2020 American Transplant Congress
Kidney Transplant Outcomes in Incarcerated End Stage Renal Disease Patients
Transplant institute, Loma Linda University, San Bernadino, CA
*Purpose: Kidney transplantation remains the treatment of choice for end stage renal disease as it improves mortality and morbidity. Outcomes of incarcerated ESRD patients who…2020 American Transplant Congress
Precision Dosing for Tacrolimus Using Genotypes and Clinical Factors
*Purpose: Variants in CYP3A4/5 genes, clinical factors and drug-drug interactions are associated with tacrolimus (TAC) clearance and dose. This results in high intra- and inter-…2020 American Transplant Congress
Building Kidneys from Stem Cells for Transplantation
*Purpose: Our vision is to build a human kidney by combining human stem cells with porcine kidney extracellular matrix.*Methods: Kidneys were decellularized followed by repopulation…2020 American Transplant Congress
Clinical Outcomes Associated with Long-Term Exposure to Airborne Particulate Pollution in Kidney Transplant Recipients
*Purpose: We aimed to evaluate the relationship of 10-μm particulate matter (PM10) with the risk of graft failure, mortality, and decline of graft function in…2020 American Transplant Congress
Single Cell RNA Sequencing of Normal Kidney Allograft Surveillance Biopsies Show Evidence of Dynamic Glomerular Endothelial Cell Activation
University of Michigan, Ann Arbor, MI
*Purpose: Indication and surveillance biopsy studies show a high prevalence of post kidney transplant (KT) glomerular disease (ElZoghby 2009,Stegall 2017) that cannot be explained by…2020 American Transplant Congress
High Volume, Highly Efficient, Outcome- Centric KPD Program: A Single Center Experience with Direct Exchange Based Strategies
King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia
*Purpose: We report our three and a half year experience with direct exchange (loop) based strategy single center KPD program.*Methods: 1. Inclusion of HLA and…2020 American Transplant Congress
Belatacept-Based, Calcineurin Inhibitor and Corticosteroid Free Immunosuppression: Differential Outcomes Based on Recipient Age
*Purpose: Age-based disparities have been described in calcineurin inhibitor (CNI)-based immunosuppression regimens, but are not well-described for belatacept (BELA)-based regimens. This study analyzed the effect…2020 American Transplant Congress
Mortality Index Should Be Used to Provide Realistic Expectations Regarding Transplant Candidacy
*Purpose: Renal transplant improves outcomes of well-selected elderly patients with end stage renal disease. Older patients with significant comorbidities may not live long enough to…2020 American Transplant Congress
TRANSBIO Study: Clinical Evaluation of Immunobiogram, a Novel In Vitro Diagnostic Immunoassay to Guide Adjustment of Immunosuppressive Therapy in Kidney Transplantation
*Purpose: Immunobiogram (IMBG) is a first-in-class blood-based pharmacodynamic immunoassay that provides the sensitivity/resistance profile of each patient’s lymphocytes to a panel of immunosuppressive drugs (IS).…2020 American Transplant Congress
Clinical Significance of T Cell and B Cell Epitope Prediction as a Risk Factor of De Novo DSA Production after Kidney Transplantation
*Purpose: Chronic antibody-mediated rejection caused by de novo DSA (dnDSA) is a major cause of graft failure. Risk prediction of dnDSA would be important for…
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