Articles tagged "Kidney transplantation"

2018 American Transplant Congress
The Combination of Area under Curve of Estimated Glomerular Filtration Rate for 2 Years and Annual Rate Change of Estimated Glomerular Filtration Rate Predicts Long-Term Graft Survival in Kidney Transplants
E. Lee,¹ J. Jeon,¹ S. Kim,¹ M. Kim,¹ K. Lee,¹ H. Jang,¹ J. Lee,¹ J. Hwang,² D. Kim,¹ Y-.G. Kim,¹ H. Oh,¹ W. Huh,¹ J. Kim.³
¹Department of Medicine, Samsung Medical Center, Seoul, Republic of Korea; ²Department of Anesthesiology and Pain Medicine, Seoul National University BunDang Hospital, Sungnam, Republic of Korea; ³Department of Surgery, Samsung Medical Center, Seoul, Republic of Korea.
Improvement of short-term outcomes in kidney transplant (KT) has required clinical trials to evaluate long-term hard outcomes for validation of new therapies. However, because of…
2018 American Transplant Congress
Elevated Donor Terminal Creatinine Does Not Appear to Be Associated with Worse Outcomes in Kidney Transplantation
S. Rayhill, J. Haldorson.
U Washington, Seattly.
There is justified reluctance to use kidneys from donors with significantly elevated creatinine as they may have severe, irreversible injury. Recently, thanks, in part to…
2018 American Transplant Congress
Multi-Drug Resistant Urinary Tract Infections Following Renal Transplant: Risk Factors and Patient Outcomes
D. Hooker,¹ K. Gutierrez,² K. Foster,¹ A. Dodson.²
¹Samford University McWhorter School of Pharmacy, Birmingham, AL; ²Comprehensive Transplant Institute, UAB Hospital, Birmingham, AL.
Background: Urinary tract infections (UTIs) are the most common infection after kidney transplant (KTx) resulting in significant morbidity and mortality. The reported incidence of UTIs…
2018 American Transplant Congress
Reduced Ratio of FoxP3/ RORγt Gene Expression, in Peripheral Blood, is Associated with Acute Allograft Rejection in Recipients with Kidney Transplantation
R. Dhital,^1,2 R. Minz,³ M. Minz,^1,4 A. Sharma,¹ R. Nada,⁵ S. Singh,¹ D. Kenwar,¹ S. Anand.³
¹Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, UT, India; ²Vaccines and Immunity, Nationwide Children's Hospital, Columbus, OH; ³Immunopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, UT, India; ⁴Organ Transplantation, Fortis Hospital, Mohali, Punjab, India; ⁵Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, UT, India.
Introduction:FoxP3 has been well established as an indispensable protein that is required in the development and function of regulatory T cells. On the other hand,…
2018 American Transplant Congress
Identifying Patients with CPRA>99.95% Likely to Be Offered Deceased Donor Kidneys
R. Parsons, S. Bumb, H. Decker, R. Bray, H. Gebel.
Emory Transplant Center, Atlanta, GA.
The implementation of the new kidney allocation system and priority of kidneys for cPRA=100% subjects revealed a hierarchy difference in allocation to patients with cPRA=99.45%-100%.…
2018 American Transplant Congress
Is KDPI Valid for Hepatitis C Aviremic Kidneys?
L. Sibulesky,¹ C. Kling,¹ C. Blosser,² C. Johnson,² A. Limaye,² R. Bakthavatsalam,¹ N. Leca,² J. Perkins.¹
¹Surgery, University of Washington Medical Center, Seattle, WA; ²Medicine, University of Washington Medical Center, Seattle, WA.
KDRI is an estimate of post-transplant kidney graft failure. It is based on ten donor factors that independently affect transplant outcomes, including HCV status from…
2018 American Transplant Congress
Potential Living Donors Identified through Social Media
S. Weeks, K. Kumar, J. Konel, E. King, M. Henderson, A. Cameron, J. Garonzik Wang.
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD.
Purpose: We previously described a smartphone application that harnesses social media to increase potential living donors among kidney and liver transplant candidates. We compared potential…
2018 American Transplant Congress
Transplanting Kidneys from HCV-Infected Donors into HCV-Negative Recipients: Longer-Term and Extended Results of the THINKER Trial
D. Goldberg,¹ E. Blumberg,¹ P. Abt,¹ M. Levine,¹ P. Porrett,¹ A. Naji,¹ S. Nazarian,¹ D. Sawinski,¹ J. Trofe-Clark,¹ V. Van Deerlin,¹ C. Gentile,¹ J. Smith,¹ M. Kaminski,¹ A. Sicilia,¹ R. Hasz,² L. Suplee,² R. Reddy,¹ R. Bloom,¹ P. Reese.¹
¹University of Pennsylvania, Philadelphia; ²Gift of Life, Philadelphia.
Background: In 2016, 800 kidneys from HCV+ deceased donors were discarded. Short-term (6-month) data from the first 10 subjects in the THINKER-1 trial (NCT02743897; funder:…
2018 American Transplant Congress
Disparity in Access to Kidney Allograft Offers among HIV+ Transplant Candidates
J. Cohen,¹ J. Locke,² B. Shelton,² R. Reed,² P. MacLennan,² D. Sawinski.¹
¹Renal Division, University of Pennsylvania, Philadelphia, PA; ²Comprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.
Background: Despite having a demonstrated survival benefit with kidney transplantation, patients with chronic viral infections, such as HCV or HIV, face many barriers to transplantation,…
2018 American Transplant Congress
Comparing Outcomes between Induction Immunosuppressive Therapies in Simultaneous Heart/Kidney Transplantation
I. Moinuddin, J. Yu, L. Kang, C. Bhati, D. Bandyopadhyay, A. King, D. Kumar, L. Kamal, D. Tang, I. Yakubu, G. Gupta.
Virginia Commonwealth University, Richmond.
Introduction: There is no published data on the risks and benefits of Induction immunosuppression in simultaneous heart/kidney transplant (SHKT) patients.Methods: We analyzed all SHKT performed…