Articles tagged "Kidney transplantation"

2018 American Transplant Congress
BLyS^-/- Rats to Prevent Alloantibody Production
N. Bath,¹ B. Verhoven,¹ N. Wilson,¹ S. Reese,² L. Coons,¹ S. Panzer,² A. Djamali,² R. Redfield.¹
¹Surgery, University of Wisconsin, Madison, WI; ²Medicine, University of Wisconsin, Madison, WI.
Introduction: Antibody mediated rejection (AMR) is a major cause of kidney allograft failure. APRIL (A Proliferation Inducing Ligand) and BLyS (B Lymphocyte Stimulator) are two…
2018 American Transplant Congress
The Prognostic Implications of Renal Function Recovery and Delayed Graft Function in Kidney Transplantation
S. Sandal, M. Cantarovich, A. Ramankumar, N. Saberi, C. Saw, D. Baran, P. Chaudhury, S. Paraskevas, J. Tchervenkov.
MUHC, Montreal, Canada.
Introduction: Lack of renal function recovery (RFR), 90 days after acute kidney injury (AKI) is a contributor to inferior renal outcomes and mortality. Ischemia and…
2018 American Transplant Congress
Change in Estimated Glomerular Filtration Rate Pre and Post Development of Donor-Specific Antibodies after Kidney Transplantation
B. Ho,¹ S. Montag,^1,2 H. Bhagat,³ K. Atiemo,¹ A. Daud,¹ R. Kang,¹ L. Zhao,^1,2 J. Schwartz,³ D. Ladner.¹
¹Northwestern University Transplant and Outcomes Research Collaborative (NUTORC), Chicago; ²Dept of Preventive Medicine, Northwestern University, Chicago; ³Astellas Pharma Global Development, Inc., Northbrook.
Formation of de novo donor-specific antibodies (dnDSA) against human leukocyte antigens contributes to inferior kidney transplant (KT) outcomes. We assessed the effect of dnDSA on…
2018 American Transplant Congress
Proton Pump Inhibitor Use among Kidney Transplant Recipients
N. Wilson, S. Bala, B. Concepcion.
Vanderbilt University Medical Center, Nashville, TN.
Background: Proton Pump Inhibitors (PPIs) have been associated with CKD and other serious adverse effects. PPI use in the transplant population has not been well-described.…
2018 American Transplant Congress
Peri-Operative Hemoglobin, Blood Transfusion and Delayed Graft Function in Kidney Transplant Recipients
S. MacIsaac, A. Ramankumar, C. Saw, V. Naessens, M. Cantarovich, D. Baran, S. Paraskevas, J. Tchervenkov, P. Chaudhury, S. Sandal.
MUHC, Montreal, Canada.
Background: Studies in the non-kidney transplant (KT) literature support an absolute hemoglobin concentration (Hb) threshold of 70 g/L for transfusion, unless otherwise indicated. Some reports…
2018 American Transplant Congress
Decision-Making, Informed Consent, and the Experiences of Recipients of Experimental HCV Positive-to-Negative Renal Transplants
S. Rasmussen, S. Seaman, D. Brown, N. Desai, M. Sulkowski, D. Segev, J. Sugarman, C. Durand.
JHU, Baltimore.
Background: The safety and efficacy of transplanting HCV-infected (HCV+) donor organs into HCV-uninfected recipients (HCV D+/R-) is being studied. Recipient experiences are essential to comprehensively…
2018 American Transplant Congress
Subclinical Borderline Rejection: More Than Meets the Eye?
M. Bernard, G. Agarwal, H. Fatima, B. Julian, C. Kew, V. Kumar, S. Mehta, S. Ong, A. Patel, G. Towns, M. Seifert, R. Mannon.
UAB School of Medicine, Birmingham.
Purpose: Surveillance biopsies can detect subclinical T cell mediated rejection (SC-TCMR) or subclinical borderline rejection (SC-B-TCMR) in patients with normal/stable creatinine, but the impact on…
2018 American Transplant Congress
Variation in Hypothermic Machine Perfusion Utilization and Clinical Outcomes for Deceased-Donor Kidneys
V. Krishnamoorthy,¹ S. Wunsch,² K. O'Connor,² M. Souter.³
¹Anesthesiology, Duke University, Durham, NC; ²LifeCenter Northwest, Bellevue, WA; ³Anesthesiology and Pain Medicine, University of Washington, Seattle, WA.
Introduction:Hypothermic machine perfusion (HMP) has been shown to be an effective method for preserving kidney allografts from deceased donors (1), but data suggests that low-risk…
2018 American Transplant Congress
Impact of the New Kidney Allocation System A2/A2B –> B Policy on Access to Transplantation among Minority Candidates
M. Mustian,¹ P. Martins,² P. MacLennan,¹ J. Ortiz,² J. Caicedo,² S. Gray,^1,2 B. Kelly,² C. Esquivel,² ASTS Diversity Affairs Commmittee,² J. Locke.^1,2
¹University of Alabama at Birmingham, Birmingham; ²ASTS Diversity Affairs Committee, Arlington.
Introduction: Blood group B kidney transplant candidates, many of whom represent ethnic minorities, have historically had diminished access to deceased donor kidney transplantation (DDKT). However,…
2018 American Transplant Congress
Landscape of Living Donor Kidney Transplantation with International Donors in the United States
A. Thomas,¹ M. Henderson,¹ A. Shaffer,¹ A. Massie,¹ B. Koons,² K. Lentine,³ D. Segev,¹ F. Al Ammary.¹
¹JHU, Baltimore; ²Villanova University, Villanova; ³SLU, St. Louis.
International living kidney donors (LKDs) can donate to candidates listed in the US. Recently, concerns were raised that international LKD organ-recipients might not achieve the…