Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Old World Monkeys Are Not Ideal Transplantation Models for Testing CMAHKO (TKO or GTKO/CMAHKO) Pig Kidneys
T. Yamamoto¹, H. Iwase¹, D. Patel¹, A. Jagdale¹, J. Foote¹, D. Ayares², D. Anderson¹, D. E. Eckhoff¹, D. K. Cooper¹, H. Hara¹
¹University of Alabama at Birmingham, Birmingham, AL, ²Revivicor, Blacksburg, VA
*Purpose: Triple-knockout (TKO) pigs are likely to be an optimal source of organs for transplantation into human recipients, many of whom do not have natural…
2020 American Transplant Congress
Urinary Exosomal Hemopexin, a Validated Diagnostic Marker for Rejection in Kidney Transplant Recipients
J. Lee¹, J. Kim², G. Lee², S. Jeon², H. Noh², J. Lim², H. Jung², J. Choi², J. Cho², S. Park², Y. Kim², C. Kim²
¹Internal Medicine, Daegu Fatima Hospital, Daegu, Korea, Republic of, ²Internal Medicine, Kyungpook National University, Daegu, Korea, Republic of
*Purpose: Urinary exosomal hemopexin was identified as a potential diagnostic candidate for kidney allograft rejection in our previous proteomic study. We validated hemopexin as a…
2020 American Transplant Congress
Prognostic Value of Dd-cfDNA Assay in Acute Renal Rejection Therapy: A Prospective Cohort Study
L. Guo, R. Wang, J. Lv, J. Shen, J. Wu, J. Chen
Kidney Disease Center, First Affiliated Hospital of Zhejiang University, Hangzhou, China
*Purpose: Donor-derived cell free DNA (dd-cfDNA) is a promising biomarker for monitoring allograft status. However, whether it is capable of reflecting real time anti-rejection treatment…
2020 American Transplant Congress
Why Donate to a Stranger? Exploring the Major Motivations of 31 Non-Directed (Altruistic) Living Kidney Donors
A. Maghen¹, G. Mendoza¹, S. E. Connor¹, S. Nassiri¹, L. Kwan¹, E. L. Wood¹, J. Lalezari¹, S. Friedman¹, S. George², S. L. Maliski³, J. L. Veale¹
¹Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA, ²Community Health Sciences, UCLA Fielding School of Public Health, Los Angeles, CA, ³Office of the Dean, University of Kansas Medical Center School of Nursing, Kansas City, KS
*Purpose: With the steady increase in the number of non-directed donors (NDDs) in the U.S. in the past decade, understanding their motivations may help better…
2020 American Transplant Congress
Do Higher Remuzzi Scores Make Good Kidneys Bad? Examining Histologic Criteria within the Framework of Single Kidney Transplantation
V. Fleetwood¹, C. Kensinger², C. Papageorge¹, D. Aufhauser¹, P. Pasha¹, G. Leverson³, B. Welch¹, D. Foley¹
¹Department of Transplantation, University of Wisconsin, Madison, WI, ²Department of Transplantation, Piedmont Transplant Center, Atlanta, GA, ³Department of Statistics, University of Wisconsin, Madison, WI
*Purpose: The Remuzzi score (RS), a histologic tool to assess chronic allograft damage, can guide allocation to single (SKT) or dual (DKT) kidney implantation. RS…
2020 American Transplant Congress
Clazakizumab (Anti-IL-6 Monoclonal) as an Agent to Reduce Donor Specific Hla Antibodies (DSA) and Improve Outcomes in Patients with Chronic & Active Antibody-Mediated Rejection Post-Kidney Transplantation (NCT03380377)
S. C. Jordan, N. Ammerman, M. Toyoda, S. Ge, E. Huang, A. Peng, S. Sethi, R. Najjar, E. Ortiz, M. Chu, A. De Guzman, I. Kim, K. Lim, J. Choi, A. Vo
Cedars Sinai Medical Ctr, Los Angeles, CA
*Purpose: Highly sensitized (HS) patients are at an increased risk for chronic antibody mediated rejection (cABMR) and graft loss due to persistent, deleterious DSA production.…
2020 American Transplant Congress
Multi-National Survey among Nephrologists and Transplant Surgeons About the Suitability and Acceptance of the Marginal Live Kidney Donors Regarding Age Discrepancy
Z. Arabi¹, S. Kaysi², A. Hamad³, M. Bukhari⁴, A. Mateen¹, E. Elhassan¹, A. Altheaby¹
¹KAMC, Riyadh, Saudi Arabia, ²CHR Orleans, Orleans, France, ³The Regional Medical Center, Orangeburg, SC, ⁴Taif University, Taif, Saudi Arabia
*Purpose: Living donor kidney transplantation is the best option for patients on dialysis. There are no guidelines or generally accepted consensus about the acceptable kidney…
2020 American Transplant Congress
Predictors of Kidney Transplant Evaluation Attendance
C. G. Ford¹, Y. Leyva¹, Y. Zhu², E. J. Croswell³, C. Puttarajappa⁴, M. A. Dew³, M. L. Unruh², Y. Ng², L. Myaskovsky¹
¹Center for Healthcare Equity in Kidney Disease, University of New Mexico Health Sciences Center, Albuquerque, NM, ²University of New Mexico School of Medicine, Albuquerque, NM, ³University of Pittsburgh, Pittsburgh, PA, ⁴University of Pittsburgh School of Medicine, Pittsburgh, PA
*Purpose: Given that clinic non-attendance is associated with worse health outcomes for patients and increased burden for providers, we examined whether patient worry about harm…
2020 American Transplant Congress
Cancer Risk in Living Kidney Donors (LKDs) in the United States
E. Engels¹, K. Yu¹, S. Brown¹, K. Pawlish², C. Lynch³, B. Kasiske⁴, J. Snyder⁴, R. Pfeiffer¹
¹National Cancer Institute, Bethesda, MD, ²New Jersey Dept of Health, Trenton, NJ, ³Univ of Iowa, Iowa City, IA, ⁴Scientific Registry of Transplant Recipients, Minneapolis, MN
*Purpose: Individuals who wish to donate a kidney for transplantation are evaluated for transmissible diseases (including cancer) prior to donation. Outcomes in LKDs after donation…
2020 American Transplant Congress
Comparative Analysis of Risk Factors and Outcomes in Kidney Transplant Recipients with Lung Cancer and Those with No Malignancy: UNOS Data Set
H. Patel¹, V. Nissaisorakarn², E. Sula Karrecci¹, N. Agrawal¹, F. Cardarelli¹
¹Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Department of Internal Medicine, Metrowest Medical Center, Boston, MA
*Purpose: Transplant recipients are at increased risk for malignancy. Patients who develop cancer after transplant have worse outcomes, especially those with lung cancer. Transplant-related risk…