2021 American Transplant Congress
The Impact of 4-weeks of Supervised Exercise on Frailty and Lower Extremity (LE) Function in Patients with Advanced Chronic Kidney Disease (CKD)
*Purpose: Although frailty is a modifiable risk factor for morbidity and mortality among kidney transplant (KT) candidates, the optimal duration of effective prehabilitation interventions is…2021 American Transplant Congress
Development and Validation of a Novel Peripheral Blood Based Gene Signature for Acute Rejection Following Renal Transplantation
Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
*Purpose: The aim of this study is to utilize advanced machine learning methods to construct a peripheral blood-based gene signature for acute rejection following kidney…2021 American Transplant Congress
De-novo Use Comparison Between Extended-release Once-daily Tacrolimus (Envarsus Xr®) and Immediate-release Twice-daily Tacrolimus (Prograf®) – A Single Center’s Experience
*Purpose: Envarsus XR® is approved for de-novo use post-kidney transplantation at a higher starting dose (0.14mg/kg/day) as compared with Prograf® (0.1 mg/kg/day) despite better bioavailability.…2021 American Transplant Congress
Higher Number of Tacrolimus Dose Adjustments and Trough Level Measurements in Kidney Transplant Recipients with CYP3A5*1 Alleles
*Purpose: Tacrolimus (TAC) metabolism is dependent on the functional status of the cytochrome P450 family enzyme CYP3A5 which has three common loss of function (LoF)…2021 American Transplant Congress
Belatacept Exposure Not Associated With Rejection. Can Doses be Lowered without Compromising Efficacy?
*Purpose: Phase 1 and 2 belatacept(BELA) pharmacokinetic(PK) studies informed dosing in phase 3 studies. PK data from these studies revealed higher BELA troughs on Day…2021 American Transplant Congress
Impact of a Latinx Kidney Transplant Clinic
Abdominal Transplant Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC
*Purpose: To evaluate the impact of a Latinx clinic in our institution. With a growing increase of end stage renal disease (ESRD)in the Latino population…2021 American Transplant Congress
Novel Mixed Lymphocyte Reaction Monitoring System That Predicts Chronic Antibody- Mediated Rejection in Kidney Transplant Recipients
*Purpose: Chronic active antibody-mediated rejection (CAAMR) induced by de novo donor-specific antibodies (DSA) is the main cause of graft loss in the long-term. Currently, there…2021 American Transplant Congress
Outcomes of Kidney Transplantation from Hepatitis C Virus (HCV) Infected Donors Stratified by Recipient HCV Serostatus: A Mate Kidney Analysis
*Purpose: Kidneys from donors infected with hepatitis C virus (HCV) are increasingly used for transplantation into HCV positive (+) recipients historically and into HCV negative…2021 American Transplant Congress
Prevalence of Hepatitis E Virus Infection in Solid Organ Transplant Recipients: A Systematic Review and Meta-analysis
*Purpose: Hepatitis E virus (HEV) infection is an underdiagnosed disease due to the use of serological assays with low sensitivity. Although most patients with HEV…2021 American Transplant Congress
Iguratimod Prevents Antibody-mediated Rejection by Regulating Germinal Center Formation and Antibody Production
Transplantation Research Center, Brigham and Women's Hospital, Boston, MA
*Purpose: Antibody-mediated rejection (ABMR) is a major cause of chronic renal allograft failure without effective treatment, and developing a novel therapy is an urgent need.…
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