ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    Impact of Educational Attainment On Kidney Transplant Outcomes By Race

    A. Aguirre-Alarcon,1 P. Friedmann,1 A. Gregg,2 L. Kayler.3

    1Albert Einstein College of Medicine, Bronx, NY; 2University of Florida, Gainesville, FL; 3Department of Surgery, Montefiore Medical Center, Bronx, NY.

    Educational attainment is associated with disparities in graft and recipient survival in kidney transplant (KTX) candidates; however, the impact of educational status within racial groups…
  • 2015 American Transplant Congress

    Correlation Between Level of Biomarkers Measured in Perfusate of Machine-Preserved ECD/DCD Kidneys and Post-Transplant Graft Function

    E. Ablorsu,1 S. Zouwail,2 P. Laftsidis,1 B. Cook,1 L. Szabo.1

    1Cardiff Transplant Unit, University Hospital for Wales, Cardiff, United Kingdom; 2The Medical Biochemistry and Immunology Department, University Hospital for Wales, Cardiff, United Kingdom.

    Background:DCD and ECD kidneys are associated with higher risk of failure compare to SCD kidneys. Therefore we see increasing need to identify sensitive tool to…
  • 2015 American Transplant Congress

    Comparison of Efficacy and Renal Function in KidneyTransplant Recipients Receiving Tacrolimus (TAC)-Based Immunosuppressive Regimens in Combination With Everolimus (EVR) or Mycophenolate (MPA)

    A. Ferreira,1 C. Felipe,1 P. Ueno,1 P. Hannun,1 P. Ruppel,1 T. Sandes-Freitas,1 H. Proença,3 J. Medina- Pestana,1 H. Tedesco-Silva.1

    1Nephrology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 2Pathology, UNIFESP, Sao Paulo, Brazil.

    Introduction: Acute rejection and renal function are associated with long-term renal allograft survival. We evaluated these outcomes in patients receiving reduced TAC exposure combined with…
  • 2015 American Transplant Congress

    mTOR-Based CNI Minimization Vs Withdrawal in African American Kidney Transplant Recipients

    J. Fleming,1 D. Taber,2 N. Pilch,1 H. Meadows,1 C. Mardis,1 J. McGillicuddy,2 S. Nadig,2 K. Chavin,2 P. Baliga,2 C. Bratton.2

    1Pharmacy, Medical University of South Carolina, Charleston, SC; 2Surgery, Medical University of South Carolina, Charleston, SC.

    The purpose of this study was to compare mTOR-based CNI withdrawal vs. minimization in African American (AA) kidney transplant (KTx) recipients.METHODS: This was a single-center,…
  • 2015 American Transplant Congress

    Reassessing Tubulitis and Interstitial Infiltrate: Creating a New Probabilistic Definition of TCMR

    P. Halloran, I. Salazar, M. Lopez, J. Chang.

    Alberta Transplant Applied Genomics Centre, Edmonton, Canada.

    Conventional diagnosis of T cell-mediated rejection (TCMR) in kidney transplant biopsies relies on interstitial inflammation (i-lesions), tubulitis (t-lesions), vasculitis (v-lesions) and experience-derived interpretation rules. The…
  • 2015 American Transplant Congress

    The Effects of Dialysis Vintage and Hypertensive Renal Failure on Colonoscopy Findings During Kidney Transplant Evaluation

    Y. Zheng,1 K. Chaung,1 P. Park,1 J. Augustine,2 N. Sarabu,2 J. Schulak,2 E. Sanchez,2 V. Humphreville,2 J. Ammori,2 K. Woodside.2

    1School of Medicine, Case Western Reserve University, Cleveland, OH; 2Department of Surgery, University Hospitals Case Medical Center, Cleveland, OH.

    Colonoscopy as a screening modality starting at age 50 has recently undergone scrutiny due to concerns over the risks and benefits. We sought to identify…
  • 2015 American Transplant Congress

    HLA-Cw Mismatches Are Not Associated With Worse Graft Outcomes After Kidney Transplantation Even in High Levels of Antigen Expression

    M. Askar,1 N. Elfadawy,1,2 S. Flechner,1 K. Abu-Elmagd,1 J. Fung,1 J. Schold.1

    1Cleveland Clinic, Cleveland; 2University of Alexandria, Alexandria, Egypt.

    The HLA-Cw antigens are distinct in having relatively lower expression on the cell surface compared to the other HLA class I loci. Higher HLA Cw…
  • 2015 American Transplant Congress

    No Significant Outcome Benefit for Brand-Name Versus Generic Tacrolimus in Kidney Transplant Recipients: SRTR Analysis

    D. Goldfarb,1 E. Poggio,1 S. Flechner,1 R. Fatica,1 J. Schold.2

    1Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH; 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.

    IntroGeneric formulations of tacrolimus have been available for maintenance immunosuppression since 2009. Our aim was to evaluate the frequency of use of generic tacrolimus and…
  • 2015 American Transplant Congress

    Long-Term Efficacy and Safety of an EVR- Vs. an MMF-Based Regimen After Pediatric Kidney Transplantation (KTX): A Case-Control Study Within the CERTAIN Registry

    L. Pape,1 T. Ahlenstiel-Grunow,1 B. Hoecker,2 M. Bald,3 K. Kruppka,2 B. Toenshoff,2 L. Brunkhorst.1

    1Pediatric Nephrology, Hannover Medical School, Hannover, NDS, Germany; 2Pediatric Nephrology, University Children's Hospital, Heidelberg, BW, Germany; 3Pediatric Nephrology, Olgahospital, Stuttgart, BW, Germany.

    Background: Only short-term trials using everolimus (EVR) in children after KTX have been published. Hereby we present 4 year data on low-dose ciclosporin A (CsA),…
  • 2015 American Transplant Congress

    Intra-Renal Cytokine Measurement Detected During Kidney Allograft Biopsies Portend Severity of Histological Injury

    N. Leca, S. Anderson, K. Muczynski.

    Division of Nephrology, University of Washington, Seattle, WA.

    Histological changes observed on renal allograft biopsies, although considered the current standard for evaluation of allograft injury, lack specificity and disease activity assessment. We devised…
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