Articles tagged "Kidney transplantation"

2022 American Transplant Congress
De Novo DSA in the Setting of Stable Allograft Function is a Benign Finding
R. J. Knight, E. A. Graviss, D. T. Nguyen, T. N. Eagar, S. G. Yi, H. Podder, M. Hobeika, R. McMillan, A. O. Gaber
Houston Methodist Hospital, Houston, TX
*Purpose: We sought to determine the long-term outcome of renal allografts that developed de novo DSA (dnDSA) in the setting of stable renal function.*Methods: A…
2022 American Transplant Congress
Anti-HLA Antibodies Do Not Increase in Kidney Transplant Recipients During COVID-19 Infection
A. Girnita¹, L. Wang¹, P. Ahearn¹, A. Colovai², M. Fernandez-Vina¹, E. Woodle³, T. Yalamarti¹, M. Menon⁴, Y. Azzi², M. Melcher¹, R. Bray⁵, H. Gebel⁵, P. Cravedi⁴, J. Maltzman¹, E. Akalin²
¹Stanford University, Palo Alto, CA, ²Albert Einstein College of Medicine, New York, NY, ³University of Cincinnati, Cincinnati, OH, ⁴Mount Sinai, New York, NY, ⁵Emory University Hospital, Atlanta, GA
*Purpose: To determine if HLA allo-antibody levels are affected by COVID-19 in renal transplanted patients and to compare the immunoglobulin class and subclass profiles as…
2022 American Transplant Congress
Baseline Findings from the UREAACT Trial to Improve Medication Adherence in Youth with Kidney Transplants
S. Amaral¹, P. Kwong², J. Zhu², R. George³, N. Rodig⁴, B. Warady⁵, J. Smith⁶, A. Bobrowski⁷, D. Matossian⁸, N. Zelikovsky⁹, L. Schwartz¹, P. Reese², R. Goldfarb Terry¹, J. Reason², A. Chung¹, S. Furth¹
¹CHOP, Phila, PA, ²UPenn, Phila, PA, ³CHOA, Atlanta, GA, ⁴Boston Children's, Boston, MA, ⁵Children's Mercy, Kansas City, MO, ⁶Seattle Children's, Seattle, WA, ⁷Cleveland Clinic, Cleveland, OH, ⁸Lurie Children's, Chicago, IL, ⁹LaSalle Univ, Phila, PA
*Purpose: This abstract describes the design and baseline characteristics of participants in the U-REAACT trial, a study to improve medication adherence in youth with kidney…
2022 American Transplant Congress
Impact of Maintaining Blood Pressure Goals on Graft Function After Kidney Transplant
D. Majmundar, A. DiCarlo, S. Karhadkar, A. Diamond, K. Mohrien, P. Szczesniak
Temple University Hospital, Philadelphia, PA
*Purpose: Impaired graft function following kidney transplant impacts short- and long-term patient outcomes. Proper management of systolic blood pressure (SBP) in the immediate post-operative period…
2022 American Transplant Congress
The Impact of Frailty Syndrome on Humoral Response to SARS-CoV-2 mRNA Vaccines in Older Kidney Transplant Recipients
M. Schmalz¹, H. Vankova², S. Rajnochova-Bloudickova¹, P. Hruba³, M. Fialova⁴, J. Gurka⁵, M. Magicova¹, I. Striz⁴, I. Zahradka¹, O. Viklicky¹
¹Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ²The Third Faculty of Medicine, Charles University, Prague, Czech Republic, ³Transplantation Laboratory, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁴Department of Immunology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁵Department of Information Technology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Advanced age is associated with impaired humoral immune response to SARS-CoV-2 mRNA vaccines in kidney transplant recipients (KTR), however mechanisms are poorly understood. Frailty…
2022 American Transplant Congress
Efficacy and Safety of Angiotensin II Compared to Catecholamine Vasopressors as a First-Line Vasopressor for Perioperative Hypotension in Kidney Transplant Recipients
G. Urias¹, J. Benken¹, A. Lichvar², D. Pierce¹, L. Andrews¹, K. Dalton³, A. Datta¹, H. Nishioka¹, E. Benedetti¹, S. Benken¹
¹University of Illinois at Chicago, Chicago, IL, ²University of California San Diego Health, San Diego, CA, ³St. David's Healthcare, Austin, TX
*Purpose: Perioperative use of catecholamine vasopressors (CV) in kidney transplantation (KT) have been associated with negative renal outcomes and the development of arrhythmias. A more…
2022 American Transplant Congress
Glucose Variability in Kidney Transplantation: Pre-Transplant and Post-Transplant Continuous Glucose Monitoring
E. Jo¹, A. Han², S. Min², J. Ha³, H. Lee⁴, A. Cho⁵
¹Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, ²Seoul National University College of Medicine, Seoul, Korea, Republic of, ³Seoul Nat'l Univ. College of Medicine, Seoul, Korea, Republic of, ⁴Seoul National University Hospital, Seoul, Korea, Republic of, ⁵Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of
*Purpose: Continuous glucose monitoring (CGM) provides a 24-hour view of glucose values and information on glycemic variability and additional indices such as the glucose management…
2022 American Transplant Congress
Associated Factors to Physical Inactivity of Kidney Transplant Patients: Subproject of ADHERE Brazil Multicenter Study
E. S. Sertorio¹, F. A. Colugnati¹, K. Denhaerynck², S. De Smet³, J. O. Medina⁴, M. M. Reboredo⁵, S. De Geest², H. Sanders-Pinheiro¹, T. ADHERE BRAZIL Study team¹
¹Nephrology, Federal University of Juiz de Fora, Juiz de Fora, Brazil, ²Department of Public Health, Institute of Nursing Science, University of Basel, Basel, Switzerland, ³Transplant Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ⁴Nephrology, Hsopital do Rim, Federal University of São Paulo, São Paulo, Brazil, ⁵Pneumology, Federal University of Juiz de Fora, Juiz de Fora, Brazil
*Purpose: Even though regular physical activity is a current recommendation for kidney transplant recipients (KTR), results from ADHERE Brazil study revealed a high prevalence of…
2022 American Transplant Congress
Long-Term (>1 Year) Rejection Free Graft Survival of Kidney Xenografts with Triple Xenoantigen Knockout and Multiple Human Transgenes in Cynomolgus Monkeys
T. Hirose¹, G. Lassiter¹, D. Ma¹, A. D'Attilio¹, I. Rosales¹, D. Cloonan¹, R. Matheson¹, R. Colvin¹, W. Qin², Y. Kan², J. Layer², R. Anand², V. Paragas², L. Queroz², X. Tan², I. Kohnle², K. Stiede², K. Hall², M. Youd², M. Curtis², J. Markmann¹, T. Kawai¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²eGenesis Inc, Cambridge, MA
*Purpose: Pigs with deletion of 3 carbohydrate xenoantigens (triple knock-out, TKO) are expected to be optimal donors for human xenotransplantation. We have previously shown that…
2022 American Transplant Congress
Clinical Evolution of Patients with De Novo DSA After Kidney Transplantation
C. López del Moral¹, N. Lachmann², S. Hergovits², D. Stauch², A. Akifova³, M. Naik³, B. Osmanodja³, D. Schmidt³, K. Budde³
¹Nephrology department-IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²Institute for Transfusion Medicine, HLA-Laboratory, Charité - Universitätsmedizin, Berlin, Germany, ³Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin, Berlin, Germany
*Purpose: De novo donor-specific antibodies(dnDSA) are related to antibody-mediated rejection(ABMR), but the evolution of patients after dnDSA is variable and not always ABMR and graft…