Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Successful Implementation of a Rural Appalachian Kidney Transplant Program; One Year Outcomes
F. Afridi¹, B. Gillis¹, R. Lopez¹, D. Kannabhiran¹, V. Chaudhary¹, M. Thornberg¹, R. Zomak¹, K. Meyer¹, C. Newman¹, L. Biondi²
¹Department of Surgery, West Virginia University, Morgantown, WV, ²Department of Surgery, West Virginia University, Morgantown, WV, WV
*Purpose: Kidney transplantation has become the optimal treatment for end stage renal disease (ESRD), allowing dialysis free survival. Despite widespread availability of transplant programs; rural…
2022 American Transplant Congress
Impact of the Second Year COVID-19 Pandemic on the U.S. Kidney Transplantation: Interrupted Time Series Analysis
E. Tantisattamo¹, N. Polpichai², P. Mutirangura³, M. Tanariyakul⁴
¹Division of Nephrology, Hypertension and Kidney Transplantation, Department of Medicine, University of California Irvine School of Medicine, Orange, CA, ²Faculty of Medicine Songklanagarin Hospital, Prince of Songkla University, Songkhla, Thailand, ³Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, ⁴Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
*Purpose: The number of kidney transplant (KT) was decreased since the COVID-19 pandemic; however, the magnitude of the pandemic on the number of U.S. KT…
2022 American Transplant Congress
Plasma Donor-Derived Cell-Free DNA Longitudinal Kinetics After Kidney Transplantation in Children
R. Dandamudi¹, S. Federman², R. Woodward², S. Dholakia², L. Walther¹, V. Dharnidharka¹
¹Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, ²CareDx, Brisbane, CA
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) are DNA fragments released continuously into circulation from injured donor allograft cells. In adult studies, the levels drop to a…
2022 American Transplant Congress
Long-Term Kidney Allotransplant Acceptance is Defined by a Shift from a T Cell to a B Cell Rich Immune Microenvironment Within the Graft
E. S. Szuter¹, T. Yokose¹, M. T. Guinn¹, J. Ge², I. Rosales³, B. Kwon⁴, P. S. Russell¹, A. Cuenca², D. Kreisel⁵, P. Sage⁶, J. C. Madsen¹, R. B. Colvin³, A. Alessandrini¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Department of Surgery, Boston Children's Hospital, Boston, MA, ³Department of Pathology, Massachusetts General Hospital, Boston, MA, ⁴Harvard College, Cambridge, MA, ⁵Department of Surgery, Washington University, St. Louis, MO, ⁶Transplantation Research Center, Renal Division, Brigham and Women’s Hospital, Boston, MA
*Purpose: Mouse kidney allografts are spontaneously accepted in select, fully-mismatched donor-recipient strain combinations, such as DBA/2J to C57BL/6 (B6). Tolerant renal grafts develop aggregates of…
2022 American Transplant Congress
An Acceptable Challenge for Specialized Transplant Centres: Small Kidney Donors for Small Recipients
R. Büscher, M. Cetiner, P. F. Hoyer, A. K. Büscher
Department of Pediatrics II, University Hospital Essen, Essen, Germany
*Purpose: Kidneys from small donors (SDK, donor weight
2022 American Transplant Congress
Costs Associated with Induction Therapy for Pediatric Kidney Transplantation
N. M. Rodig¹, H. Pizzo², D. Levy Erez³, T. Richardson⁴, M. Somers¹
¹Boston Children's Hospital, Boston, MA, ²Cedars-Sinai Medical Center, Los Angeles, CA, ³Children’s Hospital of Philadelphia, Philadelphia, PA, ⁴Children's Hospital Association, Lenexa, KS
*Purpose: Choice of induction agent for pediatric kidney transplantation (KTx) is often based upon patient characteristics and center practice; costs associated with this choice have…
2022 American Transplant Congress
COVID-19 Infection Post-Transplant: What is the Collateral Damage to the Graft? A Case for Pre-Transplant Vaccination
A. Fabick¹, E. Overly¹, V. Rao², V. Rohan³, N. Patel¹, D. DuBay³, C. Candland³, N. Pilch¹
¹Department of Pharmacy, Medical University of South Carolina, Charleston, SC, ²Department of Transplant Nephrology, Medical University of South Carolina, Charleston, SC, ³Department of Transplant Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: COVID-19 produces an unpredictable immune reaction and is challenging to manage during active infection and post-infection, in kidney transplant (KTX) recipients. The first peak…
2022 American Transplant Congress
Baseline Trends in Tacrolimus Intrapatient Variability in Pediatric and Young Adult Kidney Transplant Recipients
K. Piburn¹, L. Maestretti², M. V. Patton², A. M. McGrath², O. S. Indridason³, A. Chaudhuri¹, P. Grimm¹, V. Sigurjonsdottir¹
¹Pediatric Nephrology, Stanford University, Palo Alto, CA, ²Pediatric Kidney Transplant, Lucile Packard Children's Hospital, Palo Alto, CA, ³Division of Nephrology, Landspitali – the National University Hospital of Iceland, Reykjavik, Iceland
*Purpose: High tacrolimus intrapatient variability (IPV) is a known risk factor for poor graft outcomes in kidney transplantation. Baseline trends in tacrolimus IPV have not…
2022 American Transplant Congress
Parathyroidectomy versus Cinacalcet in the Treatment of Tertiary Hyperparathyroidism After Kidney Transplantation
C. Baek
Asan Medical Center, Seoul, Korea, Republic of
*Purpose: Hyperparathyroidism is prominent in patients with chronic kidney disease with reduced renal function and has been observed after kidney transplantation. There is a debate…
2022 American Transplant Congress
Impact of Donor Quality on Outcomes for AKI and Non-AKI Kidneys with and without DGF
C. Jadlowiec¹, P. Budhiraja², R. Butterfield¹, M. Smith³, A. K. Mathur¹, A. Moss¹, H. Khamash², K. Reddy¹, R. Heilman²
¹Mayo Clinic Arizona, Phoenix, AZ, ²Division of Transplant Nephrology, Mayo Clinic Arizona, Phoenix, AZ, ³Division of Anatomic Pathology, Mayo Clinic Arizona, Phoenix, AZ
*Purpose: The relevance of DGF, and whether it is clinically significant, continues to be debated. Our aim was to compare post-transplant outcomes between AKI and…