Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Renal Transplant Outcomes of Kidney-only vs. Multi-organ Deceased Donors
J. Espinales¹, Z. C. Giffen¹, D. Schneider², R. James³, N. Koizumi³, O. Ekwenna¹, J. Ortiz⁴
¹University of Toledo Medical Center, Toledo, OH, ²UC Irvine School of Medicine, Irvine, CA, ³George Mason University, Arlington, VA, ⁴Albany Medical Center, Albany, NY
*Purpose: We sought to determine the relative outcomes of kidneys from kidney-only or multi-organ deceased donors.*Methods: Scientific Registry of Transplant Recipients data from 2010-2019 were…
2021 American Transplant Congress
A Multimodal Interrogation of Human Renal Allografts
D. Dadhania¹, R. Ding¹, H. Xu², C. Lee¹, C. Snopkowski¹, T. Salinas¹, T. Muthukumar¹, J. Lee¹, R. Woodward², M. Grskovic², S. Dholakia², M. Suthanthiran¹
¹Weill Cornell Medicine - NYPH, New York, NY, ²CareDx, New York, NY
*Purpose: Development and validation of noninvasive biomarkers of kidney allograft rejection should improve transplant outcomes. CTOT-04 study validated urinary cell mRNA signature (CTOT04-Sig) for T-cell…
2021 American Transplant Congress
Successful Outcomes from Selected Akin3 Donors Requiring Renal Replacement: Avenue for Increase in Organ Utilization
P. Budhiraja¹, R. L. Heilman¹, M. L. Smith², H. A. Khamash¹, L. Kodali¹, A. A. Moss³, A. K. Mathur³, C. Jadlowiec³, K. S. Reddy³
¹Medicine, Mayo Clinic, Phoenix, AZ, ²Pathology, Mayo Clinic, Phoenix, AZ, ³Surgery, Mayo Clinic, Phoenix, AZ
*Purpose: Our aim was to determine outcomes with transplanting kidneys from deceased donors with severe acute kidney injury requiring acute renal replacement therapy.*Methods: We included…
2021 American Transplant Congress
Right Kidneys and Kidneys with Complex Anatomy are More Likely to be Transplanted to the Waiting List in a National Kidney Paired Donation Program
N. Osbun¹, A. Thomas², A. Waterman³, J. Veale¹, D. Segev², D. Leeser⁴
¹Urology, University of California Los Angeles, Los Angeles, CA, ²Johns Hopkins University, Baltimore, MD, ³University of California Los Angeles, Los Angeles, CA, ⁴East Carolina University, Greenville, NC
*Purpose: In the era of laparoscopic donor nephrectomy, there is a preference for left kidneys with a single renal artery. In paired exchange, the receiving…
2021 American Transplant Congress
Low Immunogenic Donors Improve Kidney Transplant Survival in Sensitized Recipients
D. Bekbolsynov¹, R. Green², B. Mierzejewska¹, M. Rees¹, S. Stepkowski¹
¹University of Toledo, Toledo, OH, ²Bowling Green State University, Bowling Green, OH
*Purpose: Our previous results showed that low immunogenicity (IM) donors improved kidney allograft survival in non-sensitized recipients. Herein, we examined how the level of peak…
2021 American Transplant Congress
Coexistence of BKPyV Lytic Infection and Viral Integration in the Development of BKPyV Diseases After Renal Transplantation
S. Yan¹, Y. Wang¹, Y. Liu¹, W. Deng¹, Z. Yan¹, J. Xu¹, C. Wu², Y. Miao¹
¹Department of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China, ²Departments of Urology & Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
*Purpose: To understand the role of BK Polyomavirus (BKPyV) infection and integration in the pathogenesis of BKPyV-associated diseases.*Methods: Sixteen patients with BKPyV-associated diseases were included,…
2021 American Transplant Congress
Associations of Mammalian Target of Rapamycin Inhibitors with Post-Transplant Malignancies and All-Cause Mortality: Cause-Specific Competing Risks and Composite Outcomes Analyses
A. H. Santos¹, E. Bueno¹, M. A. Leghrouz¹, W. Xuerong²
¹University of Florida, Gainesville, FL, ²University of Rhode Island, Kingston, RI
*Purpose: We investigated the outcomes of malignancies and mortality associated with mammalian target of rapamycin inhibitor (MTORI) regimens in adult kidney transplant (KT) recipients (KTRs).*Methods:…
2021 American Transplant Congress
Interruption of Notch Signaling via Blockade of Delta-Like Ligand 4 Prevents Co-Stimulation Blockade Resistant Allograft Rejection
A. J. Matar, B. P. Lovasik, Y. Dong, D. A. Faber, J. Habib, C. Breeden, J. Regenold, A. Ghosh, A. Stephenson, W. H. Kitchens, A. B. Adams
Emory University Department of Surgery, Atlanta, GA
*Purpose: Co-stimulation blockade (CoB) has emerged as a promising immunosuppression strategy with the advent of Belatacept, a novel CTLA4-Ig fusion protein that blocks CD28-mediated T…
2021 American Transplant Congress
Noninferiority Outcomes Among Undocumented Immigrant Kidney Transplant Recipients in California
H. Ichii¹, N. Eguchi¹, E. Tantisattamo², U. Reddy², A. Ferrey², D. Dafoe¹
¹Surgery, University of California Irvine, Orange, CA, ²Medicine, University of California Irvine, Orange, CA
*Purpose: There are over 2 million undocumented immigrants (UI) in California, where currently, all individuals regardless of immigration status have equal access to kidney transplant(KT).…
2021 American Transplant Congress
A New Triage-based Approach to Managing Transplant Referrals
H. L. Walther
Division of Kidney & Pancreas Transplantation, UCI Health, Orange, CA
*Purpose: To develop and implement a novel triage-based approach to the management of referrals for kidney transplant evaluation*Methods: The transplant nurse coordinator dedicated to referral…