Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Targeted Urine Metabolomics for Monitoring Renal Allograft Injury and Immunosuppression
T. Sigdel, A. Schroeder, J. Y. Yang, R. Sarwal, J. Liberto, M. Sarwal
University of California San Francisco, San Francisco, CA
*Purpose: The purpose of this study was to apply high-throughput metabolomics and machine learning to identify surrogate urine metabolite biomarkers for acute rejection vs. BK…
2020 American Transplant Congress
Feasibilty of Hepatitis C NAT Positive Kidney Transplant into Hepatitis C Negative Recipients as Standard of Care
T. Kaur, J. Choi, N. Anwar, M. Anand, S. Shah, S. Bumb, B. Abu Jawdeh, S. Shah, T. Diwan, A. Govil
University of Cincinnati Medical Center, Cincinnati, OH
*Purpose: With advent of direct acting antivirals (DAA) for Hepatitis (Hep) C which have a 96-100% sustained viral remission(SVR), doors have opened for using Hep…
2020 American Transplant Congress
Tertiary Lymphoid Organs in Renal Chronic Allograft Rejection
K. Abou Daya, D. Zhao, K. Biery, M. Oberbarnscheidt
Starzl Transplantation Institute, Pittsburgh, PA
*Purpose: Chronic allograft rejection remains a major obstacle to long-term allograft survival. Tertiary lymphoid organs (TLOs) are ectopic lymphoid structures that arise in non-lymphoid tissues…
2020 American Transplant Congress
Center Effects Substantially Explain Disparities in Access to Kidney Transplants, Yet DSA Effects Remain
D. Stewart, A. Robinson, D. Klassen, A. Wilk
United Network for Organ Sharing, Richmond, VA
*Purpose: The OPTN developed a novel methodology in 2016 to monitor equity in access to deceased donor kidney transplants (Tx) among waitlisted candidates. Results have…
2020 American Transplant Congress
Prolonged In Vivo Perfusion of a Re-Endothelialized Human-Scale Tissue Engineered Kidney Graft
J. S. Uzarski¹, E. E. Russell¹, E. C. Beck¹, M. Holzner², V. Wadhera², D. Adamson², T. Gilbert¹, S. Florman², D. S. Davidow¹, R. Shapiro², J. Ross¹
¹Research & Development, Miromatrix Medical Inc., Eden Prairie, MN, ²Recanati/Miller Institute, Mount Sinai, New York, NY
*Purpose: Advances are desperately needed to increase the supply of transplantable kidneys for the 100,000 patients on the waiting list. Whole organ engineering is one…
2020 American Transplant Congress
Peak DSA Levels Pre-Transplant but Not at Transplant Predict Graft Survival
A. Y. Choi¹, D. Olaso¹, T. Risoli Jr², M. Kuchibhatla², Z. Fitch³, R. Schmitz³, P. M. Schroder³, A. Jackson³, M. Manook³, J. Yoon³, A. B. Farris⁴, J. Kwun³, S. J. Knechtle³
¹Duke University School of Medicine, Durham, NC, ²Duke Biostatistics, Epidemiology, and Research Design Core, Duke University, Durham, NC, ³Department of Surgery, Duke University Medical Center, Durham, NC, ⁴Department of Pathology, Emory University Hospital, Atlanta, GA
*Purpose: Immunization to major histocompatibility complex (MHC) antigens is a barrier in kidney transplantation (KTx) due to higher risk of antibody-mediated rejection (AMR) and graft…
2020 American Transplant Congress
Low-Dose Rabbit Antithymocyte Globulin Induction in Elderly Kidney Transplant Recipients at High Immunologic Risk is Safe and May Prevent Excess Rejection
E. Sartain¹, B. Nettles¹, B. Crowther¹, P. Klem¹, K. Schwarz¹, S. Davis²
¹University of Colorado Hospital, Aurora, CO, ²University of Colorado School of Medicine, Aurora, CO
*Purpose: Patients aged ≥65 years are a growing segment of kidney transplant recipients (KTRs). Consensus on induction immunosuppression in this population is unclear given higher…
2020 American Transplant Congress
Kidney Paired Donation in Brazil
J. Bastos¹, M. Mankowski², S. Gentry³, A. Massie⁴, C. Bisi¹, C. Duarte¹, V. Colares¹, D. Segev⁴, G. Ferreira¹
¹Transplant, Santa Casa de Misericordia de Juiz de Fora, Juiz de Fora, Brazil, ²King Abdullah University of Science and Technology, Thuwal, Saudi Arabia, ³US Naval Academy, Annapolis, MD, ⁴JHU, Baltimore, MD
*Purpose: It is estimated that up to 30% of potential living donor/recipient pairs are unable to proceed to living donor kidney transplantation (LDKT) for immunological…
2020 American Transplant Congress
Would You Rather Receive a High KDPI SCD Kidney or a Lower KDPI ECD Kidney?
V. Gurram, D. Harriman, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, A. Mena-Gutierrez, C. Jay, R. Stratta
Abdominal Transplant Surgery, Wake Forest Baptist Health, Winston Salem, NC
*Purpose: The study purpose was to review our kidney transplant (KT) experience with emphasis placed on outcomes in patients receiving kidneys that were “discordant” within…
2020 American Transplant Congress
Understanding the Decision-Making of 2576 Potential Living Kidney Donors of Different Racial/Ethnic Backgrounds
A. Waterman¹, G. H. Kim¹, Y. Cui², O. N. Ranasinghe¹, J. L. Beaumont², D. Adey³, U. Reddy⁴, B. Campbell⁵, F. L. Weng⁶
¹Division of Nephrology, David Geffen School of Medicine, Los Angeles, CA, ²Terasaki Research Institute, Los Angeles, CA, ³UCSF Health, San Francisco, CA, ⁴UC Irvine, Irvine, CA, ⁵Cedars Sinai Medical Center, Los Angeles, CA, ⁶St. Barnabas Medical Center, Livingston, NJ
*Purpose: To better understand racial/ethnic disparities associated with kidney living donation, this study examined differences in potential living kidney donors’ decision-making, resistance to donation, and…