Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Differences in Preservation Solution Formulas and Its Effects on Early Graft Function
J. Brooks, P. Wiederhold, K. Jiles, A. Chiodo Ortiz, M. Dewey, M. Bailey, N. Koizumi, E. Rady, J. Ortiz.
University of Toledo Medical Center, Toledo, OH; University of California-Los Angeles, Los Angeles, CA; Life Connection of Ohio, Maumee, OH; George Mason University, Fairfax, VA.
Introduction: Machine perfusion has proven benefits and is common practice among transplant centers. However, the formulas of preservation solutions vary between organ procurement organizations (OPOs).…
2018 American Transplant Congress
Urine Pellet Podocyte mRNAs Correlate Closely with Late Kidney Allograft Loss-of-Function
A. Naik,¹ J. Aqeel,¹ D. Cibrik,² M. Samaniego,¹ M. Chowdhury,¹ S. Wang,¹ F. Afshinnia,¹ R. Wiggins.¹
¹Univ Michigan, Ann Arbor; ²Univ Kansas, Kansas City.
10-year surveillance biopsy studies (Nankivell,2003 & Stegall,2017) and podometric studies are compatible with progressive glomerulosclerosis (GS) contributing to long-term allograft loss-of-function.Thus one would expect to…
2018 American Transplant Congress
Outcome Analysis of Renal Re-Transplantation Compared to a Matched Control Group of First Transplantation
A. Schwarz,¹ F. Schaefer,¹ T. Framke,² S. Linnenweber,¹ H. Haller.¹
¹Nephrology, Hannover Medical School, Hannover, Germany; ²Biostatistics, Hannover Medical School, Hannover, Germany.
Background: 15% of our renal transplant program is re-transplantation (Tx2). We aimed to know if Tx2 has a higher risk than first transplantation (Tx1) and…
2018 American Transplant Congress
New Factors Predicting Delayed Graft Function: A Multi-Center Cohort Study Based on Kidney Donation after Brain Death Followed by Circulatory Death
Q. Sun,¹ H. Zhou,² M. Lin,³ X. Hua,¹ L. Hong,¹ Z. Huang,¹ N. Na,¹ R. Cai,³ G. Wang,² Q. Sun.¹
¹The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; ²The First Affiliated Hospital, Jilin University, Changchun, China; ³The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Background. Delayed graft function (DGF) is a common complication following kidney transplantation that exerts an adverse impact on graft outcomes. Donation after brain death followed…
2018 American Transplant Congress
One-Year Outcomes in Patients with Advanced Liver Fibrosis or Compensated Cirrhosis from Chronic Hepatitis C Receiving Kidney Transplant Alone
P. Brown, F. Kumssa, D. Venkat.
Henry Ford Hospital, Detroit.
Background: Hepatitis C (HCV) was difficult to treat post-kidney transplant prior to the direct acting antiviral (DAA) era. As such patients with advanced fibrosis and…
2018 American Transplant Congress
Recipient Outcomes in Age Mismatched Living Kidney Transplants from Donors > 60 Years: A UNOS Database Analysis
O. Adebiyi, A. Riaz, M. Yaqub, D. Mishler, T. Taber, A. Sharfuddin.
Indiana University, Indianapolis.
Background: Donor and recipient age mismatch kidney transplantation are known to affect graft survival. We examined the impact of age mismatching on graft survival after…
2018 American Transplant Congress
Prostate Cancer Characteristics in Men on Immunosuppressive Medications
M. Eltemamy, A. Elshafei, A. Salah, Y. Nyame, H. Arora, A. Wee, V. Krishnamurthi, S. Jones.
Cleveland Clinic, Cleveland.
INTRODUCTION: To assess the prevalence of prostate cancer (PCa) in men receiving immunosuppressive medications undergoing transrectal ultrasound guided (TRUS) prostate biopsy.METHODS: A total of 468…
2018 American Transplant Congress
Polyclonal Cellular Immune Function is Dose-Dependently Inhibited by Immunosuppressive Drugs but Has Limited Value in Predicting Infection or Rejection Episodes
S. Marx,¹ C. Adam,² S. Leyking,² U. Sester,² M. Sester.
¹Saarland University, Homburg/Saar, Germany; ²Saarland University, Homburg/Saar, Germany.
Background: Dosage of immunosuppressive drugs in transplant patients must be balanced to prevent graft rejection and infectious complications. Knowledge on general immune function may therefore…
2018 American Transplant Congress
Inflammatory Frailty Index and Mortality after Kidney Transplantation
C. Haugen, H. Ying, M. McAdams-DeMarco, D. Segev.
Surgery, JHU, Baltimore.
Frailty is a phenotype of decreased physiologic reserve and is associated with a pro-inflammatory state. Fried frailty (slow walk speed, weight loss, decreased grip, low…
2018 American Transplant Congress
The THINKER Trial: Quality of Life Results at 6- and 12-Month Follow-Up among Hepatitis C-Negative Patients Who Received Kidney Transplants from Deceased Donors with Hepatitis C Infection
V. Potluri, D. Goldberg, A. Peter, B. Emily, B. Roy, S. Deirdre, M. Levine, J. Trofe-Clark, M. Bleicher, S. Goral, A. Sicilia, S. Nazarian, R. Reddy, P. Porrett, P. Reese.
Univ of Pennsylvania, Philadelphia, PA.
Background: Short-term (6-month) data from the first 10 subjects in the pilot THINKER-1 trial (NCT02743897; funder: Merck) suggested that kidneys from HCV-infected donors could be…