Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Performance of 2021 Creatinine and Cystatin C Based Equations without Race in Living Kidney Transplant Donors
A. Liaqat, H. Sawaf, L. Cholin, S. Arrigain, A. Wee, J. Schold, J. Augustine, E. Poggio
Cleveland Clinic, Cleveland, OH
*Purpose: New 2021 Creatinine (Cr) and Cystatin C (CysC) based GFR equations without the race factor have been refitted to perform better than either 2009…
2022 American Transplant Congress
Predicted Performance of Bayesian-Based Precision Dosing Software for Tacrolimus
A. Seghezzo¹, J. Kerr¹, A. Gupta², A. Ta², L. Powell², A. Feist³
¹University of California San Diego Health, San Diego, CA, ²PrecisePK, San Diego, CA, ³UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA
*Purpose: Bayesian-based precision dosing software (BPDS) has been utilized for therapeutic drug monitoring to optimize medication use. However, BPDS for tacrolimus (TAC) is not routinely…
2022 American Transplant Congress
Association of Trugraf GEP with Clinical and Histological Outcomes in a Multicenter Cohort (TOGETHER Study)
R. Heilman¹, W. Park², M. Mai³, B. Smith², R. First⁴, J. Fleming⁴, P. West-Thielke⁴, J. Holman⁴, M. Stegall²
¹Mayo Clinic, Phoenix, AZ, ²Mayo Clinic, Rochester, MN, ³Mayo Clinic, Jacksonville, FL, ⁴Transplant Genomics, Framingham, MA
*Purpose: The purpose of this study was to validate the association of TruGraf GEP with clinical endpoints in a real-world cohort.*Methods: This was a multicenter…
2022 American Transplant Congress
Expanding Access to Robotic Kidney Transplantation for Candidates with High BMI. A Training Tool for Transplant Centers
J. A. Almario Alvarez, G. Aguiluz, V. Valle, R. Bustos, S. Akshelyan, A. M. Fratti, P. D. Cocco, M. Spaggiari, I. G. Tzvetanov, E. Benedetti
Surgery, University of Illinois at Chicago, Chicago, IL
*Purpose: Recently published literature has demonstrated favorable outcomes for Robotic Kidney Transplant (RKT) in high BMI recipients. The University of Illinois at Chicago (UIC) has…
2022 American Transplant Congress
Evaluating the Risk and Benefit of Once Daily Delayed Release Mycophenolate in Pediatric Kidney Transplant Recipients
L. Maestretti¹, A. McGrath¹, A. Fong¹, A. Brubaker², A. Gallo³, P. Grimm³, A. Chaudhuri³
¹Pediatric Kidney Transplant, Stanford Children's Health, Palo Alto, CA, ²Transplant Surgery, Stanford University, Palo Alto, CA, ³Stanford University, Palo Alto, CA
*Purpose: Medication non-adherence continues to particularly affect adolescent kidney transplant recipients. Standard immunosuppressive regimen at our center includes tacrolimus, and mycophenolate with or without steroids.…
2022 American Transplant Congress
Delta Changes in Donor-Derived Cell-Free DNA (dd-cfDNA) Complement the Donor Fraction in Kidney Transplant Surveillance
A. Wiseman¹, M. Jagadeesan², G. Gupta³, V. Rao⁴, M. Narayanan⁵, N. Agrawal⁶, G. Shekhtman⁶, Y. Fu⁶, K. Pinney⁶, S. Anand⁷
¹Centura Health, Denver, CO, ²George Washington University, Washington, DC, ³Virginia Commonwealth University, Richmond, VA, ⁴Medical University of South Carolina, Charleston, SC, ⁵Baylor Scott and White, Austin, TX, ⁶CareDx, Brisbane, CA, ⁷Intermountain Healthcare, Murray, UT
*Purpose: Delta changes in dd-cfDNA levels over time may identify patients with evolving alloimmune injury, providing complementary information to the donor fraction. We explored the…
2022 American Transplant Congress
Association Between CT Measurements of Body Composition Before Kidney Transplantation and Post-Transplantation Outcomes
Y. Liu, O. Shafaat, X. Chen, C. Weiss, D. Segev, M. McAdams-DeMarco
Johns Hopkins University, Baltimore, MD
*Purpose: Body composition has been found to be associated with the risks of post-kidney transplantation (KT) outcomes. However, it is unclear which pre-KT computed tomography…
2022 American Transplant Congress
Non-White and Low-Socioeconomic Status Patients Are Less Likely to Present for Preemptive Kidney Transplant Evaluation: An Assessment of Referrals at a Single Center Serving a Diverse Urban Population
T. Menser, M. J. Hobeika, E. Hsu, L. W. Moore, A. D. Waterman, A. O. Gaber, R. J. Knight
Houston Methodist, Houston, TX
*Purpose: While preemptive kidney transplantation is the optimal renal replacement therapy for patients with end-stage kidney disease (ESKD), low rates of preemptive transplant, particularly for…
2022 American Transplant Congress
Interleukin-31 (IL-31) and Leukemia Inhibitory Factor (LIF) Are Upregulated in Acute Rejection of Kidney Allograft
I. Striz, L. Krupickova, M. Fialova, M. Novotny, E. Cecrdlova, O. Viklicky
Institute for Clinical and Experimental Medicine, Praha, Czech Republic
*Purpose: Interleukin-31 (IL-31) and leukemia inhibitory factor (LIF) belong to the IL-6 cytokine family clustered by their pro-inflammatory properties and a shared signaling pathway of…
2022 American Transplant Congress
Factors Influencing Access to Kidney Transplantation (FIAT): An Integrative Multiphasic Stakeholders’ Perspective
R. v. Merweland¹, A. Luchtenburg¹, J. van Busschbach¹, J. van de Wetering¹, S. Ismail²
¹Medical Psychology, Erasmus MC, Rotterdam, Netherlands, ²Erasmus MC, Rotterdam, Netherlands
*Purpose: Despite that various barriers to optimal access to transplantation are described in literature,there is no research combining the perspectives of all stakeholders in renal…