Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Potential Kidney Donors with Asymptomatic Micorsocpic Hematuria: Histopathological Findings & Outcomes.
E. Hassan,^1,2 H. Aleid,¹ T. Zulfiquar,¹ I. Ibrahim,^1,3 H. Almana.⁴
¹Department of Kidney & Pancreas Transplantation, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia; ²Department of Nephrology, Fayoum University, Fayoum, Egypt; ³Department of Nephrology, Cairo University, Cairo, Egypt; ⁴Department of Anatomic Pathology, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
Background: Microscopic hematuria is not uncommon in potential kidney donors. After excluding urological causes, most of these donors require kidney biopsy to exclude glomerular lesions.…
2016 American Transplant Congress
Elevated Intragraft Expression of Innate Immunity and Cell Death-Related Markers Characterizes Deceased Donor Conditions and Is a Risk Factor for Adverse Graft Outcome.
M. Eikmans,¹ J. Yang,¹ G. Haasnoot,¹ C. van Kooten,² M. Mallat,² H. de Fijter,² I. Bajema,³ F. Claas.¹
¹Immunohematology, LUMC, Leiden, Netherlands; ²Nephrology, LUMC, Leiden, Netherlands; ³Pathology, LUMC, Leiden, Netherlands.
Background: The innate immune response is increasingly being recognized in allograft injury after kidney transplantation. We aimed to establish the relationship of innate immune gene…
2016 American Transplant Congress
The Relationship Between Kidney Donor Profile Index and Six Month eGFR in Deceased Donor Recipients.
D. Keith, A. Nishio Lucar, G. Vranic.
Division of Nephrology, University of Virginia, Charlottesville, VA.
Kidney function, as measured by GFR, at 6 months post-kidney transplant is a powerful predictor of long-term post-transplant outcomes. This study sought to understand the…
2016 American Transplant Congress
Complications of Dual Antiplatelet Therapy Among Recipients of Kidney Transplants.
F. Weng, A. Athavale, K. Hussain, K. Tibaldi, G. Rogal.
Saint Barnabas Medical Center, Livingston, NJ.
Introduction: For patients undergoing percutanous coronary intervention (PCI) with drug-eluting stents, dual antiplatelet therapy (DAPT) is often used to prevent stent thrombosis. Kidney transplantation of…
2016 American Transplant Congress
Kidney Allotransplantation Induces the Differentiation of Antigen-Experienced CD8 T Cells with Enhanced Metabolic Profiles.
G. Tilly,^1,2 M. Yap,^1,2 M. Giral,^1,2,3 S. Brouard,^1,3 C. Pecqueur,⁴ N. Degauque.^1,3
¹UMR 1064, INSERM, Nantes, France; ²Université de Nantes, Nantes, France; ³ITUN, CHU de Nantes, Nantes, France; ⁴UMR 892, INSERM, Nantes, France.
Background. Naïve and memory CD8 T cells have been shown to exhibit different metabolic profiles, especially upon antigen stimulation. However, it is unknown whether the…
2016 American Transplant Congress
Clinical Outcome of Elderly Living Kidney Donors: A Single-Center Study in Japan.
J. Hasegawa, K. Unagami, M. Okumi, K. Omoto, M. Inui, H. Ishida, K. Tanabe.
Urology, Tokyo Women's Medical University, Tokyo, Japan.
Background: Previous studies and current guidelines have suggested that elderly persons can be living kidney donors; however, reports on elderly donors >70 years old are…
2016 American Transplant Congress
Acute Rejection Profoundly Impacts Graft Survival in Young but Not in Old Kidney Transplant Recipients.
C. Denecke,^1,3 M. Biebl,^1,3 J. Fritz,² A. Brandl,^1,4 S. Weiss,^1,4 T. Dziodzio,^1,3 F. Aigner,^1,3 R. Sucher,^1,3 C. Bösmüller,¹ J. Pratschke,^1,3,4 R. Öllinger.^1,3
¹Visceral, Transplantation and Thoracic Surgery, Medical University, Innsbruck, Austria; ²Medical Statistics, Informatics and Health Economics, Medical University, Innsbruck, Austria; ³General, Visceral and Transplantation Surgery, Charité Universitätsmedizin, Campus Virchow, Berlin, Germany; ⁴General, Visceral, Vascular and Thoracic Surgery, Charite Universitätsmedizin, Campus Mitte, Berlin, Germany.
Background: The proportion of marginal grafts and elderly recipients awaiting kidney transplantation is ever increasing. The correlation of age with DGF and acute rejection determines…
2016 American Transplant Congress
Eculizumab for Chronic Antibody-Mediated Injury in Kidney Transplant Recipients: A Randomized-Controlled Trial.
S. Kulkarni,¹ N. Kirkiles-Smith,² Y. Deng,³ R. Formica,⁴ M. Gilbert,⁵ V. Broeckner,⁶ L. Bow,¹ J. Pober.²
¹Surgery, Yale University, New Haven, CT; ²Immunobiology, Yale University, New Haven, CT; ³Yale Center for Analytical Sciences, Yale School of Public Health, New Haven, CT; ⁴Medicine, Yale University, New Haven, CT; ⁵Pathology, Yale University, New Haven, CT; ⁶Histopathology, Univeristy of Cambridge, Cambridge, United Kingdom.
Purpose: We hypothesize that de novo donor specific antibody (DSA) in kidney transplant patients cause endothelial cell injury that is dependent on complement and treatment…
2016 American Transplant Congress
Impact of Allograft Dysfunction and Early Low Grade Proteinuria on Survival in Expanded Criteria Donor Kidney Transplant Recipients.
V. López, M. Cabello, P. Ruiz, C. Jironda, D. Burgos, M. González-Molina, D. Hernández.
Nephrology, Hospital Regional de Málaga, Málaga, Spain.
Introduction. Recent studies have demonstrated a relationship between low-grade proteinuria and worse graft survival, but this has not been fully studied in expanded criteria donor…
2016 American Transplant Congress
Early Posttransplant Complications Following Abo-Incompatible Kidney Transplantation.
L. Rostaing,^1,2,3 A. Allal,¹ H. Naciri Benami,¹ Z. Abdulrahman,¹ L. Esposito,¹ F. Sallusto,¹ N. Doumerc,¹ X. Game,¹ B. Debiol,¹ N. Congy,¹ N. Kamar.^1,3,4
¹Néphrologie et Transplantation d'Organes, CHU Rangueil, Toulouse, France; ²INSERM U 563, CHU Purpan, Toulouse, France; ³Faculté de Médecine de Rangueil, Université Toulouse III Paul Sabatier, Toulouse, France; ⁴INSERM U1043 CNRS UMR 5282, CHU Purpan, Toulouse, France.
Introduction: Many studies or registries particularly in Japan, but also in Western Europe, have shown that long-term results from ABO-incompatible (ABOi) living-kidney transplantation are as…