kidney Transplantation, Hospital Clínic de Barcelona, Barcelona, Spain
*Purpose: The age of patients referred for kidney transplantation has increased progressively. However, the precise influence of age on hard outcomes after transplantation is controversial*Methods:…
2021 American Transplant Congress
Poor Reliability of Karnofsky Performance Score in Kidney Transplant Candidates
M. R. Stedman, D. J. Watford, G. M. Chertow, J. C. Tan
Medicine, Stanford University, Palo Alto, CA
*Purpose: The Karnofsky Performance Status (KPS) Scale has been used as a proxy for frailty and as a predictor of transplant outcomes, however reliability of…
2021 American Transplant Congress
Patients’ Perceptions of Kidney Transplant Failure and Transitioning to Dialysis
E. Ramos¹, C. Gu², C. Hanson², K. Abdel-Kader³, K. Bonnet², D. Schlundt², E. Gordon⁴, B. P. Concepcion³
¹Cleveland Clinic Foundation, Cleveland, OH, ²Vanderbilt University, Nashville, TN, ³Vanderbilt University Medical Center, Nashville, TN, ⁴Northwestern University, Chicago, IL
*Purpose: Approximately 5,000 US kidney transplant recipients return to dialysis each year due to allograft failure. Understanding how kidney allograft failure and transitioning to chronic…