Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Developing a Rationale for an Appropriate Immunosuppressive Regimen in Lung vs Kidney Transplant Recipients: Effects of Induction Therapy
P. Martin-Moreno,^1,2 H. Shin,^1,3 H. Goldberg,⁴ A. Chandraker.¹
¹Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; ²Nephrology Department, Clinica Universidad de Navarra, Pamplona, Spain; ³Renal Division, Department of Internal Medicine, Gospel Hospital, Kosin University College of Medicine, Busan, Korea; ⁴Pulmonary Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
IntroductionThe appropriate use of Thymoglobulin (ATG) or Basiliximab as induction therapy is not fully understood. We studied circulating cytokine profiles following kidney and lung transplantation…
2018 American Transplant Congress
Does the End Justify the Means? An Analysis of Outcomes in Recipients of Combined Kidney/Hematopoietic Stem Cell (HSC) Transplants and Comparison to Standard of Care (SOC) Patients
J. Leventhal,¹ A. Shetty,¹ L. Gallon,¹ K. Kurtenbach,¹ D. Stare,¹ S. Ildstad.²
¹Northwestern U, Chicago; ²U Louisville, Louisville.
Eliminating the long term costs and side effects of immunosuppression (IS) is a compelling reason to pursue transplant tolerance. Tolerance in kidney transplant (KTx) pts…
2018 American Transplant Congress
The Internet as a Source of Transplant-Related Information for New Kidney Transplant Candidates
W. Fu, N. Chai, P. Yoo.
Surgery, Yale School of Medicine, New Haven, CT.
Background: Studies of Internet usage show that a large proportion of Americans turn to the Internet as a source of health information, with many reporting…
2018 American Transplant Congress
High Tacrolimus Variability is Associated with Worse Outcomes in Pediatric Renal Transplant Recipients
S. Solomon, M. Del Rio, A. Colovai, N. Hayde.
Montefiore Medical Center, Bronx, NY.
Background: Subtherapeutic tacrolimus trough concentrations are associated with donor specific antibody (DSA), acute rejection and shortened graft survival. The role of intrapatient variability in tacrolimus…
2018 American Transplant Congress
Protocol Biopsies after Paediatric Kidney Transplantation: A Single Centres' 17 Year Experience
T. Alsulaimi,¹ M. Aloufi,² S. Grisaru,¹ S. Samuel,¹ L. Hamiwka.¹
¹Paediatric Nephrology, University of Calgary, Calgary, AB, Canada; ²Pediatric Nephrology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
PURPOSE: Standard laboratory measures are not sensitive indicators of kidney dysfunction following transplantation and may be less reliable in paediatric recipients. Early graft surveillance may…
2018 American Transplant Congress
The Effect of Pre-Transplant Insomnia and Post-Transplant Insomnia on Survival among Solid Organ Recipients
K-.F. Lee,² Y. Tsai,¹ C. Lin,¹ C-.B. Hsieh,^3,5 S. Wu,⁴ T. Chen,⁵ Y-.C. Lin,¹ W-.H. Lee,^6,7 F. Lin,⁸ C. Tsai.^1,9,10
¹Cardiovascular Surgery, Tri-Service General Hospital, Taipei, Taiwan; ²Biobank Management Center, Tri-Service General Hospital, Taipei, Taiwan; ³General Surgery, Hualien Armed Forces General Hospital, Hualien County, Taiwan; ⁴Urology, Tri-Service General Hospital, Taipei, Taiwan; ⁵General Surgery, Tri-Service General Hospital, Taipei, Taiwan; ⁶Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; ⁷Pathology, Taipei Medical University-Shuang Ho Hospital, New Taipei, Taiwan; ⁸Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; ⁹Cardiovascular Surgery, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan; ¹⁰Graduate Institute of Pharmacology, National Defense Medical Center, Taipei, Taiwan.
BackgroundBecause studies about insomnia among organ recipients were scarce, we used National Health Insurance Research Database (NHIRD) between 2001 and 2012 to understand how pre-transplant…
2018 American Transplant Congress
Sub-Clinical Acute Rejection (subAR) Detected by Both Surveillance Biopsy (SBx) and a Peripheral Blood Molecular Biomarker Correlates with De Novo Donor Specific Antibody (dnDSA) Following Kidney Transplant (KT)
R. Heilman,¹ J. Friedewald,² K. Kurian,⁵ T. Whisemant,⁵ E. Poggio,³ C. Marsh,⁵ P. Baliga,⁷ N. Bridges,⁴ J. Odim,⁴ M. Brown,⁴ D. Ikle,³ B. Armstrong,³ L. Zhao,² D. Salomon,⁵ M. Abecassis.²
¹Mayo Clinic, Phoenix; ²Northwestern University, Chicago; ³Rho Federal Systems, Chapel Hill; ⁴National Institute of Allergy and Infectious Disease, Bethesda; ⁵Scripps Health, La Jolla; ⁶Cleveland Clinic, Cleveland; ⁷Medical University of South Carolina, Charleston.
AIMWe investigated the correlation between subAR diagnosed by SBx or by a newly-defined biomarker, and the development of dnDSA.METHODS307 KT patients enrolled into a multi-center…
2018 American Transplant Congress
Patients Prioritize Waitlist Factors over Outcomes When Evaluating Kidney Transplant Centers
A. Michelson, C. Brennan, A. Mattoo, B. Kil, D. Tsapepas, S. Husain, S. Mohan.
Nephrology, Columbia University Medical Center, New York, NY.
The factors that influence transplant candidates' selection of a transplant center for waitlisting are not well understood. Further, the relative weightage of these factors has…
2018 American Transplant Congress
Late Conversion from Calcineurin Inhibitors to Belatacept is Associated with a Sustained Improvement in Kidney Allograft Function
S. Sethi, J. Choi, A. Vo, R. Najjar, A. Peng, S. Jordan, E. Huang.
Medicine/Nephrology, Cedars Sinai Medical Center, Los Angeles, CA.
Introduction: Belatacept was shown to have longer kidney graft survival and higher eGFR at 7 years than a calcineurin inhibitor (CNI)-based regimen in the BENEFIT…
2018 American Transplant Congress
Cognition after Belatacept Conversion
C. Ogbejesi, E. Cohen, K. Belfield, W. Asch.
Yale University, New Haven, CT.
Intro: Kidney Transplant Recipients (KTRs) taking calcineurin inhibitors (CNIs) can experience varying drug toxicities. Less well studied compared to the metabolic consequences, many patients report…