Articles tagged "Kidney transplantation"

2022 American Transplant Congress
The Ontario Anatomic Kidney Score (OAKS) : Quantitative Macroscopic Assessment versus Histological Grading in Pre-transplant Evaluation of Donor Kidneys
J. Mello Offerni¹, D. Matty², H. Abed³, P. Roshanov⁴, A. Sener¹, P. Luke¹
¹Urology, Western University, London, ON, Canada, ²Undergraduate Medical Education, Western University, Schulich School of Medicine & Dentistry, London, ON, Canada, ³Division of Urology, Department of Surgery, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada, ⁴Division of Nephrology, Department of Internal Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada
*Purpose: Quantitative gross assessment of a kidney has not been used to influence the evaluation to utilize a kidney for transplantation. The Ontario Anatomic Kidney…
2022 American Transplant Congress
New Oral Anticoagulants vs Warfarin in Kidney Transplant
S. R. Raslan¹, D. Alkortas²
¹Pharmaceutical Care, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, ²KFSH & RC, Riyadh, Saudi Arabia
*Purpose: New oral anticoagulants (NOACs) have replaced warfarin due to their similar efficacy and better safety profile in the general population (GP). The risk of…
2022 American Transplant Congress
Clear Gender Disparity in Living Donor Kidney Transplants
A. C. Gruessner¹, R. Gruessner²
¹Medicine, SUNY Downstate Medical Center, Brooklyn, NY, ²SUNY Downstate Medical University, Brooklyn, NY
*Purpose: Over the last years, the number of kidney transplants from living donors (LD) increased. However, more male than female patients received a LD transplant…
2022 American Transplant Congress
The Association Between Renal Anatomy Data and Kidney Utilization
A. M. Placona, C. Martinez, K. McCharen, B. Shean, M. Stuart
United Network for Organ Sharing, Richmond, VA
*Purpose: Renal anatomy data, such as hard arterial plaque or discoloration, can be available as PDF attachments uploaded to DonorNet during the organ evaluation process.…
2022 American Transplant Congress
Everolimus Alleviates Renal Allograft Interstitial Fibrosis by Inhibiting Epithelial to Mesenchymal Transition Not Only via Inducing Autophagy but Also via Stabilizing iκB-α
Z. Gui¹, W. Zijie², M. Zheng³, M. Gu¹, R. Tan³
¹Department of Urology, The Second Affiliated Hospital with Nanjing Medical University, Nanjing, China, ²Jiangsu Province Hospital, Nanjing, China, ³Department of Urology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China
*Purpose: Chronic allograft dysfunction (CAD) is the major cause of late graft loss in long-term renal transplantation. In our previous study, we found Epithelial-mesenchymal transition…
2022 American Transplant Congress
Wide Spectrum of Molecular Injury Highlights Heterogeneity of Banff Tubulitis and Interstitial Inflammation Lesions
M. J. Ellis¹, T. Maw², E. Huang³, E. Stites⁴, F. Shihab⁵, D. C. Brennan⁶, G. Shekhtman⁷, N. Agrawal⁷, J. Zeng⁷, S. Kung⁸
¹Duke University, Durham, NC, ²University of Southern California, Los Angeles, CA, ³Cedars-Sinai Medical Center, Los Angeles, CA, ⁴University of Colorado, Aurora, CO, ⁵University of Utah, Salt Lake City, UT, ⁶Johns Hopkins School of Medicine, Baltimore, MD, ⁷CareDx, Brisbane, CA, ⁸University of California, San Francisco, San Francisco, CA
*Purpose: The pathological definition and clinical significance of borderline T cell-mediated rejection (BL-TCMR) remains an area of active debate, leading to inconsistencies in therapeutic strategy.…
2022 American Transplant Congress
Use of Kidneys from Hepatitis C Nat Positive Donors for Uninfected Recipients: Early Results from a Rural Appalachian Kidney Transplant Program
B. Gillis¹, F. Afridi¹, R. Lopez¹, V. Chaudhary¹, D. Kannabhiran¹, C. Fagella¹, R. Zomak¹, K. Meyer¹, M. Thornberg¹, L. Biondi²
¹Department of Surgery, West Virginia University, Morgantown, WV, ²Department of Surgery, West Virginia University, Morgantown, WV, WV
*Purpose: Increasing mismatch between kidneys available for transplant and the number of patients on the transplant wait list has led to research into novel sources…
2022 American Transplant Congress
Revolutionizing Clinical Diagnostic Models for Acute Rejection Using Generative Adversarial Networks
W. Yazar¹, R. Nijor¹, R. Sarwal¹, N. Titzler¹, M. Sarwal², S. Ghosh¹
¹Nephrosant, Brisbane, CA, ²NephroSant, Brisbane, CA
*Purpose: Data heterogeneity, incompleteness and class-imbalance, hallmarks of real world healthcare data (RWHD), pose long-standing challenges to the accuracy of AI-based models. This research evaluates…
2022 American Transplant Congress
Clinical Significance of Chronic Active T-cell Mediated Rejection in Renal Transplant Biopsies
C. T. Chung¹, A. Han², H. Kim³, S. Min², J. Ha²
¹Department of Surgery, Inha University Hospital, Incheon, Korea, Republic of, ²Seoul National University College of Medicine, Seoul, Korea, Republic of, ³Department of Surgery, Korea University Guro Hospital, Seoul, Korea, Republic of
*Purpose: Chronic active T-cell mediated rejection (CATCMR) was newly added to the Banff classification in 2017. Currently, its response to treatment, natural course, clinical significance…
2022 American Transplant Congress
A Hybrid Model Combining Survival Analysis, Knapsack Optimization and Supervised Learning to Extrapolate the Evolution of Kidney Transplantation Patients from Donors with Expanded Criteria After Controlled Circulatory Death
F. Santos Arteaga¹, D. Di Caprio², O. Bestard³, N. Montero⁴, F. Moreso³, M. Crespo⁵, C. Facundo⁶, J. Reinoso-Moreno⁷, D. Cucchiari⁷, B. Bayes⁷, E. Poch⁷, J. M. Campistol⁷, F. Oppenheimer⁷, F. Diekmann⁷, I. Revuelta⁷
¹Faculty of Economics and Management, Universidad Complutense de Madrid, Madrid, Spain, ²Department of Economics and Management, University of Trento, Trento, Italy, ³Department of Nephrology and Kidney Transplant, Hospital Universitari Vall Hebrón, Barcelona, Spain, ⁴Department of Nephrology and Kidney Transplant, Hospital Universitari de Bellvitge, Barcelona, Spain, ⁵Department of Nephrology and Kidney Transplant, Hospital del Mar, Barcelona, Spain, ⁶Department of Nephrology and Kidney Transplant, Fundació Puigvert, Barcelona, Spain, ⁷Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain
*Purpose: Kidney transplantation (KT) with expanded criteria donors (ECD) after controlled circulatory death (cDCD) in high-risk patients is being debated. We categorize patients via a…