Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Incidence of Post-Transplant Lymphoproliferative Disorder in First, Kidney-Only Transplant Recipients Remains Stable.
J. Molony,¹ Y. Peng,¹ N. Baker,² U. Meier-Kriesche,³ J. Snyder.¹
¹Chronic Disease Research Group, Minneapolis; ²Brystol-Myers Squibb Company (BMS), Hopewell; ³BMS, Lawrenceville.
We estimated the incidence of and risk factors for post-transplant (TX) lymphoproliferative disorder (PTLD) in the 3 years post-TX for adults with first, kidney-only TX…
2016 American Transplant Congress
Glomerular Capillary C4d Staining without Evidence of Rejection Is Associated with Worse Graft Function in ABO-Incompatible Kidney Transplantation.
D. Toki,¹ M. Inui,¹ M. Okumi,² H. Ishida,² K. Setoguchi,¹ T. Shimizu,² K. Unagami,² K. Tanabe.²
¹Urology, Tokyo Women's Medical University Yachiyo Medical Center, Chiba, Japan; ²Urology, Tokyo Women's Medical University, Tokyo, Japan.
Objectives: C4d staining in the peritubular capillaries (C4d-PTC) is often observed without evidence of rejection in ABO-incompatible kidney transplantation (ABOI-KTx), and this phenomenon is generally…
2016 American Transplant Congress
Induction Therapy in Low Risk African American Kidney Transplant Recipients: Donor Factors.
F. Al Ammary,¹ S. Bae,¹ A. Massie,¹ N. Dagher,¹ E. King,¹ A. Wiseman,² D. Segev.¹
¹JHU, Baltimore; ²CU, Denver.
African Americans (AA) are at a higher risk of acute rejection and graft loss compared to non-AA kidney transplant (KT) recipients. Guidelines specify induction choices…
2016 American Transplant Congress
Replacing Cold Storage with Normothermic Ex Vivo Kidney Perfusion Improves Function of Grafts Retrieved After Circulatory Death (DCD).
J. Kaths,^1,2 Y.-M. Chun,¹ D. Cen,¹ J. Echeverri,¹ I. Linares,¹ P. Yip,³ R. John,³ D. Bagli,⁴ I. Mucsi,⁵ A. Ghanekar,¹ D. Grant,¹ L. Robinson,² M. Selzner.¹
¹Department of Surgery, Multi Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada; ²Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada; ³Laboratory Medicine & Pathobiology, Toronto General Hospital, Toronto, ON, Canada; ⁴Departments of Surgery (Urology) & Physiology, The Hospital for Sick Children, Toronto, ON, Canada; ⁵Department of Medicine, Multi Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
Normothermic ex vivo kidney perfusion (NEVKP) and avoidance of static cold storage (SCS) is an attractive strategy to minimize injury of DCD kidney grafts. We…
2016 American Transplant Congress
End Stage Renal Disease (ESRD) Patients' Willingness to Accept Risks to Living Kidney Donors.
J. Gannon,¹ C. Thiessen,¹ K. Yu,¹ L. Skrip,¹ P. Reese,² E. Gordon,³ S. Kulkarni.¹
¹Yale University, New Haven; ²University of Pennsylvania, Philadelphia; ³Northwestern University, Chicago.
Background: While many potential living kidney donors (LKDs) are willing to accept high levels of ESRD risk, receipt of a living donor kidney is also…
2016 American Transplant Congress
Imminent Death Donation: Potential Effects on Organ Donation Numbers and Clinical Outcomes.
V. Potluri,¹ S. Nazarian,² M. Levine,² P. Reese.³
¹Internal Medicine, Lankenau Hospital, Wynnewood; ²Transplant Surgery, University of Pennsylvania, Philadelphia; ³Renal Division, University of Pennsylvania, Philadelphia.
Attempts at donation after cardiac death (DCD) lead to organ transplantation only among 70% of eligible DCDs. Imminent death donation (IDD) is ante-mortem donation of…
2016 American Transplant Congress
Universal Stenting of Renal Transplants Associated with a Low Complication Rate When Quality Assurance Program Ensures Stent Removal.
C. Yeast, J. Riley, C. Ashbaugh, G. Ross, M. Wakefield.
Urology, University of Missouri, Columbia, MO.
Introduction: The routine use of ureteral stents during renal transplantation remains controversial despite recent evidence that universal stenting decreases ureteric complications. Further, assurance of timely…
2016 American Transplant Congress
Patients with ESRD Due to Diabetes Have Higher Variability of Their Tacrolimus Levels and Worse Outcomes.
D. Goodall, M. Willicombe, A. McLean, D. Taube.
Imperial College Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom.
IntroductionNonadherence to immunosuppressants is associated with rejection and graft loss and nonadherence to antidiabetics is associated with poor glycaemic control leading to microvascular complications and…
2016 American Transplant Congress
Predicting the Ability of Anti-HLA Antibodies to Activate Complement.
D. Bekbolsynov, C. Baum, B. Mierzejewska, A. Malebari, M. Rees, S. Stepkowski.
University of Toledo, Toledo.
Purpose: The single antigen bead (SAB) assay measures binding of antibodies (Abs) to HLA in units of mean florescence intensity (MFI). Two assays measure the…
2016 American Transplant Congress
Graft Survival in Sensitized and Non-Sensitized Patients: Role of the Combination of Donor-Specific Antibodies and Acute Rejection.
P. Souza,¹ A. Aguirre,¹ G. Bezerra,² H. Rodrigues,² F. Agena,¹ D. David,¹ F. de Paula,¹ E. David-Neto,¹ M. Castro.¹
¹Renal Transplant Service, Hospital das Clínicas de São Paulo, Sao Paulo, Brazil; ²Immunology Laboratory, Instituto do Coração (InCor), Sao Paulo, Brazil.
Background: Sensitized (S) patients have higher risk for acute rejection (AR), especially ABMR. DSA is a risk fator for ABMR, however, its impact on AR…