Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Delta Changes in Donor-Derived Cell-Free DNA (dd-cfDNA) Complement the Donor Fraction in Kidney Transplant Surveillance
A. Wiseman¹, M. Jagadeesan², G. Gupta³, V. Rao⁴, M. Narayanan⁵, N. Agrawal⁶, G. Shekhtman⁶, Y. Fu⁶, K. Pinney⁶, S. Anand⁷
¹Centura Health, Denver, CO, ²George Washington University, Washington, DC, ³Virginia Commonwealth University, Richmond, VA, ⁴Medical University of South Carolina, Charleston, SC, ⁵Baylor Scott and White, Austin, TX, ⁶CareDx, Brisbane, CA, ⁷Intermountain Healthcare, Murray, UT
*Purpose: Delta changes in dd-cfDNA levels over time may identify patients with evolving alloimmune injury, providing complementary information to the donor fraction. We explored the…
2022 American Transplant Congress
Association Between CT Measurements of Body Composition Before Kidney Transplantation and Post-Transplantation Outcomes
Y. Liu, O. Shafaat, X. Chen, C. Weiss, D. Segev, M. McAdams-DeMarco
Johns Hopkins University, Baltimore, MD
*Purpose: Body composition has been found to be associated with the risks of post-kidney transplantation (KT) outcomes. However, it is unclear which pre-KT computed tomography…
2022 American Transplant Congress
Non-White and Low-Socioeconomic Status Patients Are Less Likely to Present for Preemptive Kidney Transplant Evaluation: An Assessment of Referrals at a Single Center Serving a Diverse Urban Population
T. Menser, M. J. Hobeika, E. Hsu, L. W. Moore, A. D. Waterman, A. O. Gaber, R. J. Knight
Houston Methodist, Houston, TX
*Purpose: While preemptive kidney transplantation is the optimal renal replacement therapy for patients with end-stage kidney disease (ESKD), low rates of preemptive transplant, particularly for…
2022 American Transplant Congress
Interleukin-31 (IL-31) and Leukemia Inhibitory Factor (LIF) Are Upregulated in Acute Rejection of Kidney Allograft
I. Striz, L. Krupickova, M. Fialova, M. Novotny, E. Cecrdlova, O. Viklicky
Institute for Clinical and Experimental Medicine, Praha, Czech Republic
*Purpose: Interleukin-31 (IL-31) and leukemia inhibitory factor (LIF) belong to the IL-6 cytokine family clustered by their pro-inflammatory properties and a shared signaling pathway of…
2022 American Transplant Congress
Factors Influencing Access to Kidney Transplantation (FIAT): An Integrative Multiphasic Stakeholders’ Perspective
R. v. Merweland¹, A. Luchtenburg¹, J. van Busschbach¹, J. van de Wetering¹, S. Ismail²
¹Medical Psychology, Erasmus MC, Rotterdam, Netherlands, ²Erasmus MC, Rotterdam, Netherlands
*Purpose: Despite that various barriers to optimal access to transplantation are described in literature,there is no research combining the perspectives of all stakeholders in renal…
2022 American Transplant Congress
Kidney Transplant Professionals’, Recipients’ and Caregivers’ Perspectives on the Use of Precision Medicine in Kidney Transplantation
F. Ballesteros Gallego¹, A. Affdal¹, M. Malo², R. Sapir-Pichhadze³, M. Fortin¹
¹CRCHUM, Montreal, QC, Canada, ²University of Montreal, Montreal, QC, Canada, ³McGill University, Montreal, QC, Canada
*Purpose: Kidney transplantation is the optimal treatment for end-stage kidney disease. However, antibody-mediated rejection can lead to graft loss. The use of Precision Medicine (PM)…
2022 American Transplant Congress
Single-cell Transcriptomic Analysis Of Peripheral Blood Reveals The Disparate Subsets Of Innate Immune Cells In Kidney Transplant Recipient With BK Virus Infection
H. BAE¹, J. Ryu², J. Jang¹, J. Lee¹, G. Ko¹, H. PARK¹, E. Oh³
¹Department of Biomedical Science, Graduate School, College of medicine, The Catholic university of Korea, Seoul, Seoul, Korea, Republic of, ²Department of Laboratory Medicine, College of Medicine, Seoul St. Mary’s hospital, the Catholic University of Korea, seoul, Korea, Republic of, ³Catholic University Department of Laboratory Medicine, Seoul 137-040, Korea, Republic of
*Purpose: BK virus (BKV) infection is a common problem in kidney transplant recipients receiving immunosuppressive therapy, resulting in a serious complications including BKV-associated nephropathy and…
2022 American Transplant Congress
Single Nuclei RNA-Sequencing Identifies Distinct Immune Cell Profile in Kidney Allograft Fibrosis
J. McDaniels¹, A. Shetty¹, C. Kuscu², C. Kuscu², T. Rousselle¹, E. Bardhi¹, C. Drachenberg¹, M. Talwar², J. Eason², T. Muthukumar³, D. Maluf¹, V. Mas¹
¹University of Maryland Baltimore, Baltimore, MD, ²UTHSC, Memphis, TN, ³Weill Cornell Medicine, New York, NY
*Purpose: A major obstacle after kidney transplantation (KT) is chronic allograft dysfunction characterized by interstitial fibrosis and tubular atrophy (IFTA). Despite extensive research, the cellular…
2022 American Transplant Congress
Sirolimus Regimens After Kidney Transplantation: Role of Pre-Transplant Risk Factors in Modifying the Risk of Mortality in Adult Recipients
A. Santos¹, H. Ibrahim¹, M. A. Leghrouz¹, X. Wen²
¹University of Florida, Gainesville, FL, ²University of Rhode Island, Kinston, RI
*Purpose: We aimed to investigate the role of risk factors in modifying the association of sirolimus with mortality in kidney transplant (KT) recipients (KTRs).*Methods: Using…
2022 American Transplant Congress
Outcomes Following Renal Transplant with Hepatitis C Viremic Donors in an Elderly Veteran Population with Preemptive Mayvret Therapy
R. Lopez-Soler¹, A. Thorndyke¹, C. Trotter¹, A. Abadier², M. Samra¹
¹Surgery, Transplantation, Edward Hines Jr. Veterans Administration Hospital, Hines, IL, ²Surgery, Loyola University School of Medicine, Maywood, IL
*Purpose: Overall mortality on the kidney transplant waiting list is higher for older diabetic patients. The average age of waitlisted veteran patients is 64, with…