Articles tagged "Kidney transplantation"

2015 American Transplant Congress
Histological Analysis in ABO-Compatible and Incompatible Kidney Transplantation By Performing 3-Month and 1-Year Protocol Biopsies
K. Masutani,¹ A. Tsuchimoto,¹ Y. Matsukuma,¹ K. Kurihara,² Y. Okabe,² H. Kitada,² M. Tanaka,² T. Kitazono,¹ K. Tsuruya.¹
¹Department of Medicine and Clinical Science, Kyushu University, Fukuoka, Japan; ²Department of Surgery and Oncology, Kyushu University, Fukuoka, Japan.
Background. ABO incompatible kidney transplantation (ABO-I KTx) is nowadays a well-established procedure to expand living donor source. Graft and patient survivals of ABO-I KTx were…
2015 American Transplant Congress
Early Relapse of Atypical HUS Following ABO Incompatible Living Related Paediatric Renal Re-Transplant Successfully Treated With Eculizumab
J. Stojanovic,¹ A. Adamusiak,² N. Sebire,³ S. Marks,¹ N. Mamode.²
¹Department of Paediatric Nephrology, Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom; ²Department of Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; ³Department of Histopathology, Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom.
Background. The female patient presented at 3 years of age with clinical features suggestive of aHUS confirmed genetically as complement factor I mutation (heterozygous for…
2015 American Transplant Congress
Safety and Efficacy of Pegylated Interferon and Ribavirin for Chronic Hepatitis C Following Renal Transplantation
G. Chen, L. Zhu, S. Chen, X. Wang, Z. Lin.
Institute of Organ Transplantation, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Objective We sought to investigate the safety and efficacy of pegylated Interferon (PEG-IFN) and ribavirin for chronic hepatitis C (HCV) following renal transplantation.Methods Ten adult…
2015 American Transplant Congress
Immune Reconstitution in Recipients of Living Donor Kidney/Hematopoietic Stem + Facilitating Cell Transplants
J. Leventhal,¹ M. Elliott,² E. Yolcu,² L. Bozulic,³ D. Tollerud,³ J. Mathew,¹ I. Konieczna,¹ M. Ison,¹ M. Badder,³ M. Abecassis,¹ J. Miller,¹ L. Gallon,¹ S. Ildstad.³
¹Comprehensive Transplant Center, Northwestern Memorial Hospital, Chicago, IL; ²University of Louisville, Institute for Cellular Therapeutics, Louisville, KY; ³Regenerex, LLC, Louisville, KY.
We report the long-term results from a reduced-intensity nonmyeloablative conditioning approach to establish high levels of donor chimerism without graft-versus-host disease (GVHD) in mismatched related…
2015 American Transplant Congress
Renal Outcomes of Cross Match Positive Simultaneous Liver Kidney (SLK) Transplant Recipients Compared to Cross Match Positive Kidney Allograft Recipients
S. Vaishnav,¹ T. Taber,¹ W. Goggins,² S. Nagaraju,² J. Fridell,² A. Sharfuddin,¹ M. Yaqub,¹ D. Mishler,¹ M. Mujtaba.¹
¹IUSM, IU Health, Indianapolis, IN; ²Surgery, Transplant, Indiana University School of Medicine, Indianapolis, IN.
The protective role of liver in cross-match(XM) positive SLK recipients and its impact on the incidence of renal antibody mediated rejection (AMR) is unclear.A retrospective…
2015 American Transplant Congress
Is Pretransplant Anti-A/B Antibody Removal Prerequisite for Successful ABO Incompatible Kidney Transplantation in Children?
S. Shishido,¹ T. Kawamura,¹ Y. Hamasaki,² Y. Takahashi,¹ Y. Hyodo,¹ Y. Itabashi,¹ H. Nihei,¹ T. Yonekura,¹ Y. Inaba,² Y. Yoshida,² K. Sakai,¹ A. Aikawa.¹
¹Nephrology, Toho University, School of Medicine, Tokyo, Japan; ²Pediatric Nephrology, Too University, School of Medicine, Tokyo, Japan.
Purpose: We have recently demonstrated that the long-term outcome of ABO incompatible living donor kidney transplantation (ABOiKT) in children was comparable to those of ABO…
2015 American Transplant Congress
Predicting Graft Loss in a Population of Kidney Transplant Patients Diagnosed With ABMR/TG
J. Reeve,¹ P. Halloran.¹
¹Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada; ²Medicine, University of Alberta, Edmonton, AB, Canada.
ABMR is the main cause of late graft loss in kidney transplants. Our goal was to determine the variables most strongly predictive of graft loss…
2015 American Transplant Congress
Impact of Community Risk on Early Hospital Readmission Following Kidney Transplant
E. King,¹ L. Kucirka,¹ M. McAdams-DeMarco,^1,2 A. Massie,^1,2 J. Schold,³ D. Segev.^1,2
¹Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD; ²Epidemiology, Johns Hopkins University, School of Public Health, Baltimore, MD; ³Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.
Background: Early hospital readmission (EHR) is associated with increased morbidity, mortality, and cost in kidney transplantation (KT). Community risk may be associated with EHR above…
2015 American Transplant Congress
Six Year Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Mismatched Living Donor Renal Transplant Recipients
J. Leventhal, M. Abecassis, L. Gallon, J. Galvin, J. Mehta, K. Ravindra, D. Tollerud, M. Elliott, S. Ildstad.
Comprehensive Transplant Center, Northwestern Memorial Hospital, Chicago, IL; Duke University, Durham, NC; Institute for Cellular Therapeutics, University of Louisville, Louisville, KY; Regenerex, LLC, Louisville, KY.
27 subjects have been transplanted in a phase 2 protocol (IDE 13947) based upon tolerogenic CD8+/TCR- facilitating cells (FCRx) and 200 cGy TBI-based nonmyeloablative conditioning…
2015 American Transplant Congress
Everolimus Versus Mycophenolate for Recipients of Kidney Transplants from Expanded Criteria Donors (ECD) Receiving Anti-Thymocyte Globulin and Tacrolimus
H. Tedesco-Silva,¹ C. Felipe,¹ A. Ferreira,¹ M. Cristelli,¹ A. Bessa,¹ P. Ueno,¹ T. Sandes- Freitas,¹ G. Bassos,¹ W. Aguiar,² H. Proença,³ J. Medina-Pestana.¹
¹Nephrology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; ²Urology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; ³Pathology, UNIFESP, Sao Paulo, Brazil.
Introduction: Recipients of kidneys recovered from expanded criteria donors are at higher risk to develop delayed graft function (DGF) and acute rejection (AR), leading to…