2017 American Transplant Congress
Influence of Donor-Specific Antibodies on Renal Function in Kidney Transplant Recipients Following Early Switch from Calcineurin Inhibitor to Everolimus: Subanalysis from the ELEVATE Study.
1ELEVATE Study Group, Llobregat Catalunya, Spain; 2Novartis Pharma AG, Basel, Switzerland
Purpose: The development of donor-specific antibody (DSA) is a known risk factor for poor graft outcomes after kidney transplantation (KTx). Previous analysis of the ELEVATE…2017 American Transplant Congress
Impact of Cognitive Impairment on Kidney Transplantation Listing Between Sexes.
1Surgery, JHU, Baltimore; 2Epidemiology, JHU, Baltimore
Cognitive impairment (CI) is common in end-stage renal disease (ESRD) patients and is associated with greater mortality. Despite this, cognitive function is not routinely measured…2017 American Transplant Congress
The Unfunded OPTN/UNOS Mandate of Living Kidney Donor Follow-Up: Fewer Than 50% of Centers in Compliance.
Surgery, Johns Hopkins, Baltimore, MD
OPTN/UNOS began requiring 2-year living donor follow-up (LDF) in 2013. Current LDF, and changes associated with the new guidelines, have not been evaluated.METHODS: Using SRTR…2017 American Transplant Congress
One-Year Graft and Patient Survival of Deceased Donor Kidney Transplants Under KAS.
Background: The new kidney allocation system (KAS) was implemented on 12/4/14 and led to more transplants for highly sensitized and long-term dialysis patients. Clinical characteristics…2017 American Transplant Congress
Effect of Academic Detailing with Prescribers as an Antimicrobial Stewardship Intervention in Solid Organ Transplant Patients.
1University Health Network, Toronto, ON, Canada; 2Sinai Health System, Toronto, ON, Canada
IntroductionThe role of academic detailing (AD) as an antimicrobial stewardship intervention, where the steward meets the prescribers in their practice setting to provide personal educational…2017 American Transplant Congress
Belatacept After Kidney Transplantation in Adolescents.
Pediatric Nephrology, Hannover Medical School, Hannover, Germany
Background: Regardless of recipient age at kidney transplantation (KTx), patients are at greatest risk for graft loss in adolescence. This is in part due to…2017 American Transplant Congress
Outcomes with Steroid Avoidance Regimen After Kidney Transplantation without Induction Immunosuppression.
INTRODUCTION: Use of induction immunosuppression therapy at the time of kidney transplantation is variable in low immunological risk kidney transplant recipients. Though acceptable allograft outcomes…2017 American Transplant Congress
IL-21R Antagonist Inhibits Differentiation of B Cells Towards Plasmablasts upon Alloantigen Stimulation.
Background: Antigen-specific antibody responses rely on IL-21+ T follicular helper (Tfh) cells that regulate B cell differentiation. In transplantation, a large proportion of renal allograft…2017 American Transplant Congress
Determinants of Severe Interstitial Fibrosis in Kidney Allografts: Major Impact of Circulating Donor-Specific Anti-HLA Antibodies.
Paris Translational Research Center for Organ Transplantation, Paris, France
Interstitial fibrosis represents a major cause of kidney allograft failure. We investigated the independent contribution of circulating donor-specific anti-HLA antibodies (DSA) in the development of…2017 American Transplant Congress
Chronic Antibody Mediated Rejection (cABMR) in ABO-Incompatible and ABO-Compatible Kidney Transplants: A Single US Center Experience.
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
Introduction:Similar patient and graft outcomes have been previously reported for ABO compatible (ABOc) and ABO incompatible (ABOi) kidney transplants. However, data are limited on the…
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