Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Biopsies for Delayed Graft Function After Alemtuzumab Induction in Kidney Transplantation: The Incidence of Early Rejection After Alemtuzumab Is Very Low but Not Negligible.
E. McGuire, C. Roufosse, T. Cook, D. Ashby, T. Cairns, J. Galliford, M. Willicombe, D. Taube, A. McLean.
Imperial Kidney & Transplant Centre, Hammersmith Hospital, Imperial College Healthcare, London, United Kingdom.
IntroductionUK practice advocates transplant biopsy (Bx) at day 7, then weekly in the presence of delayed graft function (DGF) because if missed, early rejection adversely…
2016 American Transplant Congress
Urinary Expression of miRNA-155, miRNA-210, miRNA-142 and CXCL-10 Production Predicts the Risk of Acute Rejection and Graft Outcome in Renal Transplant Recipients.
O. Millan,¹ K. Budde,² C. Sommerer,³ I. Aliart,¹ O. Rissling,² B. Bardaji,⁴ M. Matz,² M. Zeier,³ I. Silva,⁴ L. Guirado,⁴ M. Brunet.¹
¹Pharmacology Laboratory, CDB, IDIBAPS, Hospital Clinic Barcelona, Barcelona University, Barcelona, Spain; ²Medizinische Klinik mit Schwerpunkt Nephrologie, Charité Universitätsmedizin, Berlin, Germany; ³Department of Nephrology, University Hospital Heidelberg and Mannheim, Heidelberg, Germany; ⁴Renal Transplant Unit, Fundació Puigvert, Barcelona, Spain.
MicroRNAs (miRs) have been reported to play a role in immune system response. The results of several clinical trials have suggested that these molecules might…
2016 American Transplant Congress
Do Highly Sensitized Recipients Benefit from the Immunological Advantages of Zero Mismatched (0MM) Deceased Donors (DD) Kidney Allografts?
N. Elfadawy,¹ S. Flechner,² J. Schold.²
¹Internal Medicine, Case Western Reserve University, Cleveland, OH; ²Glickman urological and kidney institute, Cleveland Clinic, Cleveland, OH.
HLA 0MM DD transplants have superior outcomes compared with outcomes for grafts with ≥1 HLA mismatches, but when past reports analyzed 0MM outcomes in DD,…
2016 American Transplant Congress
Can We Predict New-Onset Diabetes After Transplantation Previously?
R. Imamura,¹ K. Tsutahara,² S. Nakazawa,¹ Y. Kakuta,¹ T. Abe,¹ T. Takao,² N. Ichimaru,³ S. Yamaguchi,² S. Takahara,³ N. Nonomura.¹
¹Urology, Osaka University Graduate School of Medicine, Suita, Japan; ²Urology, Osaka General Medical Center, Osaka, Japan; ³Advanced Technology for Transplantation, Osaka University Graduate School of Medicine, Suita, Japan.
Objectives: New-onset diabetes after transplantation (NODAT), one of the important complications after kidneytransplantation, leads to reduce graft survival rate and increase patient morbidity and mortality.…
2016 American Transplant Congress
Outcomes for Kidney Allograft Recipients with Language Barriers Post-Transplantation – A Comparative Analysis.
S. Tahir,¹ F. Jackson-Spence,¹ H. Gillott,¹ F. Everson,² J. Nath,² A. Sharif.²
¹University of Birmingham, Birmingham, United Kingdom; ²Queen Elizabeth Hospital, Birmingham, United Kingdom.
Introduction: Patients from ethnic minorities make up an increasing number of recipients of kidney allografts in the UK. Some of these patients have language barriers…
2016 American Transplant Congress
Does Pre-Emptive Transplantation Improve Survival Compared to Transplantation After Dialysis Among Deceased Donor Kidney Recipients?
J. Tao, C. Wu, W. Bannister, M. Schnitzler, A. Bonagura, B. Laihinen, F. Irwin.
Complex Medical Conditions, Optum, UnitedHealth Group, Eden Prairie, MN; Surgery, St Louis University, St Louis, MO.
Previous studies have shown that pre-emptive transplantation of kidneys from living donors is associated with longer graft survival than those who have initiated dialysis prior…
2016 American Transplant Congress
Significant Pharmacokinetic Interaction Between Everolimus and Tacrolimus in De Novo Renal Transplant Recipients.
H.-P. Chang,¹ C.-Y. Lee,² C.-C. Si,¹ M.-K. Tsai,² F.-L. Lin Wu.^1,3
¹Graduate Institute of Clinical Pharmacy, National Taiwan University, College of Medicine, Taipei, Taiwan; ²Surgery, National Taiwan University Hospital, College of Medicine, Taipei, Taiwan.
Studies on the effect of everolimus on tacrolimus pharmacokinetics (PK) were limited and the results were inconsistent. In contrast, studies showed there was little effect…
2016 American Transplant Congress
Kidney Donor Profile Index and Recipient BMI Are Potent Predictors of Six Month Deceased Donor eGFR as Opposed to EPTS.
A. Agarwal, W. Ally, D. Maluf, S. Pelletier, K. Brayman.
University of Virginia Health System, Charlottesville, VA.
Background: Kidney Donor Profile Index (KDPI) has been shown to be predictive of both short and long term graft survival and is used by transplant…
2016 American Transplant Congress
Renal Transplant in Obese Recipients: Consideration of Donor and Recipient Factors Can Improve Outcomes.
P. Stahler, J. Mezrich, G. Leverson, D. Kaufman, H. Sollinger.
Division of Transplantation, University of Wisconsin-Madison, Madison, WI.
Background: Obesity rates in the transplant population are increasing. Previous studies are limited by small sample sizes, short-term follow up, and conflicting results. Factors including…
2016 American Transplant Congress
The Significance of Microvascular Inflammation in Antibody-Mediated Rejection in ABO-Incompatible Kidney Transplantation.
H. Ishihara,¹ H. Ishida,¹ K. Unagami,² T. Hirai,¹ M. Okumi,¹ K. Omoto,¹ T. Shimizu,¹ K. Tanabe.¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan; ²Nephrology, Tokyo Women's Medical University, Tokyo, Japan.
Background: In ABO-incompatible (ABOi) transplantation, the criteria for antibody-mediated rejection (AMR) are controversial, as C4d deposition is common in ABOi. This study examined the impact…