Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Alemtuzumab Induction Allows Better Rejection Free Graft Survival in Comparison to Basiliximab Although with Increased Post Transplant Viral Infections.
V. Siddagangaiah,¹ H. Sharma,² N. Lal,¹ J. Rai,¹ M. Howse,¹ D. Ridgway,¹ A. Sharma,¹ A. Hammad,¹ S. Mehra.¹
¹Renal Transplant Surgery, Royal Liverpool and Broadgreen University Hospital, Liverpool, United Kingdom; ²Transplant Surgery, Manchester Royal Infirmary, Manchester, United Kingdom.
Introduction: 3C study concluded that in comparison to basiliximab, alemtuzumab induction reduces the risk of biopsy proven acute rejection (BPAR) in renal transplant recipients. In…
2016 American Transplant Congress
Immunosuppressive Actions of CLI95 and CORM401 on TLR4 in Renal Ischemia Reperfusion Injury.
P. Luke,^1,2,5 G. Cepinskas,^1,4 H. Alharbi,^3,5 A. Haig,^3,5 R. Bhattacharjee.^1,2,5
¹Matthew Mailing Centre, London Health Sciences Centre, London, Canada; ²Surgery, Western University, London, Canada; ³Pathology and Laboratory Medicine, Western University, London, Canada.
Background: Kidneys from all donor sources are highly sensitive to ischemia-reperfusion injury (IRI). However, grafts donated after cardiac death (DCD) sustain an increased incidence of…
2016 American Transplant Congress
Altruistic Kidney Donation: From the Donor's Perspetive.
R. Burge,¹ S. Potts,^2,3 S. Lundie.⁴
¹Edinburgh Medical School, University of Edinburgh, Edinburgh, United Kingdom; ²Department of Psychological Medicine, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom; ³Department of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom; ⁴Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
Introduction: Although all living kidney donors are offered yearly reviews post-transplant, the restricted contact time and medical focus limits understanding of the motivations and experiences…
2016 American Transplant Congress
Controlled Cardiac Death Donor Program for Kidney Transplantation – Spanish Multicenter Experience with Two Years of Follow-Up.
J. Portoles,¹ M. Perez-Saez,² D. Hernandez-Marrero,² O. Lafuente,¹ F. Diekmann,² N. Maruri Kareaga,² M. Rodriguez-Ferrero,² F. Llamas,² M. Mazuecos,² J. Juega,² E. Melilli,² A. Rodriguez-Benot,² A. Alonso,² J. Pascual.²
¹Nephrology, U.H.Puerta de Hierro-RedinRen, Majadahonda, Spain; ²Nephrology, SENTRA-GEODAS Group, Madrid, Spain.
Background: Controlled donation after cardiac death (cDCD) programs are running in several countries for years. National transplant organization (ONT) has developed a nation-wide program in…
2016 American Transplant Congress
Extraperitoneal Placement of the Kidney Prevents Graft Vascular Kinking or Rotation in Simultaneous Pancreas-Kidney Transplant (SPK).
M. Maraschio, A. Alcaraz, E. Giordano Segade.
Pancreas-Kidney Transplant Program, Hospital Privado Universitario de Córdoba, Cordoba, Argentina.
BACKGROUND: The preferred technique for kidney placement in SPK is intraperitoneal through a midline incision, as it is easy and fast to be performed. However,…
2016 American Transplant Congress
The Effect of Immunosuppression Regimen on Iga Nephropathy Recurrence Post Kidney Transplantation.
K. Koutroutsos,¹ A. Kousios,¹ L. Leighton,¹ R. Charif,¹ D. Goodall,¹ T. Cook,² J. Galliford,¹ D. Taube,¹ M. Loucaidou.¹
¹Renal and Transplant Centre, Imperial Healthcare NHS Trust, London, United Kingdom; ²Department of Histopathology, Imperial Healthcare NHS Trust, London, United Kingdom.
Background: Steroid sparing immunosuppression is increasingly used in order to avoid the many well-known side effects of steroids. It has been argued that steroid use…
2016 American Transplant Congress
Adenovirus Infection in Kidney Transplant Recipients: Report of a Case Series.
C. Simancas-Ruiz, L. Marino-Vazquez, A. Meraz-Muñoz, A. Nuñez-Abreu, R. Rivera-Marfil, N. Uribe-Uribe, J. Alberu, L. Morales-Buenrostro.
Nephrology, Transplant and Pathology, National Institute of Medical Sciences and Nutrition SZ, México, DF, Mexico.
Introduction: In kidney transplant recipients, the incidence of adenovirus infection is 4.1%, usually occur in the first three months after transplantation. Patients may have viral…
2016 American Transplant Congress
Kidney Transplantation with Strong Preformed Donor-Specific Antibodies: Impact of C1q-Binding Ability.
J. Malheiro,¹ S. Tafulo,² S. Santos,¹ M. Costa,¹ L. Martins,¹ L. Dias,¹ A. Henriques.¹
¹Nephrology, CHP, Porto, Portugal; ²CSTP, Porto, Portugal.
HLA-incompatible kidney transplantation is associated with worse outcomes given the presence of donor-specific anti-HLA antibodies (DSA). Our aim was to investigate the association between preformed…
2016 American Transplant Congress
Rapid Detection of Acute Infection in Immunosuppressed Renal Patients with IRIDICA: A Pilot Study.
S. Hassan,¹ A. Adwaney,¹ A. Massiah,² R. Murphy,² S. Law,¹ S. Mohd-Afzal,¹ M. Wilks,² R. Thuraisingham.¹
¹Renal, Royal London Hospital, Barts Health Trust, London, United Kingdom; ²Microbiology, Barts Health Trust, London, United Kingdom.
BackgroundThe Abbott IRIDICA bacterial bloodstream (BAC BSI) assay is a rapid semi-quantitative diagnostic test that is able to detect over 800 significant pathogens using PCR…
2016 American Transplant Congress
Genomic-Derived Markers to Identify Calcineurin Inhibitor Nephrotoxicity in Pediatric Kidney Transplant Recipients.
E. Rhone,¹ R. Gehrau,² S. Bontha,² P. Walker,³ C. Dumur,⁴ D. Maluf,² V. Mas.²
¹Pediatrics, University of Virginia, Charlottesville, VA; ²Surgery, University of Virginia, Charlottesville, VA; ³Nephropath, Little Rock, AR; ⁴Pathology, Virginia Commonwealth University, Richmond, VA.
Background:Calcineurin inhibitor nephrotoxicity (CNIT) is a well-known contributor to chronic allograft dysfunction in kidney transplant recipients (KTRs). Pediatric KTRs are particularly at risk given their…