Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Environmental Factors That Shape T-cell Alloimmunity: Role of the Microbiome
K. Janek¹, J. H. Fechner¹, R. A. Daley¹, K. Krautkamer¹, F. Rey², J. D. Mezrich¹
¹Surgery, University of Wisconsin School of Medicine & Public Health, Madison, WI, ²Bacteriology, University of Wisconsin, Madison, WI
*Purpose: Unlike other types of immunity, T-cell alloimmune responses to mismatched MHC proteins do not need priming by a previous exposure. While genetic differences between…
2021 American Transplant Congress
Identification and Comprehensive Validation of Prognostic Genes After Ischemic and Reperfusion Injury Across Different Donor Types in Renal Transplantation
D. Zhang, Y. Wang, Y. Wang, X. Hu
Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
*Purpose: Ischemic and reperfusion injury (IRI) remains an inevitable and major challenge for renal transplant patients. The current study aims to obtain overall insights into…
2021 American Transplant Congress
Donor-Derived Cell-Free DNA Performance Characteristics are Similar for Repeat and Primary Kidney Transplant Recipients
V. R. Peddi¹, S. Akkina², S. C. Jordan³, W. Tian⁴, Y. Qazi⁵
¹California Pacific Medical Center, San Francisco, CA, ²Loyola University Medical Center, Maywood, IL, ³Cedars-Sinai Medical Center, Los Angeles, CA, ⁴CareDx, Brisbane, CA, ⁵University of Southern California, Los Angeles, CA
*Purpose: Repeat kidney transplants (RKT) represent 12.4% of kidney transplants (KT) (10.9% of all living donor and 13.6% of all deceased donor). Most RKT are…
2021 American Transplant Congress
Long-Term Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Living Donor Renal Transplant Recipients
J. Leventhal¹, J. Galvin², J. Mathew¹, L. Gallon¹, D. Belshe¹, M. Gibson¹, K. Ravindra³, M. Horwitz³, S. Ildstad⁴
¹Northwestern University, Comprehensive Transplant Center, Chicago, IL, ²Northwestern University, Chicago, IL, ³Duke Medical Center, Durham, NC, ⁴University of Louisville, Llouisville, KY
*Purpose: 37 subjects were transplanted in a phase 2 protocol based upon tolerogenic CD8+/TCR-facilitating cells (FCR001) to induce tolerance in recipients of living donor renal…
2021 American Transplant Congress
COVID-19 in Hospitalized Kidney Transplant Recipients: Clinical Course, Prognostic Factors and Differences Between First and Second Waves
N. Macías, M. Rodríguez Ferrero, A. Acosta, J. Carbayo, Á. González Rojas, A. Muñoz de Morales, A. García Prieto, M. Goicoechea
Nephrology, Hospital Gregorio Marañón, Madrid, Spain
*Purpose: The aim was to describe the clinical course and management of SARS-CoV-2 infection in kidney transplant recipients (KTR) hospitalized with COVID-19, identify risk factors…
2021 American Transplant Congress
Outcomes of Kidney Transplantation at the Epicenter of the Covid-19 Pandemic: The Experience of the Ospedale Maggiore Policlinico
E. Favi¹, C. Alfieri², M. Gandolfo², A. Brescacin¹, M. Bilato³, R. Cacciola⁴, P. Messa², M. Ferraresso⁵
¹Renal Transplantation, Ospedale Maggiore Policlinico, Milan, Italy, ²Nephrology, Ospedale Maggiore Policlinico, Milan, Italy, ³Urology, Ospedale Maggiore Policlinico, Milan, Italy, ⁴HBP Surgery, Policlinico Tor Vergata, Rome, Italy, ⁵Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
*Purpose: To evaluate patient- and allograft-related outcomes following living and deceased donor kidney transplantation (KTx) in a unit operating at the epicentrum of the COVID-19…
2021 American Transplant Congress
Influence of HLA Compatibility on Bk Virus Associated Nephropathy Among Japanese Living Donor Kidney Transplant Recipients
N. Fujiyama¹, M. Saito², R. Yamamoto², R. Sagehashi², T. Saito², S. Kashima², K. Numakura², S. Narita², T. Habuchi², S. Satoh¹
¹Center for Kidney Disease and Transplantaion, Akita University Hospital, Akita, Japan, ²Department of Urology, Akita University Graduate School of Medicine, Akita, Japan
*Purpose: BK polyomavirus-associated nephropathy (BKVN) after kidney transplantation is associated with a high morbidity and higher risk of graft loss. In this study, the relationship…
2021 American Transplant Congress
Simulation Model for Cytomegalovirus Matching in Deceased Donor Kidney Allocation System in the U.S.
B. Tanriover¹, V. K. Ariyamuthu¹, T. Zangeneh², M. M. Al Obaidi², Y. Ulukus³, M. A. Ergun³, B. Sandikci⁴
¹Department of Medicine / Nephrology, University of Arizona, COM Tucson, Tucson, AZ, ²Department of Medicine / Infectious Disease, University of Arizona, COM Tucson, Tucson, AZ, ³Operations Management, Istanbul Technical University, Istanbul, Turkey, ⁴Operations Management, University of Chicago, Chicago, IL
*Purpose: The prevalence of positive and negative cytomegalovirus (CMV) serology among transplant recipients and donors are approximately 60-65% and 30-35%, respectively. CMV mismatch, donor-positive/recipient-negative status…
2021 American Transplant Congress
A Kidney Waitlist Outcomes Timeline to Visualize Candidate Offers and Outcomes
C. Schaffhausen¹, J. Miller², A. Matas³, A. Israni⁴, A. Wey⁵, A. Hart⁴
¹Hennepin Healthcare Research Institute / University of Minnesota (UMN), Minneapolis, MN, ²Chronic Disease Research Group, Minneapolis, MN, ³Department of Surgery, UMN, Minneapolis, MN, ⁴Hennepin Healthcare / UMN, Minneapolis, MN, ⁵Scientific Registry of Transplant Recipients, Minneapolis, MN
*Purpose: While transplant centers closely monitor posttransplant outcomes for each transplant recipient, centers currently lack data to monitor waitlist outcomes of individual candidates. Candidates who…
2021 American Transplant Congress
Intersecting Disparities in Health Literacy Among Renal Patients Experiencing Transplant Barriers
C. W. Nonterah, K. Workman, S. Shah
Psychology, University of Richmond, Richmond, VA
*Purpose: Recent data from the United States Renal Data System (USRDS, 2020) indicate that 131, 636 patients were diagnosed with end-stage renal disease (ESRD) in…