ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2017 American Transplant Congress

    TNF[part]-I After Kidney Transplantation.

    B. Muth, B. Astor, D. Mandelbrot.

    Department of Medicine, Division of Nephrology, University of Wisconsin, Madison, WI

    Infliximab, adalimumab and etanercept are monoclonal antibodies which inhibit tumor necrosis factor alpha (TNF[part]-I) and are used in the treatment of inflammatory diseases such as…
  • 2017 American Transplant Congress

    The Effiency and Safety of Chemotherapy for Urothelial Carcinoma in Post-Kidney Transplanted Patients.

    Y. Zhu, J. Lin.

    Urology, Capital Medical University Beijing Friendship Hospital, Beijing, China

    Objective: According to our published data, upper tract urothelial carcinoma (UTUC) is the predominant malignancy among Chinese renal transplanted patients. This is quite different from…
  • 2017 American Transplant Congress

    Analysis of ApoL1 and MYH9 Genetic Polymorphisms Among the Hispanic Kidney Allograft Recipients.

    Y. Chang,1,2 T. Shah,1,3 D. Min.1

    1Western University of Health Sciences, Pomona, CA; 2Mendez National Institute of Transplantation Foundation, Los Angeles, CA; 3St. Vincent Medical Center, Los Angeles, CA

    Introduction: Genetic polymorphisms of Apolipoprotein 1 (ApoL1) and non-muscle heavy chain 9 (MYH9) genes are known to be strongly associated with focal segmental glomerulosclerosis, HIV-associated…
  • 2017 American Transplant Congress

    Personalized Tacrolimus (TAC) Dosing Using Genetic Variants in Caucasian Kidney Transplant (Tx) Recipients.

    D. Margraf,1 R. Brundage,1 D. Schladt,2 W. Guan,3 B. Wu,3 R. Remmel,4 C. Dorr,2,7 D. Berglund,1 R. Mannon,5 A. Matas,6 W. Oetting,1 A. Israni,2,7 P. Jacobson,1 For the DeKAF Genomics Investigators.

    1Dept of Experimental and Clinical Pharmacology, Col of Pharmacy, Univ of Minnesota(UMN), Mpls, MN; 2Chronic Disease Research Group, MPLS Medical Research Foundation, Mpls, MN; 3Div of Biostatistics, School of Public Health, UMN, Mpls, MN; 4Dept of Med Chem, Col of Pharmacy, UMN, Mpls, MN; 5Dept of Nephrology, Univ of Alabama, Birmingham, AL; 6Div of Transplantation, Dept of Surgery, School of Medicine, UMN, Mpls, MN; 7Dept of Nephrology, Hennepin County Medical Center, School of Medicine, UMN, Mpls, MN

    TAC is an immune suppressant with a narrow therapeutic index and high pharmacokinetic (PK) variability leading to uncertainty in blood concentrations. We previously developed an…
  • 2017 American Transplant Congress

    Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Dosing.

    D. Hesselink,1 L. Andrews,2 B. de Winter,2 J. Tang,3 N. Shuker,2 R. Bouamar,2 R. van Schaik,4 B. Koch,2 T. Van Gelder.1

    1Internal Medicine, Erasmus MC, Rotterdam, Netherlands; 2Hospital Pharmacy, Erasmus MC, Rotterdam, Netherlands; 3Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China; 4Clinical Chemistry, Erasmus MC, Rotterdam, Netherlands

    Bodyweight-based dosing of tacrolimus (Tac) is considered standard care, even though the available evidence is thin. An increasing proportion of transplant recipients is overweight, prompting…
  • 2017 American Transplant Congress

    Pre-Transplant Panel Reactive T Cells (PRT) with IL-15 as a Risk-Stratifier of Acute Rejection in Kidney Transplant Patients on Belatacept Therapy.

    P. Cravedi,1 I. Gandolfini,1 C. Donadei,1 R. Fairchild,2 K. Newell,3 R. Mannon,4 P. Heeger,1 CTOT16 Consortium.

    1Dept of Medicine, Icahn School of Medicine at Mount Sinai, New York; 2Dept of Immunology, Cleveland Clinic, Cleveland; 3Dept of Surgery, Emory University, Atlanta; 4Renal Division, UAB, Birmingham

    While kidney transplant recipients treated with bela without calcineurin inhibitors (CNI) have better 5-10y eGFR versus those on CNI, Belatacept (bela) use is associated with…
  • 2017 American Transplant Congress

    Obesity Is an Important Factor in Deceased but Not Living Donor Kidney Transplants.

    A. Asderakis, A. Ilham, U. Khalid, R. Chavez.

    Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom

    Introduction There is an increasing obesity among potential kidney transplant recipients. We had in the past shown that obesity did increase the wound infection rate,…
  • 2017 American Transplant Congress

    Single Kidney Transplantation from Pediatric Donors Younger Than 3 Years to Adult Recipients.

    L. Zhu, B. Liu, S. Chang, D. Du, N. Gong, J. Jiang, Z. Chen, G. Chen.

    Tongji Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

    Background: Traditionally, the criteria of splitting pediatric en bloc kidneys for transplantation into two adults includes: donor age > 3 years, donor weight > 12kg,…
  • 2017 American Transplant Congress

    Comparison of the Estimated and Measured Glomerular Filtration Rate in Kidney Donor Candidates.

    C. Akhimiona, W. Suki, D. Nguyen, E. Graviss.

    Nephrology, Houston Methodist Hospital, Houston, TX

    Background and objectivesThe assessment of GFR in kidney donor candidates is necessary for the appropriate allocation of donor kidneys to recipients. This assessment can be…
  • 2017 American Transplant Congress

    Prospective Monitoring of 25-Hydroxyvitamin Vitamin D Levels After Kidney Transplantation and Its Associations with Clinical Outcomes.

    P. Bedi, N. Hayde, L. Kamal, M. Ajaimy, M. Lubetzky, G. de Boccardo, E. Akalin.

    Montefiore Transplant Center, Albert Einstein College of Medicine, Bronx, NY

    Background: Kidney transplant recipients usually have low vitamin D levels. Vitamin D deficiency is recognized as a risk factor for progression of kidney disease in…
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