Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Incidence of Posttransplant Lymphoproliferative Disorder with Belatacept Therapy versus Calcineurin Inhibitor Therapy Alone: Data from One Academic Medical Center
K. Addonizio¹, G. Petrossian¹, A. Hsiao¹, L. Teixeira¹, N. Koizumi², R. James², S. Patel³, R. Plews¹, D. Conti¹, J. Ortiz¹
¹Division of Renal and Pancreatic Transplant Services, Albany Medical Center, Albany, NY, ²George Mason University, Fairfax, VA, ³UMC Las Vegas, Las Vegas, NV
*Purpose: To compare rates of post-transplant lymphoproliferative disorder (PTLD) in patients treated with Belatacept and low-dose calcineurin inhibitors (CNIs) versus patients only treated with standard-dose…
2022 American Transplant Congress
Study of the Composition of the Inflammatory Burden on a Cohort of 125 Rejections by Multiplex Immunofluorescence
A. Mobio¹, M. Eloudzeri², L. Morin¹, J. Duong Van Huyen³, D. Anglicheau¹, M. Rabant³
¹Kidney transplantation, Necker-Enfants Malades Hospital, Paris, France, ²U1151, INEM, Paris, France, ³Pathology, Necker-Enfants Malades Hospital, Paris, France
*Purpose: The exact composition of the inflammatory burden during kidney transplant rejection has not been studied on large cohorts. Moreover, the determinants and impact of…
2022 American Transplant Congress
Obinutuzumab in Kidney Transplantation: Effect on B-cell Counts and Crossmatch Tests
M. M. Nasrallah¹, M. Elalfy¹, Y. Elmesseery², I. Amer¹, P. Malvezzi³, L. Rostaing⁴
¹Misr International Hospital, Cairo, Egypt, ²Misr International Hospital, Caire, Egypt, ³CHU Grenoble-Alpes, Grenoble, France, ⁴Service de Néphrologie, CHU Grenoble-Alpes, Grenoble, France
*Purpose: Resistance to the action of rituximab (RTX), has been documented in several diseases. More recently, obinutuzumab (OBZ) has shown promise where RTX has failed…
2022 American Transplant Congress
The Effect of Late-Onset Cytomegalovirus Infection on the Outcome of Renal Allograft in Patients with Delayed Graft Function
M. Rahimi Shahmirzadi¹, M. Silverman¹, L. Gunaratnam², A. Jevnikar², A. A. House², S. Hosseini-Moghaddam³
¹Infectious Diseases Care Program, St. Joseph's Health Care London, London, ON, Canada, ²London Health Sciences Centre, London, ON, Canada, ³St. Joseph's Health Care London, London, ON, Canada
*Purpose: Delayed graft function (DGF) has been reported to increase the risk of renal allograft loss. The role of late-onset Cytomegalovirus infection in the association…
2022 American Transplant Congress
Knowledge, Attitude, and Practices Regarding Covid-19 Among Solid Organ Transplant Patients at a Transplant Center in the United States: A Cross-Sectional Study
L. Wang, H. Oduor, M. Abualfoul, P. Acharya, M. Pagadala
Methodist Dallas Medical Center, Dallas, TX
*Purpose: To evaluate the knowledge, attitude, and practices (KAP) of patients who have undergone kidney and/or liver solid organ transplants (SOTs) during the COVID-19 pandemic.*Methods:…
2022 American Transplant Congress
Very Low Frequency of Pathological Findings in One-Year Protocol Biopsies of Low-Risk Kidney Transplant Recipients – Results from the Nordic Protocol Biopsy Study
I. Helanterä¹, C. Dörje², F. Ortiz³, A. Varberg Reisæter², C. Hammarstrøm², J. Lauronen⁴, A. Räisänen-Sokolowski⁵, A. J. Haugen⁶, M. Lempinen¹, A. Åsberg², G. Mjøen²
¹Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland, ²Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway, ³Nephrology, Helsinki University Hospital, Helsinki, Finland, ⁴Histocompatibility Laboratory, Finnish Red Cross Blood Service, Helsinki, Finland, ⁵Department of Pathology, Helsinki University Hospital, Helsinki, Finland, ⁶Medical Department, Bærum Hospital, Bærum, Norway
*Purpose: The clinical usefulness of kidney graft protocol biopsies have been debated. We studied the frequency of borderline and T-cell-mediated rejection (TCMR) in one-year protocol…
2022 American Transplant Congress
Assessment of Humoral and Cellular Immune Responses to Sars Cov-2 Vaccination in Immunocompromised Renal Allograft Recipients
B. Shin, R. Zhang, T. M. Gadsden, A. Petrosyan, A. Vo, N. Ammerman, S. Sethi, E. Huang, A. Peng, R. Najjar, J. Atienza, I. Kim, S. C. Jordan
Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: SARS CoV-2 vaccination elicits both robust humoral and T-cell immune responses in healthy individuals. However, a comprehensive assessment of immune responses to SARS-CoV-2 vaccination…
2022 American Transplant Congress
Single Port Robotic Kidney Transplantation: Comparison of Outcomes with Standard Open Kidney Transplantation
M. Eltemamy, A. Kaviani, Y. Lin, M. Abou Zeinab, V. Krishnamurthi, D. Goldfarb, J. Kaouk, A. Wee
Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH
*Purpose: To compare outcomes of the initial series of patients who underwent single port (SP) robotic kidney transplantation (KTP) with the standard open KTP.*Methods: Using…
2022 American Transplant Congress
Quantification of Center Aggressiveness in Accepting Sub-Optimal Kidney Donations from Deceased Donors in the US
T. P. Chiang¹, M. Eagleson¹, A. Massie¹, M. Krach¹, D. Segev¹, J. Garonzik Wang²
¹Department of Surgery, Johns Hopkins University, Baltimore, MD, ²School of Medicine and Public Health, University of Wisconsin, Madison, WI
*Purpose: Understanding center-level differences in usage of marginal deceased-donor kidneys (suboptimal kidneys, SOK) can help centers increase their deceased-donor transplant rate (DDKT), and to direct…
2022 American Transplant Congress
Blood Transcriptomes of Kidney Recipients with Covid-19 Demonstrate Deficient Adaptive Immune Activation
K. Banu¹, Z. Sun², Y. A. Azzi³, M. M. Rana⁴, A. Reghuvaran¹, G. Carrara⁵, S. Hartell⁴, W. Asch¹, W. Zhang⁴, Z. Zhang², E. Akalin³, P. Cravedi², P. Heeger², K. Banu¹
¹Nephrology, Yale University, New Haven, CT, ²Icahn School of Medicine at Mount Sinai, New York, NY, ³Montefiore Medical Center, New York, NY, ⁴Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY, ⁵Icahn School of Medicine at Mount Sinai, New Haven, CT
*Purpose: Kidney transplant recipients (KTRs) have poor outcomes compared to non-KTRs with acute COVID-19. To provide insight into management of immunosuppression (IS) during COVID-19, we…