ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2020 American Transplant Congress

    Long Term Effect of Tacrolimus Conversion to Sirolimus with Prednisone-Free Regimen in Kidney Allograft Outcomes: A Dynamic Analysis of Graft Survival Using Joint Modeling

    S. H. Park1, B. Ho1, K. Guo1, L. Zhao2, V. Mas3, J. Leventhal4, L. Gallon1

    1Transplant Nephrology, Northwestern University, Chicago, IL, 2Preventive Medicine, Northwestern University, Chicago, IL, 3University of Tennesse, Memphis, TN, 4Transplant Surgery, Northwestern University, Chicago, IL

    *Purpose: Findings on long-term impacts of the mammalian target of rapamycin inhibitor inhibitors on kidney allograft are scarce and mixed. A joint modeling approach can…
  • 2020 American Transplant Congress

    Deficiencies in Family Planning Counseling and Practices in Kidney Transplant Patients

    J. Ritchie1, D. Seidman2, Y. Srisengfa2, E. Perito2, D. Adey2, M. Sarkar2

    1St Luke's University Health Network, Bethlehem, PA, 2UCSF, San Francisco, CA

    *Purpose: Nearly 20% of female kidney transplant(KT) recipients are reproductive-aged. Fertility is often impaired pre-transplant, but rapidly restored after KT. Early and unplanned pregnancies after…
  • 2020 American Transplant Congress

    Recurrence of Igg3Lambda Restricted Cryoglobulinemic Glomerulonephritis in a Renal Allograft: Resolution after Daratumumab Treatment

    S. C. Jordan, R. Vescio, J. Hou, N. Ammerman, R. Najjar, S. Sethi, E. Huang, A. Peng, A. Vo

    Cedars Sinai Medical Ctr, Los Angeles, CA

    *Purpose: C3GN encompasses a group of renal diseases often associated with paraproteinemias. Recurrence in renal allografts is reported. Currently, there are no effective or curative…
  • 2020 American Transplant Congress

    Kidney Transplant Outcomes in Incarcerated End Stage Renal Disease Patients

    R. Rattanavich, T. Hoang, R. Villicana

    Transplant institute, Loma Linda University, San Bernadino, CA

    *Purpose: Kidney transplantation remains the treatment of choice for end stage renal disease as it improves mortality and morbidity. Outcomes of incarcerated ESRD patients who…
  • 2020 American Transplant Congress

    Precision Dosing for Tacrolimus Using Genotypes and Clinical Factors

    M. Al-Kofahi1, W. Oetting1, A. Israni2, D. Schladt3, W. Guan4, B. Wu4, C. Dorr5, R. Remmel6, R. Mannon7, N. Pankratz8, A. Matas9, P. Jacobson1

    1Experimental and Clinical Pharmacology, Univ of MN, College of Pharmacy, Minneapolis, MN, 2Nephrology, Univ of MN and Hennepin HealthCare, Minneapolis, MN, 3Hennepin HealthCare Research Institute, Hennepin HealthCare, Minneapolis, MN, 4Biostatistics, Univ of MN, Minneapolis, MN, 5Nephrology, Hennepin HealthCare, Minneapolis, MN, 6Medicinal Chemistry, Univ of MN, College of Pharmacy, Minneapolis, MN, 7Nephrology, Univ of Alabama, Minneapolis, MN, 8Lab Medicine Pathology, Univ of MN, Minneapolis, MN, 9Surgery, Univ of MN, Minneapolis, MN

    *Purpose: Variants in CYP3A4/5 genes, clinical factors and drug-drug interactions are associated with tacrolimus (TAC) clearance and dose. This results in high intra- and inter-…
  • 2020 American Transplant Congress

    Building Kidneys from Stem Cells for Transplantation

    I. M. Rogers1, J. Whiteley2, T. Chow2, T. Bongolan2, L. Mazilescu3, P. Urbanellis3, S. Ganesh3, M. Selzner3

    1Physiology, University of Toronto, Toronto, ON, Canada, 2LTRI-Sinai Health System, Toronto, ON, Canada, 3MOTU, University Health Network, Toronto, ON, Canada

    *Purpose: Our vision is to build a human kidney by combining human stem cells with porcine kidney extracellular matrix.*Methods: Kidneys were decellularized followed by repopulation…
  • 2020 American Transplant Congress

    Clinical Outcomes Associated with Long-Term Exposure to Airborne Particulate Pollution in Kidney Transplant Recipients

    Y. Kim1, J. Lee2

    1Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, 2Internal Medicine, Seoul National University Boramae Hospital, Seoul, Korea, Republic of

    *Purpose: We aimed to evaluate the relationship of 10-μm particulate matter (PM10) with the risk of graft failure, mortality, and decline of graft function in…
  • 2020 American Transplant Congress

    Single Cell RNA Sequencing of Normal Kidney Allograft Surveillance Biopsies Show Evidence of Dynamic Glomerular Endothelial Cell Activation

    A. S. Naik, R. Menon, E. Otto, C. C. Berthier, E. Farkash, S. P. Norman, M. Kretzler

    University of Michigan, Ann Arbor, MI

    *Purpose: Indication and surveillance biopsy studies show a high prevalence of post kidney transplant (KT) glomerular disease (ElZoghby 2009,Stegall 2017) that cannot be explained by…
  • 2020 American Transplant Congress

    High Volume, Highly Efficient, Outcome- Centric KPD Program: A Single Center Experience with Direct Exchange Based Strategies

    K. Al Meshari, D. Broering, I. Alahmadi, S. Raza, T. Ali, A. Alabbassi, H. Alahdal, F. Alzayer

    King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia

    *Purpose: We report our three and a half year experience with direct exchange (loop) based strategy single center KPD program.*Methods: 1. Inclusion of HLA and…
  • 2020 American Transplant Congress

    Belatacept-Based, Calcineurin Inhibitor and Corticosteroid Free Immunosuppression: Differential Outcomes Based on Recipient Age

    N. Wilson1, A. R. Shields2, D. Kaufman3, A. Wiseman4, A. L. Christianson1, S. Tremblay1, J. P. Leone5, A. J. Matas6, P. West-Thielke7, R. R. Alloway1, E. S. Woodle1

    1U Cincinnati, Cincinnati, OH, 2The Christ Hospital, Cincinnati, OH, 3U Wisconsin, Madison, WI, 4U Colorado, Denver, CO, 5Tampa General, Tampa, FL, 6U Minnesota, Minneapolis, MN, 7U Illinois Chicago, Chicago, IL

    *Purpose: Age-based disparities have been described in calcineurin inhibitor (CNI)-based immunosuppression regimens, but are not well-described for belatacept (BELA)-based regimens. This study analyzed the effect…
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