2018 American Transplant Congress
Pumping Donor Kidneys Reduces DGF and Improves Allograft Survival without Affecting Rejection Rates
Surgery, Duke University, Durham, NC.
Recent evidence suggests that hypothermic machine perfusion of donor kidneys reduces delayed graft function (DGF), but data is sparse on its effect on allograft rejection.…2018 American Transplant Congress
Urinary Microbiome Associated with Chronic Allograft Dysfunction in Kidney Transplants
Background: Microbiome dysbiosis can lead to poor outcomes after kidney transplant (tx) presumably due to immune dysregulation elicited by the microbiome. We hypothesize that chronic…2018 American Transplant Congress
The Combination of Area under Curve of Estimated Glomerular Filtration Rate for 2 Years and Annual Rate Change of Estimated Glomerular Filtration Rate Predicts Long-Term Graft Survival in Kidney Transplants
Improvement of short-term outcomes in kidney transplant (KT) has required clinical trials to evaluate long-term hard outcomes for validation of new therapies. However, because of…2018 American Transplant Congress
Elevated Donor Terminal Creatinine Does Not Appear to Be Associated with Worse Outcomes in Kidney Transplantation
There is justified reluctance to use kidneys from donors with significantly elevated creatinine as they may have severe, irreversible injury. Recently, thanks, in part to…2018 American Transplant Congress
Multi-Drug Resistant Urinary Tract Infections Following Renal Transplant: Risk Factors and Patient Outcomes
Background: Urinary tract infections (UTIs) are the most common infection after kidney transplant (KTx) resulting in significant morbidity and mortality. The reported incidence of UTIs…2018 American Transplant Congress
Reduced Ratio of FoxP3/ RORγt Gene Expression, in Peripheral Blood, is Associated with Acute Allograft Rejection in Recipients with Kidney Transplantation
Introduction:FoxP3 has been well established as an indispensable protein that is required in the development and function of regulatory T cells. On the other hand,…2018 American Transplant Congress
Identifying Patients with CPRA>99.95% Likely to Be Offered Deceased Donor Kidneys
Emory Transplant Center, Atlanta, GA.
The implementation of the new kidney allocation system and priority of kidneys for cPRA=100% subjects revealed a hierarchy difference in allocation to patients with cPRA=99.45%-100%.…2018 American Transplant Congress
Is KDPI Valid for Hepatitis C Aviremic Kidneys?
KDRI is an estimate of post-transplant kidney graft failure. It is based on ten donor factors that independently affect transplant outcomes, including HCV status from…2018 American Transplant Congress
Potential Living Donors Identified through Social Media
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD.
Purpose: We previously described a smartphone application that harnesses social media to increase potential living donors among kidney and liver transplant candidates. We compared potential…2018 American Transplant Congress
Transplanting Kidneys from HCV-Infected Donors into HCV-Negative Recipients: Longer-Term and Extended Results of the THINKER Trial
1University of Pennsylvania, Philadelphia; 2Gift of Life, Philadelphia.
Background: In 2016, 800 kidneys from HCV+ deceased donors were discarded. Short-term (6-month) data from the first 10 subjects in the THINKER-1 trial (NCT02743897; funder:…
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