Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Once Daily CNI Administration Based on Pharmacodynamic Analysis for Preventing Viral Infection
Y. Matsuoka,¹ K. Iwasaki,² Y. Miwa,² K. Horimi,¹ K. Uchida,² T. Kobayashi.¹
¹Renal Transplant Surgery, Aichi Medical University, Nagakute City, Aichi, Japan; ²Kidney Disease and Transplant Immunology, Aichi Medical University, Nagakute City, Aichi, Japan.
BackgroundInfectious complications under immunosuppressive therapy are inevitable problems. Viral infection (include reactivation) occurs at a certain frequency even if immunosuppressive agents are totally adjusted by…
2018 American Transplant Congress
β-Glucuronidase Gene Expression in Stool Samples Associated with Chronic Allograft Dysfunction in Kidney Transplants
A. Israni,^1,2 D. Knights,³ G. Al-Ghalith,³ A. Muthusamy,² B. Wu,⁴ W. Oetting,⁵ D. Schaldt,² R. Remmel,⁵ P. Jacobson,⁵ For DeKAF Genomics & GEN03 Investigators.¹
¹Medicine, HCMC, University of MN (UMN), Minneapolis; ²Minneapolis Medical Research Foundation (MMRF), Mpls; ³Computer Science, UMN, Mpls; ⁴Biostatistics, UMN, Mpls; ⁵College of Pharmacy, UMN, Mpls.
Background: Myocophenolate mofetil (MMF) is a prodrug that is extensively and rapidly converted to the active component, mycophenolic acid (MPA). MPA undergoes extensive enterohepatic recycling…
2018 American Transplant Congress
Attitudes of African Canadian Patients with End Stage Kidney Disease toward Living Donor Kidney Transplantation
V. Gupta, C. Richardson, D. Belenko, N. Singh, A. Xu, P. Thiagalingam, D. Wong, H. Ford, M. Novak, I. Mucsi.
University Health Network, Toronto, ON, Canada.
Background:African Canadian patients with end stage kidney disease (ESKD) are less likely to receive a living donor kidney transplant (LDKT) compared to Caucasian Canadians. We…
2018 American Transplant Congress
Prediction of 90 Days Readmission after Kidney Transplantation Including Natural Language Processing
X. Zhang,¹ M. Arenson,⁴ J. Kim,⁴ G. Karadkhele,¹ J. Hogan,^1,5 Y. Zhang,⁶ A. Adams,¹ R. Patzer.^1,2,3
¹Department of Surgery, Emory University, Atlanta; ²Department of Epidemiology, Emory University, Atlanta; ³Emory Transplant Center, Emory Healthcare, Atlanta; ⁴School of Medicine, Emory University, Atlanta; ⁵Department of Pediatrics, Emory University, Atlanta; ⁶Rollins School of Public Health, Emory University, Atlanta.
Early identification of hospital readmission for End Stage Renal Disease (ESRD) patients who obtained kidney transplantation potentially help decrease their risk of readmission after transplantation,…
2018 American Transplant Congress
HLA Mismatching and cPRA Do Not Affect BK Viremia and Nephropathy Risk in Kidney Transplantation: A Retrospective Analysis
B. Suleiman, S. Saleh, W. Hassan, K. Wang, A. Maibam, A. Karim, A. Hines, X. Mei, A. El-Husseini, M. Yaseen, V. Cornea, A. Castellanos, R. Gedaly, T. Waid.
Nephrology, University of Kentucky, Lexington, KY.
Introduction:Nephropathy from BK virus is a significant complication of kidney transplantation and occurs following a period of viremia. Patients who are HLA mismatched and more…
2018 American Transplant Congress
Analyzing Transplant Medication Myths
R. Krislock, J. Brandenberger, P. Stracener, A. Weiss, K. Wipperling, C. Kuhr.
Division of Transplant, Virginia Mason Medical Center, Seattle, WA.
Patients may misconstrue the amount of medications required for transplantation, expecting to take “handfuls” of medications for life. This study aims to determine the change…
2018 American Transplant Congress
Comparison of Temperatures for Optimal Preservation of Donor Kidneys during Oxygenated Pulsatile Perfusion
R. Bhattacharjee,¹ M. Richard-Mohamed,² A. Ruthirakanthan,³ R. Mayer,² S. Luke,³ H. Sharma,² M. TunAbraham,² B. Alharbi,² A. Haig,² P. Luke.^1,2,3
¹Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada; ²Multi-Organ Transplant Program, London Health Sciences Centre, London, ON, Canada; ³Western University, Canada, London, ON, Canada.
Background. The current methods of preserving DCD renal allografts in either static cold solution or hypothermic pulsatile perfusion are unable to adequately protect the kidney…
2018 American Transplant Congress
Donor Specific Antibodies Increase the Risk of Preeclampsia in Pregnant Kidney Transplant Recipients
M. Lubetzky, T. Muthukumar, J. Lee, J. Lee, C. Hartono, L. Mahla, D. Serur, D. Dadhania.
Weill Cornell-New York Presbyterian, NY, NY.
Kidney transplant recipients are at an increased risk for pregnancy-associated complications including preeclampsia (PEC). Endothelial injury in the placenta is a hallmark of PEC. The…
2018 American Transplant Congress
The Value of Serum Dilution on DSA Outcome Analysis in Renal Transplantation
W. Huang,¹ L. Rebellato,² K. Briley,² P. Bolin,² S. Kendrick,³ A. Maldonado,⁴ D. Leeser,² C. Haisch,² M. Everly.¹
¹Terasaki Research Institute, Los Angeles, CA; ²East Carolina University, Greenville, NC; ³Eastern Nephrology Associates, Greenville, NC; ⁴Vidant Medical Center, Greenville, NC.
Background: Recently, transplant centers have discussed the potential value of sera dilutions in assessment of donor specific anti-HLA antibodies (DSA). However, to date, no data…
2018 American Transplant Congress
Successful Utilization of Deceased Donor Kidney Allografts with KDPI>85: The Organ is Not Wholly to Blame
A. Agarwal,¹ A. Nishio Lucar,² A. Nickkholgh,¹ K. Brayman,¹ A. Doyle,² J. Oberholzer.¹
¹Dept. of Surgery, University of Virginia Health System, Charlottesville, VA; ²Dept. of Internal Medicine, University of Virginia Health System, Charlottesville, VA.
Background: High kidney donor profile index (KDPI)>85% organs are increasingly discarded, suggesting missed opportunities to provide patients the benefits of transplantation. Herein, we report the…