Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Lateral Flow Assay to Detect Soluble CD25 after Kidney Transplantation
L. K. Seiler, C. Blume, R. Jonczyk
Faculty of Natural Sciences, Institute of Technical Chemistry, Hannover, Germany
*Purpose: Kidney transplantations are one of the most common transplantations in the world; 80.696 kidneys were transplanted in 2017. Despite tremendous improvements in quality and…
2020 American Transplant Congress
Follow Up of Imlifidase (IdeS) Desensitized Kidney Transplant Recipients
S. C. Jordan¹, R. A. Montgomery², T. Lundgren³, C. Legendre⁴, N. Desai⁵, G. Eckerwall⁶, L. Laxmyr⁶, H. Olsson⁶, A. Runström⁶, Å. Schiött⁶, K. Sjöholm⁶, E. Sonesson⁶, L. Winstedt⁶, T. Lorant⁷, C. Kjellman⁶
¹Cedars Sinai Medical Center, Los Angeles, CA, ²NYU Langone Health Transplant Institute, New York, NY, ³Karolinska University Hospital, Stockholm, Sweden, ⁴Hospital Necker & Paris Descartes University, Paris, France, ⁵Johns Hopkins University, Baltimore, MD, ⁶Hansa Biopharma AB, Lund, Sweden, ⁷Uppsala University, Uppsala, Sweden
*Purpose: 46 highly sensitized patients received kidney transplants after desensitization with imlifidase (currently under investigation) across four Phase 2 clinical trials, and 6-month safety and…
2020 American Transplant Congress
KDPI-Based Kidney Discard Risk Assessment
S. Mehrotra¹, M. Barah², K. Bui³
¹IEMS Department, MEAS, Northwestern University, Evanston, IL, ²IEMS Department, Northwestern University, Evanston, IL, ³Department of Mathematics, University of California, Irvine, Irvine, CA
*Purpose: Despite the vital need, 3,553 (19%) deceased-donor kidneys were discarded in 2018 in the current US allocation system. The discard rate has remained at…
2020 American Transplant Congress
Incidence, Clinical Correlates and Outcomes of Pulmonary Hypertension after Kidney Transplantation: Analysis of Linked U.S. Registry and Medicare Billing Claims
K. Lentine¹, S. Costa², Y. Caliskan³, D. Levine⁴, J. Runo⁵, H. Te⁶, J. Rangaswami⁷, D. Dadhania⁸, D. Axelrod⁹, M. Schnitzler³, H. Xiao¹, B. Kasiske¹⁰, J. Snyder¹⁰, T. Villines¹¹
¹Department of Medicine, Saint Louis Univ, Saint Louis, MO, ²Dartmouth, Lebanon, NH, ³Saint Louis Univ, Saint Louis, MO, ⁴UT Health, San Antonio, TX, ⁵Univ of Wisconsin, Madison, WI, ⁶Univ of Chicago, Chicago, IL, ⁷Einstein Medical Ctr, Philadelphia, PA, ⁸Weill Cornell, New York, NY, ⁹Univ of Iowa, Iowa City, IA, ¹⁰SRTR, Minneapolis, MN, ¹¹Univ of Virginia, Charlottesville, VA
*Purpose: To describe the incidence and mortality implications of pulmonary hypertension (P-HTN) in a large, national cohort of US kidney transplant (KTx) recipients.*Methods: We examined…
2020 American Transplant Congress
Clinical Significance of Late Antibody-Mediated Rejection without Donor Specific Anti-hLA Antibodies
J. Lee¹, E. Kim¹, S. Yang¹, S. Kim¹, B. Lim², H. Choi³, B. Kim⁴, B. Kim⁴, M. Ju⁵, M. Kim¹, S. Kim¹, Y. Kim¹, K. Huh¹
¹Department of Transplantation Surgery, Severance Hospital, Seoul, Korea, Republic of, ²Department of Pathology, Yonsei University College of Medicine, Seoul, Korea, Republic of, ³Department of Internal Medicine, Gangnam Severance Hospital, Seoul, Korea, Republic of, ⁴Department of Internal Medicine, Severance Hospital, Seoul, Korea, Republic of, ⁵Department of Surgery, Gangnam Severance Hospital, Seoul, Korea, Republic of
*Purpose: Late onset antibody-mediated rejection (AMR) is a leading cause of kidney allograft failure. Its diagnosis has been based on a combination of morphologic, immunohistologic…
2020 American Transplant Congress
Comparing Surgical and Urological Complications Over Time in Deceased Donor Kidney Transplantation
A. Mekhaimar, H. Maple, N. Mamode, R. H. Zakri, N. Kessaris
King's College London/Guy's and St Thomas' Hospital, London, United Kingdom
*Purpose: Despite advances in perioperative and post-transplant management over time, complications still occur following deceased donor (DD) kidney transplantation. This study aimed to determine the…
2020 American Transplant Congress
The Centennial Allograft – Can an Organ Function for Over 100 Years in 2 Different Individuals?
A. Gruessner, J. Renz, S. Saggi, R. Gruessner
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: We investigated the occurrence of deceased-donor liver (DDOLT), deceased-donor renal (DDRT), and living-donor renal allografts (LDRT) that have achieved or come close to 100…
2020 American Transplant Congress
The Importance of Caveolin-1 Immunohistochemical Staining for BK Nephropathy Seen after Kidney Transplantation
E. Arpali¹, E. Sunnetcioglu², Y. Özlük², A. Turkmen³, F. S. Oğuz¹
¹Medical Biology, Istanbul University School of Medicine, Istanbul, Turkey, ²Pathology, Istanbul University School of Medicine, Istanbul, Turkey, ³Nephrology, Istanbul University School of Medicine, Istanbul, Turkey
*Purpose: To understand the importance of molecular expression of Caveolin-1 in BKV nephropathy seen after kidney transplantion.*Methods: The kidney transplant patients who had a graft…
2020 American Transplant Congress
Barriers to Organ Transplantation among Underrepresented Racial and Ethnic Groups
M. Parra
Duke Clinical Research Institute, Durham, NC
*Purpose: To understand how known patient, provider, and system-level barriers to organ transplantation differ by race and ethnicity.*Methods: We searched Pubmed and Scopus for articles…
2020 American Transplant Congress
A Novel Formula to Determine Optimal Immunosuppression in Renal Transplant Recipients Treated with Tacrolimus and Mycophenolate Mofetil: Towards Individualized Immunosuppression
O. Pankewycz¹, M. Laftavi¹, E. Onan², D. Rucker¹, D. Wang¹, K. Bhuta¹, R. Gruessner³, A. Gruessner³
¹SUNY, Upstate Medical University, Syracuse, NY, ²Cukurova University, Adana, Turkey, ³SUNY, Downstate Medical University, New York, NY
*Purpose: Tacrolimus (TAC) and mycophenolic acid (MPA) remain the most commonly used drug combination for kidney transplant immunosuppression. Adequate drug dosing is challenging due to…