Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Chronic Active T-Cell Mediated Rejection is Variably Responsive to Immunosuppressive Therapy
V. Kung¹, M. Haas¹, M. Gillespie², E. Huang², R. Sandhu²
¹Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Chronic active T cell-mediated rejection (CACMR) is a newly described variant of kidney allograft rejection associated with long-term graft loss. A key histologic feature…
2020 American Transplant Congress
Use of ICG Fluorescent Imaging in the Assessment of Kidney Transplant Perfusion after a Vascular Complication Requiring Complex Vascular Reconstruction
A. Cracco, D. Reino, S. Joshua, S. Ebaid, J. Vanatta
Cleveland Clinic Florida, Weston, FL
*Purpose: Demonstrate the utility of fluorescent imaging to assess the perfusion of a kidney transplant, after a vascular complication, requiring complex reconstruction.*Methods: Case report.*Results: We…
2020 American Transplant Congress
Donor Derived Parvovirus B19 Infection
W. Peng, J. Lv, J. Wu, J. Chen
Kidney Disease Center, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
*Purpose: At present,donor derived parvovirus B19 infections are rarely reported. Thus, the incidence of donor derived parvovirus B19 infections in solid organ transplant recipients is…
2020 American Transplant Congress
Increasing Access to Kidney Transplantation Through a Satellite Clinic
R. H. Naik, E. Ramos, B. Paueksakon, A. Lyles, L. Smith, J. Lawson, E. Zavala, S. Shawar, J. H. Helderman, S. Karp, D. Shaffer, R. Forbes, B. P. Concepcion
Vanderbilt University Medical Center, Nashville, TN
*Purpose: Distance to a transplant center, a potential barrier for candidates seeking kidney transplant evaluation, can be addressed by satellite clinics. Here we describe our…
2020 American Transplant Congress
Immunohistochemical and Molecular Detection of NK Cells in Kidney Allografts with Antibody Mediated Rejection
E. Farkash, J. Barnes, S. Anand
Pathology, University of Michigan, Ann Arbor, MI
*Purpose: Molecular signatures specific to Natural Killer (NK) cells are closely associated with antibody mediated rejection (AMR) in transplant biopsies. We have developed an immunohistochemical…
2020 American Transplant Congress
Autoimmune Responses to DNA Topoisomerase I Exacerbate Renal Allograft Injury
V. Gorbacheva, R. Fan, S. Miyairi, W. Baldwin, R. Fairchild, A. Valujskikh
Inflammation and Immunity, Cleveland Clinic, Cleveland, OH
*Purpose: Multiple clinical and pre-clinical studies describe correlations between de novo autoimmune responses and poor transplant outcome. We have previously reported that following renal transplantation,…
2020 American Transplant Congress
Does Hope for a Better Future or Fear of Death Motivate Kidney Patients More? A Decisional Balance Exploration of Motivation to Pursue Living Donor Kidney Transplant
H. Rafiqzad¹, A. Wasim¹, A. Rezaeishahreza¹, J. Lam¹, A. Li¹, T. Mahiuddin¹, A. D. Waterman², M. Novak¹, I. Mucsi¹
¹University Health Network, Toronto, ON, Canada, ²University of California, Los Angeles, Los Angeles, CA
*Purpose: We assessed whether the importance attributed to “living a longer life with transplant” versus “fear of death during transplant surgery” by kidney transplant (KT)…
2020 American Transplant Congress
Survival Benefit of Accepting Kidneys from Older Donation after Cardiac Death Donors
S. Yu, J. Long, Y. Yu, M. Bowring, J. Motter, T. Ishaque, D. Segev, J. Garonzik-Wang, A. Massie
Johns Hopkins, Baltimore, MD
*Purpose: Kidneys from older donation after cardiac death (DCD) donors are less likely to be transplanted due to concerns about inferior post-transplant survival. But candidates…
2020 American Transplant Congress
Donor Intervention and Recipient Treatment with Recombinant Human C1 Inhibitor Prevents Delayed Graft Function in a Non-Human Primate Model of Kidney Transplantation
J. A. Reyes¹, C. Blanton¹, M. Eerhart¹, P. Chlebeck¹, M. Springer¹, Y. Ponstein², E. van Amersfoort², J. Torrealba³, Y. Yankol¹, A. D'Allessandro¹, L. Fernandez¹
¹Surgery, University of Wisconsin, Madison, WI, ²Pharming Technologies BV, Leiden, Netherlands, ³Pathology, UT Soutwestern, Dallas, TX
*Purpose: There is currently no FDA-approved treatment to prevent delayed graft function (DGF) in kidney transplantation. We have shown that donor or recipient treatment with…
2020 American Transplant Congress
Survival Benefit of Accepting Kidneys with Acute Kidney Injury
Y. Yu, J. Long, M. Bowring, S. Yu, J. Motter, T. Ishaque, J. Garonzik Wang, A. Massie, D. Segev
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Accepting an acute kidney injury kidney (AKI) or remaining on the waitlist to receive a better offer is under discussed due to the worse…