ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2021 American Transplant Congress

    Intensive Blood Pressure Control Preserves Kidney Allograft Function

    K. A. Agarwal1, U. K. Agarwal2, G. S. Silva3, K. J. Pollick3, M. Pavlakis1

    1Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA, 2Biostatistics consultant, Boston, MA, 3Beth Israel Deaconess Medical Center, Boston, MA

    *Purpose: Kidney transplant recipients (KTRs) are at higher risk of major adverse cardiovascular events compared to the general population, with HTN being a crucial risk…
  • 2021 American Transplant Congress

    Clinical and Molecular Profiling Can Help in Predicting the Response to Alemtuzumab Treatment in Kidney Transplant Recipients with Severe or Glucocorticoid-Resistant Acute Rejection

    D. M. Peelen1, M. van der Zwan1, M. C. Clahsen-van Groningen2, D. A. Mustafa2, C. C. Baan1, D. A. Hesselink1

    1Internal Medicine - Nephrology & Transplantation, Erasmus MC, Rotterdam, Netherlands, 2Pathology, Erasmus MC, Rotterdam, Netherlands

    *Purpose: Alemtuzumab is an effective drug for the treatment of severe or glucocorticoid-resistant acute kidney allograft rejection (AR), but can also cause severe adverse events.…
  • 2021 American Transplant Congress

    Impact of High-Risk EBV Discordance Status on Survival Outcomes in Kidney Transplant Recipients: A Multivariable Analysis

    A. Dinesh1, S. Jackson2, T. L. Pruett1, S. Riad3

    1Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN, 2Biostatistics, Analytics Consulting Services- Solid Organ Transplant, M Health Fairview, Minneapolis, MN, 3Department of Medicine, University of Minnesota, Minneapolis, MN

    *Purpose: High-risk EBV discordance has been linked to Post-Transplant Lymphoproliferative Disorder (PTLD) after kidney transplantation; however, the impact on recipient and graft survival is under-reported.…
  • 2021 American Transplant Congress

    Effect of Multi-Organ Transplant Allocation on Pediatric Kidney Waitlist Candidates

    D. Shepherd, R. M. Engen

    Pediatric Nephrology, Ann & Robert H. Lurie Children's Hospital, Chicago, IL

    *Purpose: Multi-Organ Transplants (MOTs) have variable allocation policies and often take precedence over other waitlist candidates. Lack of defined MOT guidelines divert kidneys to MOT…
  • 2021 American Transplant Congress

    Development of Diagnosis Method of Acute Graft Rejection After Kidney Transplantation Using Metabolome Analysis by Liquid Biopsy Approach

    H. Iwamoto1, M. Sugimoto2, O. Konno1, I. Akashi3, M. Okihara1, Y. Kihara1, T. Ueno1

    1Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan, 2Research and Development Center for Minimally Invasive and Preemptive Medicine, Institute of Medi, Tokyo Medical University, Tokyo, Japan, 3Kidney transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan

    *Purpose: Presently, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy procedure…
  • 2021 American Transplant Congress

    Atg16l-Dependent Autophagy Attenuates Procession of Renal Interstitial Fibrosis in Chronic Renal Graft Dysfunction via Regulating Tumor Necrosis Factor Alpha (tnf-α) Induced Endmt

    Z. Gui, Z. Wang, Z. Han, J. Tao, X. Ju, R. Tan, M. Gu

    The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    *Purpose: Chronic renal graft dysfunction is characterized by inflammation, tubular injury, and interstitial fibrosis. We have confirmed that endothelial-mesenchymal transition (EndMT) was one of important…
  • 2021 American Transplant Congress

    The Relationship Between Health Literacy and Adverse Outcomes After Kidney Transplantation

    E. Lorenz, T. Petterson, C. Schinstock, W. Sanchez, K. Yost

    Mayo Clinic, Rochester, MN

    *Purpose: Limited health literacy has been associated with a decreased likelihood of listing for transplant and an increased risk of waitlist mortality among kidney transplant…
  • 2021 American Transplant Congress

    Pilot Study for the Use of Shortened Preemptive Therapy with Glecaprevir/pibrentasvir (g/p) and Ezetimibe in Hepatitis C Seronegative Solid Organ Transplant Recipients (Kidney and Heart) of Hepatitis C Viremic Donors

    B. Aqel1, H. Khamash2, A. Moss3, D. E. Steidley4, R. C. Dickson1

    1Gastroenterology and Hepatology, Mayo Clinic, Phoenix, AZ, 2Nephrology and Hypertension, Mayo Clinic, Phoenix, AZ, 3Transplant Surgery, Mayo Clinic, Phoenix, AZ, 4Cardiology, Mayo Clinic, Phoenix, AZ

    *Purpose: This prospective study aims to assess the efficacy of preemptive therapy with eight days of a combination of direct-acting antivirals (DAAs) (Mavyret) (Pibrentasvir /Glecaprevir)…
  • 2021 American Transplant Congress

    Video Virtual Transplant Evaluation and Listing

    V. Casingal1, B. Thrasher2, J. Brown2, C. Fotiadis2

    1Department of Surgery, Atrium Health, Charlotte, NC, 2Department of Transplant, Atrium Health, Charlotte, NC

    *Purpose: Due to the COVID-19 pandemic, many hospitals suspended in person evaluations of kidney transplants during the March-April time period of 2020. State and local…
  • 2021 American Transplant Congress

    Donor Kidney-Resident Macrophages Promote Allograft Inflammation and CD8 T Cell Response Post-Transplantation

    A. Dangi1, S. Yu2, I. Husain1, R. Geesala1, X. Luo1

    1Nephrology, Medicine, Duke University, Durham, NC, 2Division of Organ Transplantation, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    *Purpose: Kidney-resident macrophages play important roles in maintaining normal kidney function and promoting prompt repair following kidney injuries. Nevertheless, their fate and role in kidney…
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