2016 American Transplant Congress
Pathogenic Role of Anti-HLA Antibodies on Endothelial Progenitor Cell Dysfunction of Highly Sensitized Kidney Transplanted Patients.
Anti-HLA antibodies (abs) bind to kidney graft endothelial cells inducing complement-mediated injury and humoral rejection. Endothelial Progenitor Cells (EPC) are bone marrow-derived precursors able to…2016 American Transplant Congress
A2 Kidneys into B Recipients: Is Postoperative Anti-A1 Titer Monitoring Useful?
Kidney and Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, TN.
Background: Since the introduction of the new Kidney Allocation System in December 2014, our center implemented a protocol for transplanting A2 kidneys into B recipients…2016 American Transplant Congress
In Their Own Words: Living Kidney Donors Who Develop Kidney Failure.
Background: Psychosocial data about living kidney donation have been collected for almost five decades. The results are almost uniformly positive, even in the early years…2016 American Transplant Congress
Urine-Derived Cell Lines as a Novel Tool for Monitoring Allo-Reactivity in Kidney Transplant Patients.
Reactivity of the immune system against donor antigens determines transplant-rejection after transplantation, and analyzing the alloimmune response has been shown to predict acute rejection in…2016 American Transplant Congress
Late Outcome Surrogate Score (LOSS) for Kidney Allograft Failure.
Comprehensive Transplant Center, Northwestern University, Chicago, IL.
Background. Early outcomes following kidney transplant have steadily improved. Longer-term outcomes, while not the focus of regulatory oversight, are of vital importance. Clinical trials are…2016 American Transplant Congress
Do Morbidly Obese Patients Have an Increased Risk of Infection Post-Kidney Transplant?
Medical University of South Carolina, Charleston, SC.
Purpose: Obesity has been associated with significant morbidity in the kidney transplant population. The aim of this study was to assess the impact of obesity…2016 American Transplant Congress
A Selective Biomarker in Blood Cells Identifies IFTA After Kidney Transplantation.
Cellular and antibody-mediated rejection processes and also interstitial fibrosis/tubular atrophy (IFTA) lead to allograft dysfunction and loss. The search for accurate and specific diagnostic tools…2016 American Transplant Congress
Attitudes Toward Living Kidney Transplantation Among Potential Transplant Candidates.
1Yale U, New Haven; 2U Pennsylvania, Philadelphia; 3Northwestern U, Chicago.
Background: Prior studies have shown that transplant candidates who are minorities and less educated are less willing to talk to others about living kidney donor…2016 American Transplant Congress
A Comprehensive Biomarker Study to Compare Tacrolimus and Mycophenolic Acid versus Half-Dose Tacrolimus and Everolimus in De Novo Kidney Transplant Patients in the Novartis US92 Study.
In this exploratory biomarker sub-study, a comprehensive combined targeted/ non-targeted metabolomics and targeted proteomics approach was used to assess potential differences between the everolimus+ low-dose…2016 American Transplant Congress
Do We Need an Individually Tailored Immunosuppression Strategy for Living Donor Kidney Transplant Recipients with PreTransplant Donor Specific Antibodies? A Retrospective Analysis.
Introduction:Pre-Transplant Microbead donor HLA specific antibody(DSA) positive but cell crossmatch negative transplants are considered to be at increased immunological risk. This study aimed to address…
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