ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2018 American Transplant Congress

    Klotho Enhances FoxO3-Mediated Manganese Superoxide Dismutase Expression by Negatively Regulating PI3K/AKT Pathway during Tacrolimus-Induced Oxidative Stress

    S. Lim,1 K. Luo,1 J. Il,1 Y. Shin,1 E. Ko,1,2 B. Chung,1,2 C. Yang.1,2

    1Transplant Research Center, The Catholic University of Korea, Seoul, Republic of Korea; 2Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.

    Mammalian members of the forkhead box protein O (FoxO) class of transcription factors are implicated in the regulation of oxidative stress, and FoxO proteins are…
  • 2018 American Transplant Congress

    Impact of Aberrant Post-Transplant Laboratory and Blood Pressure Values on Graft Survival and Racial Disparities in Kidney Transplant

    D. Taber, Z. Su, J. Fleming, N. Pilch, A. Posadas, V. Rao, P. Mauldin, D. Dubay.

    MUSC, Charleston, SC.

    Objective: The aim of this study was to assess the impact of post-transplant lab and blood pressure (BP) clinical data on graft survival and racial…
  • 2018 American Transplant Congress

    Death-Censored Graft Failure (DCGF) Post Kidney Transplant (KTx) is Usually the Result of Rapid Loss of Function after Periods of Stability

    R. Gaston,1 L. Hunsicker,2 A. Fieberg,3 A. Matas,3 The DeKaf Consortium.

    1CTI Clinical Trial & Consulting, Covington, KY; 2Int. Med., U Iowa, Iowa City, IA; 3Biostatistics and Surgery, U Minnesota, Minneapolis, MN.

    Late graft dysfunction leading to clinically indicated transplant biopsy (KTxBx) is a better predictor of subsequent DCGF than baseline data and early post-transplant events (Gaston…
  • 2018 American Transplant Congress

    Outcomes of Very Old Kidney Recipients of Grafts from Very Old Donors

    H. Trujillo, A. García, T. Cavero, B. Redondo, C. Moliz, T. Bada, E. González, M. Praga, A. Andrés.

    Nephrology Department, Hospital Universitario 12 de Octubre, Madrid, Spain.

    Aims: Describe the outcomes of very old kidney recipients of grafts from very old donors. Identify pretransplant clinical factors associated with graft and recipient survival.Methods:…
  • 2018 American Transplant Congress

    The Impact of Induction Agent on Development of Febrile Neutropenia Following Kidney Transplant

    G. Dube, S. Husain, D. Cohen, S. Mohan.

    Medicine, Columbia University Medical Center, New York, NY.

    Neutropenia is common after kidney transplant (KT), usually due to medication side effects (induction agents maintenance medications, antibiotics), and is associated with worse patient and…
  • 2018 American Transplant Congress

    Technical Challenges in Living Donor Kidney Transplantation – Diagnosis and Solutions

    R. Öllinger,1 K. Alqasim,1 F. Klein,1 N. Raschzok,1 P. Ritschl,1 S. Chopra,1 N. Otto,2 T. Denecke,3 U. Gerlach,1 M. Schmelzle,1 P. Reinke,2 J. Pratschke.1

    1Department of Surgery, Charité, Berlin, Germany; 2Department of Nephrology, Charité, Berlin, Germany; 3Department of Radiology, Charité, Berlin, Germany.

    IntroductionDue to organ scarcity living donation is becoming a major source of kidneys for transplantation. Besides medical contraindications, anatomy of the kidneys may be a…
  • 2018 American Transplant Congress

    Diagnosis of Acute Renal Rejection Using Saliva Metabolome Analysis

    H. Iwamoto,1 M. Sugimoto,2 O. Konnno,1 Y. Kihara,1 T. Yokoyama,1 Y. Nakamura,1 M. Sunamura,1 T. Ueno.1

    1Kidney Transplantation Surgery, Tokyo Medical University, Hachioji, Tokyo, Japan; 2Health Promotion and Preemptive Medicine, Research and Development Center for Minimally Invasive and Preemptive Medicine, Tokyo Medical University, Hachioji, Japan; 3Department of Digestive Surgery and Transplantation Surgery, Tokyo Medical University, Hachioji, Tokyo, Japan.

    (Objective) Wide variety of biomarker discoveries have been conducted to realize low-invasive detection of rejection after renal transplantation. Metabolomics, an omics technology to enable simultaneous…
  • 2018 American Transplant Congress

    Is Kidney Transplantation Safe in Patients over 71 Years Old?

    G. Andani, P. Tulissi, M. Gropuzzo, S. Crestani, C. Vallone, U. Baccarani, D. Montanaro, A. Risaliti.

    Department of Kidney & Liver Transplantation, ASUIUD, Udine, Italy.

    Introduction: Kidney transplantation in elderly patients is superior over dialysis as therapy for end stage renal disease (ESRD). We analyzed different parameters to evaluate patient…
  • 2018 American Transplant Congress

    Five-Year Outcomes after Randomized Treatment by Rituximab in Early Acute Antibody-Mediated Rejection in Renal Transplantation: Long Term Outcomes of the RITUX ERAH Study

    E. Bailly,1 G. Blancho,2 S. Ville,2 E. Morelon,3 J. Bamoulid,4 S. Caillard,5 V. Chatelet,6 P. Malvezzi,7 J. Tourret,8 V. Vuiblet,9 D. Anglicheau,10 D. Bertrand,11 P. Grimbert,12 F. Haidar,13 M. Hazzan,14 N. Kamar,15 P. Merville,16 C. Mousson,17 V. Pernin,18 C. Pouteil-Noble,19 R. Purgus,20 J. Sayegh,21 P. Westeel,22 M. Büchler.1

    1University Hospital, Tours, France; 2Institut de Transplantation-Urologie-Néphrologie, Nantes, France; 3University Hospital, Lyon Edouard Herriot, France; 4University Hospital, Besançon, France; 5University Hospital, Strasbourg, France; 6University Hospital, Caen, France; 7University Hospital, Grenoble, France; 8Pitié Salpêtrière Hospital, APHP, Paris, France; 9University Hospital, Reims, France; 10Necker Hospital, APHP, Paris, France; 11University Hospital, Rouen, France; 12Mondor Hospital, APHP, Paris, France; 13Territorial Hospital, Noumea, France; 14University Hospital, Lille, France; 15University Hospital, Toulouse, France; 16University Hospital, Bordeaux, France; 17University Hospital, Dijon, France; 18University Hospital, Montpellier, France; 19University Hospital, Lyon Sud, France; 20University Hospital, Marseille, France; 21University Hospital, Angers, France; 22University Hospital, Amiens, France.

    Background The place of rituximab in the treatment of acute antibody-mediated rejection (ABMR) is still controversial. The French multicenter double-blind, placebo-controlled RITUX ERAH study included…
  • 2018 American Transplant Congress

    The ATHENA Study: 12 Months Safety and Efficacy Data from Everolimus Combined with Tacrolimus or Cyclosporine Compared to a Standard Tacrolimus-Mycophenolate Regimen in De Novo Kidney Transplant Patients

    B. Suwelack,1 C. Sommerer,1 D. Dragun,1 O. Witzke,1 C. Hugo,1 N. Kamar,2 P. Merville,2 A. Hauser,1 P. Schenker,1 M. Junge,3 B. Nashan,1 F. Thaiss.1

    1Athena Study Group, Germany; 2Athena Study Group, France; 3Novartis, Pharma, Germany.

    The ATHENA study was set up to compare efficacy and safety of everolimus [EVR] combined with tacrolimus [TAC] or cyclosporine A [CyA] vs. a mycophenolic…
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