Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Clinically Adjudicated Deceased Donor AKI and Graft Outcomes
S. G. Mansour¹, N. Khoury¹, S. Vermani¹, R. Koladi¹, I. Hall², P. Reese³, S. Mohan⁴, M. Doshi⁵, M. Harhay⁶, J. Bromberg⁷, M. Thangamani⁸, P. Singh⁹, Y. Jia¹⁰, H. Thiessen-Philbrook¹⁰, E. Akalin¹¹, F. Weng¹², B. Schroeppel¹³, J. Greenberg¹, D. Moledina¹, F. P. Wilson¹, C. Parikh¹⁰
¹Yale, New Haven, CT, ²Utah Univ, Salt Lake City, UT, ³UPenn, Philadelphia, PA, ⁴Columbia, New York, NY, ⁵Univ of Michigan, Ann Arbor, MI, ⁶Drexel, Philadelphia, PA, ⁷Univ of Maryland, College Park, MD, ⁸Cornell, NY, NY, ⁹Thomas Jefferson, Philadelphia, PA, ¹⁰Johns Hopkins, Baltimore, MD, ¹¹Montefiore, Bronx, NY, ¹²St Barnabas, Livingston, NJ, ¹³Univ Hosp, Ulm, Germany
*Purpose: We previously reported that AKI in deceased donors isn't associated with graft failure. As deceased donors undergo significant hemodynamic changes, we hypothesized that reversible…
2020 American Transplant Congress
Comparison of Oropharyngeal Candidiasis Outcomes in Renal Transplant Recipients Receiving Nystatin or No Antifungal Prophylaxis
T. Q. Ky, L. Cotiguala, L. Fitzgerald, K. McMurry, J. Park, S. Tischer
Pharmacy, University of Michigan, Michigan Medicine, Ann Arbor, MI
*Purpose: Oropharyngeal candidiasis (OC) rate in the absence of antifungal prophylaxis has been reported as low as 7.4% after renal transplant. Due to perceived low…
2020 American Transplant Congress
Trends in Transplant Center Responses to the Minimum Acceptance Criteria Across UNOS Regions, 2007-2019
E. M. Roth¹, Q. Yuan², N. Elias²
¹Harvard Medical School, Boston, MA, ²Transplant Center, Massachusetts General Hospital, Boston, MA
*Purpose: The objective of this study was to examine trends in transplant center willingness to accept organs from Public Health Service increased-risk donors for infectious…
2020 American Transplant Congress
American Muslims & Informed Organ Donation Decisions: Findings from a Randomized, Controlled Trial of Religiously-Tailored Education in Mosques
A. I. Padela¹, R. Duivenbode², M. Quinn¹, M. Craig³, M. Saunders¹
¹Department of Medicine, The University of Chicago, Chicago, IL, ²Initiative on Islam and Medicine, The University of Chicago, Chicago, IL, ³The National Kidney Foundation Illinois, Chicago, IL
*Purpose: American Muslims hold more negative attitudes towards organ donation than other American populations, and these attitudes are associated with gaps in biomedical and religious…
2020 American Transplant Congress
TRANSFORM Study (NCT01950819): Application of the Ibox Clinical Trial Simulation Tool to Project Long-Term Kidney Allograft Outcome
G. Divard¹, O. Aubert¹, M. Raynaud¹, J. Pascual², F. Vincenti³, P. Bernhardt⁴, C. Legendre¹, A. Loupy¹, .. on behalf of TRANSFORM Investigators⁵
¹INSERM U970, Paris Transplant Group, Paris, France, ²Department of Nephrology, Hospital del Mar/Universitat Autònoma de Barcelona, Barcelona, Spain, ³Department of Surgery/Kidney Transplant Service, University of California, San Francisco, CA, ⁴Research and Development, Novartis Pharma AG, Basel, Switzerland, ⁵TRANSFORM Investigators, Basel, Switzerland
*Purpose: The development of pharmaceutical agents in transplantation is currently limited by long waits for hard endpoints. We sought to use a risk stratification system…
2020 American Transplant Congress
Gene Expression Signatures Associated with Antibody-Mediated Rejection (ABMR) in Renal Allograft Biopsies (Bx) Are Beneficial to Clarifying ABMR Activity in Ambivalent Cases
H. Zhang¹, C. C. Nast², N. Ammerman³, A. A. Vo³, I. Gallegos³, M. Arevalo³, S. C. Jordan³, M. Toyoda¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, ²Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, ³Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: “Thoroughly validated gene transcripts” in renal Bx was adopted as one of the criteria for ABMR diagnosis in the latest Banff classification. Here, we…
2020 American Transplant Congress
Pre-Renal Transplant Education and Psychosocial Evaluation Positively Impacts Post-Transplant Medication Adherence
M. Jesse¹, D. Kim¹, A. Patel¹, R. Patil¹, S. Bhavsar¹, S. Desai¹, K. Gartrelle¹, A. Eshelman¹, E. Fleagle¹, D. Nicholson¹, E. Clifton²
¹Henry Ford Health System, Detroit, MI, ²University of Michigan, Ann Arbor, MI
*Purpose: An essential element of the organ transplant evaluation process is the preparation of transplant candidates and their social supports. However, approaches to this process…
2020 American Transplant Congress
ATHENA – Patient and Allograft Outcome Differences after Kidney Transplantation – Germany vs. France
F. Thaiss¹, C. Sommerer¹, B. Suwelack¹, D. Dragun¹, I. A. Hauser¹, O. Witzke¹, C. Hugo¹, P. Schenker¹, N. Kamar², P. Merville², I. Kroeger³, M. Junge³, B. Nashan¹
¹Athena, Study Group, Germany, ²Athena, Study Group, France, ³Novartis Pharma GmbH, Nürnberg, Germany
*Purpose: In the ATHENA trial [NCT01843348], efficacy and safety of everolimus in combination with tacrolimus [EVR+TAC] or cyclosporine A [EVR+CyA] vs. TAC and mycophenolic acid…
2020 American Transplant Congress
The Impact of Cold Ischaemia Time on Living Donor Kidney Transplantation Outcomes
S. C. van de Laar¹, M. Robb², R. Hogg², V. Papalois¹, F. J. Dor¹
¹Department of Surgery & Cancer, Imperial College London, Imperial College Renal and Transplant Centre, Hammersmith Hospital, Imperial College Healthcare NHS Trust, White City, London, United Kingdom, ²NHS Blood and Transplant, Bristol, United Kingdom
*Purpose: Living donor KTx (LDKT) provides the best option for patients with end-stage kidney disease (ESKD). ESKD patients who have an incompatible living donor still…
2020 American Transplant Congress
Analysis of 1000 Protocol Kidney Biopsies: Complications, Benefits, and Predictive Potential of Prior Sensitization
M. Eslami¹, J. Patel², S. Karzai¹, D. T. Collins¹, C. Liu¹, J. Jonsson¹, R. Wali¹, J. B. Piper¹
¹Surgery, Inova Fairfax Hospital, Falls Church, VA, ²General Surgery, Pennsylvania State University, State College, PA
*Purpose: Protocol biopsy of kidney transplants can allow for early recognition of treatable findings, both immunologic and non-immunologic. This comes with the risk of biopsy…