ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "IVIG"

  • 2020 American Transplant Congress

    Posttransplant Prophylactic Therapy with IVIG/Plasmapheresis in Kidney Transplant Recipients with Preformed Donor-Specific Antibodies

    T. V. Sandes-Freitas, B. Neri, J. Junqueira Junior, T. Leite, M. Sales, R. Esmeraldo

    Hospital Geral de Fortaleza, Fortaleza, Brazil

    *Purpose: Patients with high levels of preformed donor-specific antibodies (DSA) are often not considered for kidney transplantation (KT), despite negative CDC-crossmatch, mainly in regions where…
  • 2020 American Transplant Congress

    Osmotic Nephropathy from a Non-Sucrose Based IVIG

    S. Reddy, L. Kodali

    Nephrology, Mayo Clinic, Phoenix, AZ

    *Purpose: We present a case of acute renal failure and hyperkalemia due to osmotic nephropathy from a non-sucrose based IVIG infusion therapy.*Methods: A 67-year-old man…
  • 2019 American Transplant Congress

    Intravenous Immunoglobulin Significantly Reduces Bioavailability of Concomitantly Administered Anti-C5 Monoclonal Antibodies

    S. C. Jordan1, K. Kucher2, M. Bagger2, H. Hockey3, K. Wagner4, N. Ammerman1, J. Choi1, A. Vo1

    1Comprehensive Transplant Center, Cedars-Sinai Medical Ctr, Los Angeles, CA, 2Novartis Institutes for BioMedical Research, Basel, Switzerland, 3Biometrics Matters Ltd, Hamilton, New Zealand, 4Novartis Institutes for BioMedical Research, Cambridge, MA

    *Purpose: Awareness of drug-drug interactions is critical in management of organ transplant recipients. However, there is little understanding of the possibility of biologic agents interfering…
  • 2019 American Transplant Congress

    Predictors of Response to Intravenous Immunoglobulin for Treatment of Polyoma Nephropathy

    S. Sethi, A. Vo, A. Peng, R. Najjar, K. Lim, S. Jordan, E. Huang

    Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: BK nephropathy is an important cause of allograft dysfunction or loss. IVIg is hypothesized to be effective by providing passive immunity to BK virus…
  • 2019 American Transplant Congress

    Reduction of Circulating DSA: Does It Affect Histology?

    M. Gupta1, E. Edusei1, S. Tsai2, M. Magruder2, J. Lee1, J. Lee1, C. Hartono1, T. Muthukumar1, M. Everly3, D. Dadhania1

    1Nephrology, New York Presbyterian Weill Cornell, New York, NY, 2New York Presbyterian Weill Cornell, New York, NY, 3Terasaki Research Institute, Los Angeles, CA

    *Purpose: De novo donor specific antibodies (dnDSA) are reported in 13-30% of kidney transplant recipients. dnDSA has been associated with antibody mediated rejection (AMR) and…
  • 2019 American Transplant Congress

    Desensitization Using Only Polyvalent Immunoglobulins (IVIG) for Kidney Transplantation with Living Donors (LD)

    L. R. Ulisses, J. O. Paixão, P. S. Souza, G. Bezerra, H. Rodrigues, N. Panajatopoulos, F. J. De Paula, E. David-Neto, M. C. R Castro

    Renal Transplant Service, Renal Transplant Service, Hospital das Clinicas and Laboratory of Immunology-LIM-19, Medical School of te University of São Paulo, São Paulo, Brazil, São Paulo, Brazil

    *Purpose: HLA sensitization is a barrier for kidney transplantation. Sensitized patients stay longer on the waiting list and have higher mortality rate and complications while…
  • 2019 American Transplant Congress

    Sequential Dosing of Rituximab and IVIg for Desensitization of Highly-HLA Sensitized (HS) Patients Awaiting HLAi Kidney Transplantation

    A. A. Vo, E. Huang, S. Williamsons, C. Myers, A. Peng, R. Najjar, S. Sethi, K. Lim, N. Ammerman, S. C. Jordan

    Kidney Transplant, Cedars Sinai Medical Ctr, Los Angeles, CA

    *Purpose: Recent observations suggest that the use of IVIg + rituximab has a critical role in modifying allo-reactive B-cells prior to HLAi kidney transplantation, thus…
  • 2019 American Transplant Congress

    Pre-emptive Ivig For Dsa Positive Living Donor Kidney Transplant Recipients

    B. Abdalla1, D. Kellner2, A. Diaz2, Y. Zheng3, E. Reed4, Q. J. Zhang4

    1Medicine, Division of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA, 2David Geffen School of Medicine at UCLA, Los Angeles, CA, 3UCLA Immunogenetics Center, Los Angeles, CA, 4Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA

    *Purpose: Intravenous immunoglobulin (IVIG) is used in desensitization regimens to modulate anti-human leukocyte antigen (HLA) donor-specific antibody (DSA) to facilitate transplantation of sensitized patients, however,…
  • 2019 American Transplant Congress

    Effects of IVIG Therapy and FcγR Polymorphisms on BK Virus Nephropathy in Kidney Transplant Recipients

    D. I. Min1, Y. Chang2, T. Shah3

    1Western Univ of Health Sciences, Los Angeles, CA, 2Mendez National Institute of Transplantation Foundation, Los Angeles, CA, 3St. Vincent Medical Center, Los Angeles, CA

    *Purpose: BK Virus Nephropathy (BKVN) is a major complication in kidney transplant patients. Although standard treatment for BKVN is immunosuppression reduction and/or using leflunomide, studies…
  • 2018 American Transplant Congress

    Modified Protocol for ABO-Incompatible Living Donor Liver Transplantation with Rituximab and Intravenous Immunoglobulin without Plasma Exchange

    B-.G. Na, E. Lee, S. Kim, S. Park.

    Center for Liver Cancer, National Cancer Center, Il-san Donggu, Goyang, Republic of Korea.

    Purpose: Since a variety of desensitization strategies including rituximab, intravenous immunoglobulin (IVIG), and plasma exchange (PE) have been introduced, the survival and outcomes of recipients…
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